{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T03:04:08Z","timestamp":1790132648315,"version":"4.0.1"},"reference-count":63,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2021,1,26]],"date-time":"2021-01-26T00:00:00Z","timestamp":1611619200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100012774","name":"Innovationsfonden","doi-asserted-by":"publisher","award":["5164\u201000001B9"],"award-info":[{"award-number":["5164\u201000001B9"]}],"id":[{"id":"10.13039\/100012774","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003554","name":"Lundbeckfonden","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003554","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Psychiatr Scand"],"published-print":{"date-parts":[[2021,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>The MONARCA I and II trials were negative but suggested that smartphone\u2010based monitoring may increase quality of life and reduce perceived stress in bipolar disorder (BD). The present trial was the first to investigate the effect of smartphone\u2010based monitoring on the rate and duration of readmissions in BD.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This was a randomized controlled single\u2010blind parallel\u2010group trial. Patients with BD (ICD\u201010) discharged from hospitalization in the Mental Health Services, Capital Region of Denmark were randomized 1:1 to daily smartphone\u2010based monitoring including a feedback loop (+ standard treatment) or to standard treatment for 6 months. Primary outcomes: the rate and duration of psychiatric readmissions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      We included 98 patients with BD. In ITT analyses, there was no statistically significant difference in rates (hazard rate: 1.05, 95% CI: 0.54; 1.91,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.88) or duration of readmission between the two groups (B: 3.67, 95% CI: \u22124.77; 12.11,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.39). There was no difference in scores on the Hamilton Depression Rating Scale (B\u00a0=\u00a0\u22120.11, 95% CI: \u22122.50; 2.29,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.93). The intervention group had higher scores on the Young Mania Rating Scale (B: 1.89, 95% CI: 0.0078; 3.78,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.050). The intervention group reported lower levels of perceived stress (B: \u20107.18, 95% CI: \u221213.50; \u22120.86,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.026) and lower levels of rumination (B: \u22126.09, 95% CI: \u221211.19; \u22121.00,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0=\u00a00.019).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Smartphone\u2010based monitoring did not reduce rate and duration of readmissions. There was no difference in levels of depressive symptoms. The intervention group had higher levels of manic symptoms, but lower perceived stress and rumination compared with the control group.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/acps.13274","type":"journal-article","created":{"date-parts":[[2020,12,24]],"date-time":"2020-12-24T07:26:43Z","timestamp":1608794803000},"page":"453-465","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":45,"title":["Reducing the rate of psychiatric re\u2010admissions in bipolar disorder using smartphones\u2014The RADMIS trial"],"prefix":"10.1111","volume":"143","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0462-6444","authenticated-orcid":false,"given":"Maria","family":"Faurholt\u2010Jepsen","sequence":"first","affiliation":[{"name":"Copenhagen Affective Disorder Research Center (CADIC) Psychiatric Center Copenhagen Rigshospitalet Copenhagen 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