{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T22:05:02Z","timestamp":1790287502099,"version":"4.1.0"},"reference-count":63,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2021,3,17]],"date-time":"2021-03-17T00:00:00Z","timestamp":1615939200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Psychiatr Scand"],"published-print":{"date-parts":[[2021,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Information on societal cost of patients with schizotypal disorder is limited. The aim was to investigate the societal costs of schizotypal disorder before and after initial diagnosis including both patients and their spouses.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A register\u2010based cohort study of 762 patients with incident schizotypal disorder (ICD\u201010; F21) including their spouses and 3048 matched controls, during 2002 to 2016. Total healthcare costs, home care costs, and costs of lost productivity of patients and spouses were included in the analysis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Total costs amounted \u20ac47,215 per year for patients with schizotypal disorder, which was fifteen times higher than the matched controls. Of these, 41% were healthcare and home care costs and 59% were costs of lost productivity. Healthcare costs and costs of lost productivity were increased during five years before initial diagnosis of schizotypal disorder. Total costs of spouses to patients were \u20ac21,384 compared with \u20ac 2519 among spouses of controls. 75% of the total costs of spouses to patients were related to lost productivity. The total costs were higher than the costs of borderline personality disorder, but on the same level as the costs of schizophrenia identified in earlier comparable studies.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The total societal costs of patients with schizotypal disorder drawn from national registers differed substantially from the controls representing the general population. As evidence\u2010based recommendations for diagnoses and treatment of patients with schizotypal disorder do not exist, future research should focus on developing effective treatment for this group of patients to reduce cost of illness.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/acps.13292","type":"journal-article","created":{"date-parts":[[2021,3,2]],"date-time":"2021-03-02T02:36:52Z","timestamp":1614652612000},"page":"60-71","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Costs of schizotypal disorder: A matched\u2010controlled nationwide register\u2010based study of patients and spouses"],"prefix":"10.1111","volume":"144","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6194-1336","authenticated-orcid":false,"given":"Lene Halling","family":"Hastrup","sequence":"first","affiliation":[{"name":"Psychiatric Research Unit Psychiatry Region Zealand Slagelse Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6986-5254","authenticated-orcid":false,"given":"Poul","family":"Jennum","sequence":"additional","affiliation":[{"name":"Faculty of Health Sciences Danish Center for Sleep Medicine Neurophysiology Clinic University of Copenhagen Rigshospitalet Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rikke","family":"Ibsen","sequence":"additional","affiliation":[{"name":"i2minds Aarhus Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jakob","family":"Kjellberg","sequence":"additional","affiliation":[{"name":"VIVE \u2013 The Danish Center for Social Science Research Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erik","family":"Simonsen","sequence":"additional","affiliation":[{"name":"Psychiatric Research Unit Psychiatry Region Zealand Slagelse Denmark"},{"name":"Department of Clinical Medicine University of Copenhagen Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,3,17]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.187.48.s49"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.1979.01780010023001"},{"key":"e_1_2_9_4_1","doi-asserted-by":"crossref","unstructured":"World Health Organisation.The ICD\u201010 classification of mental and behavioral disorders. Clinical descriptions an diagnostic guidelines1993.https:\/\/doi.org\/10.1177\/1071100715600286","DOI":"10.1177\/1071100715600286"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.books.9780890425596"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.58.6.590"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.comppsych.2005.06.002"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1521\/pedi.1991.5.2.178"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.162.10.1911"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41537-018-0062-8"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1080\/15622970701685224"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1177\/1534650111427076"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11920-014-0452-1"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.159.2.276"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1017\/S003329170400354X"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.schres.2012.12.012"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0447.1991.tb01423.x"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.psychres.2013.06.019"},{"key":"e_1_2_9_19_1","unstructured":"RazzoukD.Mental health economics: The costs and benefits of psychiatric care;2017.https:\/\/doi.org\/10.1007\/978\u20103\u2010319\u201055266\u20108"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/acps.13094"},{"key":"e_1_2_9_21_1","first-page":"242","article-title":"Societal cost\u2010of\u2010illness of borderline personality disorder","volume":"42","author":"Wagner T","year":"2013","journal-title":"Krankheitskosten der Borderline Pers. aus Ges. Perspekt."},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.4088\/JCP.v65n0105"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.158.2.295"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1017\/ipm.2018.30"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291708004911"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1521\/pedi.2012.26.4.593"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.euroneuro.2011.08.008"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-1331.2011.03590.x"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.4088\/JCP.v69n0212"},{"key":"e_1_2_9_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eurpsy.2007.04.001"},{"key":"e_1_2_9_31_1","article-title":"The societal cost of schizophrenia in Sweden","author":"Ekman M","year":"2013","journal-title":"J Ment Health Policy Econ"},{"key":"e_1_2_9_32_1","doi-asserted-by":"publisher","DOI":"10.1093\/schbul\/sbv141"},{"key":"e_1_2_9_33_1","doi-asserted-by":"publisher","DOI":"10.1093\/schbul\/sbz041"},{"key":"e_1_2_9_34_1","doi-asserted-by":"publisher","DOI":"10.1097\/HRP.0b013e3182a75c2c"},{"key":"e_1_2_9_35_1","doi-asserted-by":"publisher","DOI":"10.1177\/1403494811401482"},{"key":"e_1_2_9_36_1","doi-asserted-by":"publisher","DOI":"10.1177\/1403494810387965"},{"key":"e_1_2_9_37_1","doi-asserted-by":"publisher","DOI":"10.1177\/1403494810394718"},{"key":"e_1_2_9_38_1","doi-asserted-by":"publisher","DOI":"10.1177\/1403494810394717"},{"key":"e_1_2_9_39_1","doi-asserted-by":"publisher","DOI":"10.1177\/1403494811405098"},{"key":"e_1_2_9_40_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-319-55266-8_29"},{"key":"e_1_2_9_41_1","first-page":"239","volume-title":"Estimation of Costs for Community Mental Health Services","author":"Becker P","year":"2017"},{"key":"e_1_2_9_42_1","unstructured":"GlickHA DoshiJA SonnadSS PolskyD.Economic Evaluation in Clinical Trials;2007."},{"key":"e_1_2_9_43_1","first-page":"1","article-title":"Low vocational outcome among people diagnosed with borderline personality disorder during first admission to mental health services in Denmark: a nationwide 9\u2010year register\u2010based study","volume":"5","author":"Hastrup LH","year":"2018","journal-title":"J Pers Disord"},{"key":"e_1_2_9_44_1","doi-asserted-by":"publisher","DOI":"10.2165\/00019053-200826020-00005"},{"key":"e_1_2_9_45_1","doi-asserted-by":"publisher","DOI":"10.1521\/pedi.2012.26.6.956"},{"key":"e_1_2_9_46_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamapsychiatry.2015.3192"},{"key":"e_1_2_9_47_1","doi-asserted-by":"publisher","DOI":"10.4088\/JCP.v69n0212"},{"key":"e_1_2_9_48_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbr.2010.11.042"},{"key":"e_1_2_9_49_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.schres.2007.11.005"},{"key":"e_1_2_9_50_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-3223(02)01426-9"},{"key":"e_1_2_9_51_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005053-200111000-00004"},{"key":"e_1_2_9_52_1","doi-asserted-by":"publisher","DOI":"10.1016\/0165-1781(95)02709-2"},{"key":"e_1_2_9_53_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.schres.2008.11.020"},{"key":"e_1_2_9_54_1","doi-asserted-by":"publisher","DOI":"10.1037\/0021-843X.110.2.290"},{"key":"e_1_2_9_55_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1167.2010.02946.x"},{"key":"e_1_2_9_56_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.euroneuro.2011.05.001"},{"key":"e_1_2_9_57_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10198-010-0280-0"},{"key":"e_1_2_9_58_1","article-title":"Borderline personality and criminality","author":"Sansone RA","year":"2009","journal-title":"Psychiatry (Edgmont)"},{"key":"e_1_2_9_59_1","doi-asserted-by":"publisher","DOI":"10.1503\/cmaj.090618"},{"key":"e_1_2_9_60_1","doi-asserted-by":"publisher","DOI":"10.1053\/comp.2001.19749"},{"key":"e_1_2_9_61_1","doi-asserted-by":"publisher","DOI":"10.1111\/acps.12261"},{"key":"e_1_2_9_62_1","doi-asserted-by":"publisher","DOI":"10.1159\/000478989"},{"key":"e_1_2_9_63_1","doi-asserted-by":"publisher","DOI":"10.1093\/schbul\/sby053"},{"key":"e_1_2_9_64_1","doi-asserted-by":"publisher","DOI":"10.1093\/schbul\/sbp027"}],"container-title":["Acta Psychiatrica Scandinavica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/acps.13292","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/acps.13292","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/acps.13292","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,30]],"date-time":"2023-08-30T05:42:15Z","timestamp":1693374135000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/acps.13292"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,3,17]]},"references-count":63,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021,7]]}},"alternative-id":["10.1111\/acps.13292"],"URL":"https:\/\/doi.org\/10.1111\/acps.13292","archive":["Portico"],"relation":{"has-review":[{"id-type":"doi","id":"10.1111\/ACPS.13292\/v1\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/ACPS.13292\/v1\/review2","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/ACPS.13292\/v3\/response1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/ACPS.13292\/v1\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/ACPS.13292\/v2\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/ACPS.13292\/v2\/review2","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/ACPS.13292\/v2\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/ACPS.13292\/v2\/response1","asserted-by":"object"},{"id-type":"doi","id":"10.1111\/ACPS.13292\/v3\/decision1","asserted-by":"object"}]},"ISSN":["0001-690X","1600-0447"],"issn-type":[{"value":"0001-690X","type":"print"},{"value":"1600-0447","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,3,17]]},"assertion":[{"value":"2020-11-05","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-02-25","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-03-17","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}