{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T02:39:32Z","timestamp":1772159972382,"version":"3.50.1"},"reference-count":35,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2021,4,13]],"date-time":"2021-04-13T00:00:00Z","timestamp":1618272000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Psychiatr Scand"],"published-print":{"date-parts":[[2021,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To determine how mental disorders and psychopharmacological treatments before and during COVID\u201019 hospital admissions are related to mortality.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Subjects included in the study were all adult patients with a diagnosis of COVID\u201019, confirmed clinically and by PCR, who were admitted to a tertiary university hospital in Badalona (Spain) between March 1 and November 17, 2020. Data were extracted anonymously from computerized clinical records.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      2,150 subjects were included, 57% males, mean age 61\u00a0years. History of mental disorders was registered in 957 (45%). Throughout admission,\n                      <jats:italic>de novo<\/jats:italic>\n                      diagnosis of mood or anxiety, stress, or adjustment disorder was made in 12% of patients without previous history. Delirium was diagnosed in 10% of cases. 1011 patients (47%) received a psychotropic prescription during admission (36% benzodiazepines, 22% antidepressants, and 21% antipsychotics). Mortality rate was 17%. Delirium during admission and history of mood disorder were independently associated with higher mortality risk (hazard ratios, 1.39 and 1.52 respectively), while previous year's treatments with anxiolytics\/hypnotics and antidepressants were independently associated with lower mortality risk (hazard ratios, 0.47 and 0.43, respectively).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Mental symptoms are very common in patients hospitalized for COVID\u201019 infection. Detecting, diagnosing, and treating them is key to determining the prognosis of the disease and functional recovery.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/acps.13304","type":"journal-article","created":{"date-parts":[[2021,4,1]],"date-time":"2021-04-01T06:36:45Z","timestamp":1617259005000},"page":"526-534","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":45,"title":["Mental disorders, psychopharmacological treatments, and mortality in 2150 COVID\u201019 Spanish inpatients"],"prefix":"10.1111","volume":"143","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0705-295X","authenticated-orcid":false,"given":"Crisanto","family":"Diez\u2010Quevedo","sequence":"first","affiliation":[{"name":"Psychiatry Service Hospital Universitari Germans Trias i Pujol IGTP Campus Can Ruti Badalona Spain"},{"name":"Department of Psychiatry and Legal Medicine Universitat Aut\u00f2noma de Barcelona Bellaterra 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