{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T13:37:01Z","timestamp":1780580221079,"version":"3.54.1"},"reference-count":50,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2021,9,24]],"date-time":"2021-09-24T00:00:00Z","timestamp":1632441600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100009228","name":"Region \u00d6rebro l\u00e4n","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100009228","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Psychiatr Scand"],"published-print":{"date-parts":[[2021,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>The primary aim was to determine whether electroconvulsive therapy (ECT) is associated with reduced risk of psychiatric readmission in major depressive disorder (MDD).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This study was based on data from multiple Swedish population\u2010based registries. All adult patients admitted to any Swedish hospital for moderate\u2010to\u2010severe MDD between 2012 and 2018 were included. Participants were divided into two groups depending on whether they received ECT during inpatient care. Follow\u2010up was set at 30 and 90\u00a0days from discharge. Data were analyzed using logistic regression, and matching was conducted.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 27,851 unique patients contributed to 41,916 admissions. ECT was used in 26.8% of admissions. In the main multivariate analysis, the risk of both 30\u2010 and 90\u2010day readmission was lower in the ECT group than in the non\u2010ECT group. In a matched sensitivity model, the results pointed in the same direction for readmission risk within 30\u00a0days, but statistical significance was not reached. ECT\u2010treated subgroups with superior outcomes on readmission risk compared with non\u2010ECT treatment were older, unemployed, married, or widowed patients, those treated with antipsychotics or benzodiazepines before admission, with psychotic features, prior psychiatric hospitalizations, or family history of suicide. However, in patients below 35\u00a0years of age, ECT was associated with increased readmission risk.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This study suggests that ECT reduces the risk of psychiatric readmission in certain subgroups of patients with MDD. Since patients receiving ECT tend to be more difficult to treat, there is a risk of residual confounding.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/acps.13373","type":"journal-article","created":{"date-parts":[[2021,9,15]],"date-time":"2021-09-15T03:53:14Z","timestamp":1631677994000},"page":"599-625","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Electroconvulsive therapy and psychiatric readmission in major depressive disorder \u2013 A population\u2010based register study"],"prefix":"10.1111","volume":"144","author":[{"given":"Linnea","family":"Stenmark","sequence":"first","affiliation":[{"name":"Faculty of Medicine and Health \u00d6rebro University \u00d6rebro Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9663-3571","authenticated-orcid":false,"given":"Charles H.","family":"Kellner","sequence":"additional","affiliation":[{"name":"Department of Psychiatry and Behavioral Sciences Medical University of South Carolina Charleston SC USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mikael","family":"Land\u00e9n","sequence":"additional","affiliation":[{"name":"Department of Medical Epidemiology and Biostatistics Karolinska Institutet Stockholm Sweden"},{"name":"Institute of Neuroscience and Physiology The Sahlgrenska Academy at Gothenburg University Gothenburg Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Irya","family":"Larsson","sequence":"additional","affiliation":[{"name":"Faculty of Medicine and Health \u00d6rebro University \u00d6rebro Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mussie","family":"Msghina","sequence":"additional","affiliation":[{"name":"Faculty of Medicine and Health \u00d6rebro University \u00d6rebro Sweden"},{"name":"Department of Clinical Neuroscience Karolinska Institutet Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7454-3065","authenticated-orcid":false,"given":"Axel","family":"Nordenskj\u00f6ld","sequence":"additional","affiliation":[{"name":"Faculty of Medicine and Health \u00d6rebro University \u00d6rebro Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,9,24]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291712001511"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(18)32279-7"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2013.03.003"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.4088\/JCP.14m09298"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cpr.2018.07.005"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.psychres.2009.12.003"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/ijnp\/pyv076"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2215-0366(17)30134-7"},{"issue":"5","key":"e_1_2_9_10_1","first-page":"355","article-title":"Effectiveness and outcome predictors of long\u2010term lithium prophylaxis in unipolar major depressive disorder","volume":"28","author":"Baethge C","year":"2003","journal-title":"J Psychiatry Neurosci"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1192\/bjo.2019.37"},{"key":"e_1_2_9_12_1","volume-title":"Practice Guideline for the Treatment of Patients with Major Depressive Disorder","author":"American Psychiatric Association","year":"2010"},{"key":"e_1_2_9_13_1","volume-title":"Clinical Practice Guideline for the Treatment of Depression Across Three Age Cohorts","author":"American Psychiatric Association","year":"2019"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamapsychiatry.2017.1378"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/YCT.0000000000000628"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpsychires.2019.11.016"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.1994.tb06512.x"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(03)12705-5"},{"key":"#cr-split#-e_1_2_9_19_1.1","unstructured":"Socialstyrelsen.Bortfall och kvalitet om Patientregistret [Internet]. 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