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However, conclusions have been limited by inconsistent findings across different maltreatment subtypes and social domains. We conducted a systematic review and meta\u2010analysis to quantify associations between childhood maltreatment (overall and subtypes \u2010 physical, emotional and\/or sexual abuse, and\/or physical and\/or emotional neglect) and different domains of social functioning and social cognition in adults with affective disorders (bipolar disorder or major depressive disorder). We also examined effect moderators and mediators of these associations.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      A systematic search was performed on 12.12.2022 which identified 29 studies included in qualitative synthesis (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u20093022 individuals with affective disorders), of which 27 (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u20092957) were pooled in meta\u2010analyses. Across studies, five social functioning and five social cognition domains were examined, of which four domains of social functioning and two domains of social cognition had sufficient data for meta\u2010analysis (PROSPERO CRD42022288976).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Social functioning: childhood maltreatment was associated with lower global social functioning (\n                      <jats:italic>r<\/jats:italic>\n                      \u2009=\u2009\u22120.11 to \u22120.20), poorer interpersonal relations (\n                      <jats:italic>r<\/jats:italic>\n                      \u2009=\u2009\u22120.18 to \u22120.33), and with aggressive behaviour (\n                      <jats:italic>r<\/jats:italic>\n                      \u2009=\u20090.20\u20130.29) but was unrelated to vocational functioning. Emotional abuse and emotional neglect showed the largest magnitudes of effect. Social cognition: there was no meta\u2010analytic evidence of associations between maltreatment and social cognition domains. Exploratory moderation analyses did not identify any consistent moderators. Narrative synthesis identified attachment style as possible moderator, and sensory patterns, anxiety, and depressive symptoms as possible mediators between childhood maltreatment and social outcomes. Overall, the available evidence was limited, particularly in relation to social cognition.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Adults with affective disorders are at risk of social functioning difficulties after childhood maltreatment exposure, an effect observed across multiple maltreatment subtypes, social functioning domains, and diagnoses. Addressing social functioning problems may benefit maltreated adults with both bipolar disorder and major depressive disorder.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/acps.13557","type":"journal-article","created":{"date-parts":[[2023,4,27]],"date-time":"2023-04-27T20:09:42Z","timestamp":1682626182000},"page":"142-164","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":71,"title":["Association between childhood maltreatment and social functioning in individuals with affective disorders: A systematic review and\n                    <scp>meta\u2010analysis<\/scp>"],"prefix":"10.1111","volume":"148","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8589-7384","authenticated-orcid":false,"given":"Natalia E.","family":"Fares\u2010Otero","sequence":"first","affiliation":[{"name":"Bipolar and Depressive Disorders Unit, Department of Psychiatry and Psychology, Hospital Cl\u00ednic, Institute of Neurosciences (ICN) Department of Medicine, Faculty of Medicine and Health Sciences, Universitat de Barcelona (UB)  Barcelona Catalonia Spain"},{"name":"Institut d'Investigacions Biom\u00e8diques August Pi i Sunyer (IDIBAPS), Network Centre for Biomedical Research in Mental Health (CIBERSAM) Health Institute Carlos III (ISCIII)  Barcelona Catalonia Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michele","family":"De Prisco","sequence":"additional","affiliation":[{"name":"Bipolar and Depressive Disorders Unit, Department of Psychiatry and Psychology, Hospital Cl\u00ednic, Institute of Neurosciences (ICN) Department of Medicine, Faculty of Medicine and Health Sciences, Universitat de Barcelona (UB)  Barcelona Catalonia Spain"},{"name":"Institut d'Investigacions Biom\u00e8diques August Pi i Sunyer (IDIBAPS), Network Centre for Biomedical Research in Mental Health (CIBERSAM) Health Institute Carlos III (ISCIII)  Barcelona Catalonia 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Psychology, Hospital Cl\u00ednic, Institute of Neurosciences (ICN) Department of Medicine, Faculty of Medicine and Health Sciences, Universitat de Barcelona (UB)  Barcelona Catalonia Spain"},{"name":"Institut d'Investigacions Biom\u00e8diques August Pi i Sunyer (IDIBAPS), Network Centre for Biomedical Research in Mental Health (CIBERSAM) Health Institute Carlos III (ISCIII)  Barcelona Catalonia Spain"},{"name":"Department of Clinical Neuroscience, Centre for Psychiatric Research and Education Karolinska Institutet  Stockholm Sweden"},{"name":"Department of Psychosis Studies Institute of Psychiatry, Psychology and Neuroscience, King's College London  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3436-3358","authenticated-orcid":false,"given":"Sarah L.","family":"Halligan","sequence":"additional","affiliation":[{"name":"Department of Psychology University of Bath  Bath UK"},{"name":"Department of Psychiatry and Mental Health University of Cape Town  Cape Town South Africa"},{"name":"Department of Psychiatry Stellenbosch University  Stellenbosch South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0548-0053","authenticated-orcid":false,"given":"Eduard","family":"Vieta","sequence":"additional","affiliation":[{"name":"Bipolar and Depressive Disorders Unit, Department of Psychiatry and Psychology, Hospital Cl\u00ednic, Institute of Neurosciences (ICN) Department of Medicine, Faculty of Medicine and Health Sciences, Universitat de Barcelona (UB)  Barcelona Catalonia Spain"},{"name":"Institut d'Investigacions Biom\u00e8diques August Pi i Sunyer (IDIBAPS), Network Centre for Biomedical Research in Mental Health (CIBERSAM) Health Institute Carlos III (ISCIII)  Barcelona Catalonia Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anabel","family":"Martinez\u2010Aran","sequence":"additional","affiliation":[{"name":"Bipolar and Depressive 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