{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T02:04:48Z","timestamp":1790820288786,"version":"4.1.0"},"reference-count":56,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2023,6,7]],"date-time":"2023-06-07T00:00:00Z","timestamp":1686096000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Psychiatr Scand"],"published-print":{"date-parts":[[2024,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To assess the postpartum depression (PPD) risk in women with postpartum hemorrhage (PPH) and moderators.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We identified observational studies of PPD rates in women with versus without PPH in Embase\/Medline\/PsychInfo\/Cinhail in 09\/2022. Study quality was evaluated using the Newcastle\u2010Ottawa\u2010Scale. Our primary outcome was the odds ratio (OR, 95% confidence intervals [95%CI]) of PPD in women with versus without PPH. Meta\u2010regression analyses included the effects of age, body mass index, marital status, education, history of depression\/anxiety, preeclampsia, antenatal anemia and C\u2010section; subgroup analyses were based on PPH and PPD assessment methods, samples with versus without history of depression\/anxiety, from low\u2010\/middle\u2010 versus high\u2010income countries. We performed sensitivity analyses after excluding poor\u2010quality studies, cross\u2010sectional studies and sequentially each study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      One, five and three studies were rated as good\u2010, fair\u2010 and poor\u2010quality respectively. In nine studies (k\u2009=\u200910 cohorts, n\u2009=\u2009934,432), women with PPH were at increased PPD risk compared to women without PPH (OR\u2009=\u20091.28, 95% CI\u2009=\u20091.13 to 1.44,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001), with substantial heterogeneity (\n                      <jats:italic>I<\/jats:italic>\n                      <jats:sup>2<\/jats:sup>\n                      \u2009=\u200998.9%). Higher PPH\u2010related PPD ORs were estimated in samples with versus without history of depression\/anxiety or antidepressant exposure (OR\u2009=\u20091.37, 95%CI\u2009=\u20091.18 to 1.60, k\u2009=\u20096, n\u2009=\u200955,212, versus 1.06, 95%CI\u2009=\u20091.04 to 1.09, k\u2009=\u20093, n\u2009=\u2009879,220,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001) and in cohorts from low\u2010\/middle\u2010 versus high\u2010income countries (OR\u2009=\u20091.49, 95%CI\u2009=\u20091.37 to 1.61, k\u2009=\u20094, n\u2009=\u20099197, versus 1.13, 95%CI\u2009=\u20091.04 to 1.23, k\u2009=\u20096, n\u2009=\u2009925,235,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). After excluding low\u2010quality studies the PPD OR dropped (1.14, 95%CI\u2009=\u20091.02 to 1.29, k\u2009=\u20096, n\u2009=\u2009929,671,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.02).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Women with PPH had increased PPD risk amplified by history of depression\/anxiety, whereas more data from low\u2010\/middle\u2010income countries are required.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/acps.13583","type":"journal-article","created":{"date-parts":[[2023,6,8]],"date-time":"2023-06-08T00:34:24Z","timestamp":1686184464000},"page":"274-283","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":27,"title":["Postpartum hemorrhage and postpartum depression: A systematic review and meta\u2010analysis of observational studies"],"prefix":"10.1111","volume":"150","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3851-4117","authenticated-orcid":false,"given":"Georgios","family":"Schoretsanitis","sequence":"first","affiliation":[{"name":"Department of Psychiatry, Psychotherapy and Psychosomatics, Hospital of Psychiatry University of Zurich  Zurich Switzerland"},{"name":"Department of Psychiatry The Zucker Hillside Hospital, Northwell Health  Glen Oaks New York USA"},{"name":"Department of Psychiatry Zucker School of Medicine at Northwell\/Hofstra  Hempstead New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chiara","family":"Gastaldon","sequence":"additional","affiliation":[{"name":"WHO Collaborating Centre for Research and Training in Mental Health and Service Evaluation, Department of Neuroscience, Biomedicine and Movement Sciences, Section of Psychiatry University of Verona  Verona Italy"},{"name":"Institute of Social and Preventive Medicine University of Bern  Bern Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicole","family":"Ochsenbein\u2010Koelble","sequence":"additional","affiliation":[{"name":"Department of Obstetrics University Hospital of Zurich  Zurich Switzerland"},{"name":"University of Z\u00fcrich  Z\u00fcrich Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sebastian","family":"Olbrich","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Psychotherapy and Psychosomatics, Hospital of Psychiatry University of Zurich  Zurich Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Corrado","family":"Barbui","sequence":"additional","affiliation":[{"name":"WHO Collaborating Centre for Research and Training in Mental Health and Service Evaluation, Department of Neuroscience, Biomedicine and Movement Sciences, Section of Psychiatry University of Verona  Verona Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erich","family":"Seifritz","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Psychotherapy and Psychosomatics, Hospital of Psychiatry University of Zurich  Zurich Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,6,7]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra1513247"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12884-020-02971-3"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/birt.12543"},{"key":"e_1_2_12_5_1","unstructured":"Centers for Disease Control and Prevention (CDC). 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