{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T00:43:04Z","timestamp":1787013784373,"version":"build-2736575974"},"reference-count":42,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2023,7,27]],"date-time":"2023-07-27T00:00:00Z","timestamp":1690416000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100005416","name":"Norges Forskningsr\u00e5d","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005416","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Psychiatr Scand"],"published-print":{"date-parts":[[2023,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Psychotic\u2010like experiences (PLE) have been associated with the subsequent emergence of psychotic disorders as well as several other domains of psychopathology. In this twin study, we estimated the genetic and environmental correlations between PLE and 10 personality disorders (PD).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Diagnoses of 10 PDs according to the Diagnostic and Statistical Manual of Mental Disorders (DSM\u2010IV) and PLE from the Composite International Diagnostic Interview (CIDI) were retrieved for 2793 young adult twins from the Norwegian Twin Registry. Risk for having a PD and PLEs was modeled using item response theory. Biometric twin models were fitted to estimate the genetic and environmental correlations between PDs and PLEs. Co\u2010twin control analysis was performed to estimate additional within\u2010family risk for PLEs when having a PD.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Phenotypic overlap between PDs and PLEs ranged from 14% to 44% in males and from 11% to 39% in females, with the highest overlap for borderline PD in both sexes. In general, we found higher genetic correlations (\n                      <jats:italic>r<\/jats:italic>\n                      \u2009=\u20090.14\u20130.72) than environmental correlations (\n                      <jats:italic>r<\/jats:italic>\n                      \u2009=\u20090.06\u20130.28) between PDs and PLEs. The highest genetic correlations between PLE and PDs were found for borderline (\n                      <jats:italic>r<\/jats:italic>\n                      \u2009=\u20090.72), paranoid (\n                      <jats:italic>r<\/jats:italic>\n                      \u2009=\u20090.56), schizotypal (\n                      <jats:italic>r<\/jats:italic>\n                      \u2009=\u20090.56) and antisocial PD (r\u2009=\u20090.49).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>We found that the co\u2010occurrence between PDs and PLE is the best explained by shared genetic determinants, with minor contributions from environmental factors. Interestingly, borderline PD was highly genetically correlated with PLE, warranting molecular genetic studies of this association.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/acps.13596","type":"journal-article","created":{"date-parts":[[2023,7,27]],"date-time":"2023-07-27T05:40:30Z","timestamp":1690436430000},"page":"561-569","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Common genetic and environmental risk for personality disorders and psychotic\u2010like experiences in young adult twins"],"prefix":"10.1111","volume":"148","author":[{"given":"Martin","family":"Tesli","sequence":"first","affiliation":[{"name":"Department of Mental Disorders Norwegian Institute of Public Health  Oslo Norway"},{"name":"Centre for Research and Education in Forensic Psychiatry, Department of Mental Health and Addiction Oslo University Hospital  Oslo 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