{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T01:54:22Z","timestamp":1790906062555,"version":"4.1.0"},"reference-count":137,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T00:00:00Z","timestamp":1782172800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T00:00:00Z","timestamp":1782172800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acta Psychiatr Scand"],"published-print":{"date-parts":[[2026,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>\n                      People with severe mental illness (\n                      <jats:styled-content style=\"fixed-case\">SMIs<\/jats:styled-content>\n                      ) are at an increased risk of morbidity and reduced life expectancy. Obstructive sleep apnoea (\n                      <jats:styled-content style=\"fixed-case\">OSA<\/jats:styled-content>\n                      ), a prevalent but underdiagnosed condition in\n                      <jats:styled-content style=\"fixed-case\">SMIs<\/jats:styled-content>\n                      , may precipitate more physical health complications. This meta\u2010analysis aimed to estimate the prevalence of\n                      <jats:styled-content style=\"fixed-case\">OSA<\/jats:styled-content>\n                      and assess its risk in\n                      <jats:styled-content style=\"fixed-case\">SMIs<\/jats:styled-content>\n                      populations.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      We conducted a systematic review and meta\u2010analysis on studies reporting either diagnosis or high risk of\n                      <jats:styled-content style=\"fixed-case\">OSA<\/jats:styled-content>\n                      in bipolar disorder (\n                      <jats:styled-content style=\"fixed-case\">BD<\/jats:styled-content>\n                      ), schizophrenia (\n                      <jats:styled-content style=\"fixed-case\">SCZ<\/jats:styled-content>\n                      ), and major depressive disorder (\n                      <jats:styled-content style=\"fixed-case\">MDD<\/jats:styled-content>\n                      ). Databases were searched through January 2026. Pooled prevalence of\n                      <jats:styled-content style=\"fixed-case\">OSA<\/jats:styled-content>\n                      was calculated through a single\u2010group meta\u2010analysis, while odds ratios (\n                      <jats:styled-content style=\"fixed-case\">ORs<\/jats:styled-content>\n                      ) comparing\n                      <jats:styled-content style=\"fixed-case\">SMIs<\/jats:styled-content>\n                      and control groups were estimated by a two\u2010group meta\u2010analysis.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 47 articles were included in the meta\u2010analysis. The pooled prevalence of\n                      <jats:styled-content style=\"fixed-case\">OSA<\/jats:styled-content>\n                      in\n                      <jats:styled-content style=\"fixed-case\">SMIs<\/jats:styled-content>\n                      was 41.2%, largely influenced by clinical and sleep\u2010referral settings, with a 38.3% prevalence in\n                      <jats:styled-content style=\"fixed-case\">SCZ<\/jats:styled-content>\n                      , 38.2% in\n                      <jats:styled-content style=\"fixed-case\">MDD<\/jats:styled-content>\n                      and 35.6% in\n                      <jats:styled-content style=\"fixed-case\">BD<\/jats:styled-content>\n                      . Compared to healthy controls (\n                      <jats:styled-content style=\"fixed-case\">HCs<\/jats:styled-content>\n                      ) without psychiatric diagnosis, participants with\n                      <jats:styled-content style=\"fixed-case\">SMIs<\/jats:styled-content>\n                      had significantly higher odds of being diagnosed with\n                      <jats:styled-content style=\"fixed-case\">OSA<\/jats:styled-content>\n                      (\n                      <jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>\n                      \u2009=\u20096.96; 95%\n                      <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                      \u2009=\u20092.48, 19.51;\n                      <jats:italic>k<\/jats:italic>\n                      \u2009=\u20092;\n                      <jats:italic>p<\/jats:italic>\n                      \u2010value &lt;\u20090.001). High risk of\n                      <jats:styled-content style=\"fixed-case\">OSA<\/jats:styled-content>\n                      was present in 46.7% of\n                      <jats:styled-content style=\"fixed-case\">SMI<\/jats:styled-content>\n                      individuals.\n                      <jats:styled-content style=\"fixed-case\">BD<\/jats:styled-content>\n                      participants showed significantly higher excessive daytime sleepiness compared to\n                      <jats:styled-content style=\"fixed-case\">HCs<\/jats:styled-content>\n                      (\n                      <jats:styled-content style=\"fixed-case\">SMD<\/jats:styled-content>\n                      \u2009=\u20090.63; 95%\n                      <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                      \u2009=\u20090.28, 0.98;\n                      <jats:italic>k<\/jats:italic>\n                      \u2009=\u20092;\n                      <jats:italic>p<\/jats:italic>\n                      \u2010value &lt;\u20090.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      People with\n                      <jats:styled-content style=\"fixed-case\">SMIs<\/jats:styled-content>\n                      have a high prevalence of\n                      <jats:styled-content style=\"fixed-case\">OSA<\/jats:styled-content>\n                      and are at an increased risk of\n                      <jats:styled-content style=\"fixed-case\">OSA<\/jats:styled-content>\n                      compared to the general population. These findings highlight the considerable burden of\n                      <jats:styled-content style=\"fixed-case\">OSA<\/jats:styled-content>\n                      in\n                      <jats:styled-content style=\"fixed-case\">SMIs<\/jats:styled-content>\n                      and support the need for systematic assessment within psychiatric care settings.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/acps.70119","type":"journal-article","created":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T13:34:15Z","timestamp":1782221655000},"page":"322-341","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["The Prevalence of Obstructive Sleep Apnoea in Schizophrenia, Bipolar Disorder and Major Depressive Disorder: A Systematic Review With 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