{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,9]],"date-time":"2025-09-09T22:11:53Z","timestamp":1757455913194,"version":"3.41.0"},"reference-count":43,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2015,3,6]],"date-time":"2015-03-06T00:00:00Z","timestamp":1425600000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1"},{"start":{"date-parts":[[2015,3,6]],"date-time":"2015-03-06T00:00:00Z","timestamp":1425600000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions"}],"funder":[{"DOI":"10.13039\/100000002","name":"U.S. National Institutes of Health","doi-asserted-by":"crossref","award":["R01 DA013951"],"award-info":[{"award-number":["R01 DA013951"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"crossref","award":["F31 DA030891"],"award-info":[{"award-number":["F31 DA030891"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Addiction Biology"],"published-print":{"date-parts":[[2016,5]]},"DOI":"10.1111\/adb.12235","type":"journal-article","created":{"date-parts":[[2015,3,6]],"date-time":"2015-03-06T11:40:37Z","timestamp":1425642037000},"page":"530-546","source":"Crossref","is-referenced-by-count":11,"title":["Phenotype-dependent inhibition of glutamatergic transmission on nucleus accumbens medium spiny neurons by the abused inhalant toluene"],"prefix":"10.1111","volume":"21","author":[{"given":"Jacob T.","family":"Beckley","sequence":"first","affiliation":[{"name":"Department of Neuroscience; Medical University of South Carolina; Charleston SC USA"},{"name":"Center for Drug and Alcohol Programs; Department of Psychiatry; Medical University of South Carolina; Charleston SC USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patrick K.","family":"Randall","sequence":"additional","affiliation":[{"name":"Center for Drug and Alcohol Programs; Department of Psychiatry; Medical University of South Carolina; Charleston SC USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rachel J.","family":"Smith","sequence":"additional","affiliation":[{"name":"Department of Neuroscience; Medical University of South Carolina; Charleston SC USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Benjamin A.","family":"Hughes","sequence":"additional","affiliation":[{"name":"Department of Neuroscience; Medical University of South Carolina; Charleston SC USA"},{"name":"Center for Drug and Alcohol Programs; Department of Psychiatry; Medical University of South Carolina; Charleston SC USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter W.","family":"Kalivas","sequence":"additional","affiliation":[{"name":"Department of Neuroscience; Medical University of South Carolina; Charleston SC USA"},{"name":"Center for Drug and Alcohol Programs; Department of Psychiatry; Medical University of South Carolina; Charleston SC USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John J.","family":"Woodward","sequence":"additional","affiliation":[{"name":"Department of Neuroscience; Medical University of South Carolina; Charleston SC USA"},{"name":"Center for Drug and Alcohol Programs; Department of Psychiatry; Medical University of South Carolina; Charleston SC USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,3,6]]},"reference":[{"key":"10.1111\/adb.12235-BIB0001|adb12235-cit-0001","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1016\/j.mri.2011.11.001","article-title":"Partial least squares for discrimination in fMRI data","volume":"30","author":"Andersen","year":"2012","journal-title":"Magn Reson Imaging"},{"key":"10.1111\/adb.12235-BIB0002|adb12235-cit-0002","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1007\/s00213-014-3651-x","article-title":"Striatal dopamine dynamics in mice following acute and repeated toluene exposure","volume":"232","author":"Apawu","year":"2014","journal-title":"Psychopharmacology (Berl)"},{"key":"10.1111\/adb.12235-BIB0003|adb12235-cit-0003","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1002\/(SICI)1096-9861(20000228)418:1<22::AID-CNE2>3.0.CO;2-Q","article-title":"Phenotypical characterization of the neurons expressing the D1 and D2 dopamine receptors in the monkey striatum","volume":"418","author":"Aubert","year":"2000","journal-title":"J Comp Neurol"},{"key":"10.1111\/adb.12235-BIB0004|adb12235-cit-0004","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/j.neuroscience.2004.08.040","article-title":"Alterations in glutamatergic and gabaergic ion channel activity in hippocampal neurons following exposure to the abused inhalant toluene","volume":"130","author":"Bale","year":"2005","journal-title":"Neuroscience"},{"key":"10.1111\/adb.12235-BIB0005|adb12235-cit-0005","doi-asserted-by":"crossref","first-page":"1531","DOI":"10.1038\/npp.2011.38","article-title":"The abused inhalant toluene differentially modulates excitatory and inhibitory synaptic transmission in deep-layer neurons of the medial prefrontal cortex","volume":"36","author":"Beckley","year":"2011","journal-title":"Neuropsychopharmacology"},{"key":"10.1111\/adb.12235-BIB0006|adb12235-cit-0006","doi-asserted-by":"crossref","first-page":"2555","DOI":"10.1038\/npp.2013.206","article-title":"Volatile solvents as drugs of abuse: focus on the cortico-mesolimbic circuitry","volume":"38","author":"Beckley","year":"2013","journal-title":"Neuropsychopharmacology"},{"key":"10.1111\/adb.12235-BIB0007|adb12235-cit-0007","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/j.ejphar.2003.11.068","article-title":"Intravenous self-administration of abused solvents and anesthetics in mice","volume":"485","author":"Blokhina","year":"2004","journal-title":"Eur J Pharmacol"},{"key":"10.1111\/adb.12235-BIB0008|adb12235-cit-0008","doi-asserted-by":"crossref","first-page":"632","DOI":"10.1038\/nn.3369","article-title":"Strengthening the accumbal indirect pathway promotes resilience to compulsive cocaine use","volume":"16","author":"Bock","year":"2013","journal-title":"Nat Neurosci"},{"key":"10.1111\/adb.12235-BIB2001|adb12235-cit-2001","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1111\/j.1460-9568.2008.06038.x","article-title":"Differential electrophysiological properties of dopamine D1 and D2 receptor-containing striatal medium-sized spiny neurons","volume":"27","author":"Cepeda","year":"2008","journal-title":"Eur J Neurosci"},{"key":"10.1111\/adb.12235-BIB0009|adb12235-cit-0009","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1016\/S0022-3565(24)37592-5","article-title":"Effects of the abused solvent toluene on recombinant N-methyl-D-aspartate and non-N-methyl-D-aspartate receptors expressed in Xenopus oocytes","volume":"286","author":"Cruz","year":"1998","journal-title":"J Pharmacol Exp Ther"},{"key":"10.1111\/adb.12235-BIB0010|adb12235-cit-0010","doi-asserted-by":"crossref","first-page":"1303","DOI":"10.1038\/sj.bjp.0703666","article-title":"Effects of volatile solvents on recombinant N-methyl-D-aspartate receptors expressed in Xenopus oocytes","volume":"131","author":"Cruz","year":"2000","journal-title":"Br J Pharmacol"},{"key":"10.1111\/adb.12235-BIB0011|adb12235-cit-0011","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1038\/nature11846","article-title":"Concurrent activation of striatal direct and indirect pathways during action initiation","volume":"494","author":"Cui","year":"2013","journal-title":"Nature"},{"key":"10.1111\/adb.12235-BIB0012|adb12235-cit-0012","doi-asserted-by":"crossref","first-page":"249","DOI":"10.3727\/000000001783992498","article-title":"Exploring relationships in gene expressions: a partial least squares approach","volume":"9","author":"Datta","year":"2001","journal-title":"Gene Expr"},{"key":"10.1111\/adb.12235-BIB0013|adb12235-cit-0013","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.brainres.2006.03.031","article-title":"Effects of the abused inhalant toluene on ethanol-sensitive potassium channels expressed in oocytes","volume":"1087","author":"Del Re","year":"2006","journal-title":"Brain Res"},{"key":"10.1111\/adb.12235-BIB0014|adb12235-cit-0014","doi-asserted-by":"crossref","first-page":"5274","DOI":"10.1073\/pnas.85.14.5274","article-title":"Drugs abused by humans preferentially increase synaptic dopamine concentrations in the mesolimbic system of freely moving rats","volume":"85","author":"Di Chiara","year":"1988","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1111\/adb.12235-BIB0015|adb12235-cit-0015","doi-asserted-by":"crossref","first-page":"3461","DOI":"10.1097\/00001756-200011090-00013","article-title":"Mice are not little rats: species differences in a one-day water maze task","volume":"11","author":"Frick","year":"2000","journal-title":"Neuroreport"},{"key":"10.1111\/adb.12235-BIB0016|adb12235-cit-0016","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1146\/annurev.ne.15.030192.001441","article-title":"The neostriatal mosaic: multiple levels of compartmental organization in the basal ganglia","volume":"15","author":"Gerfen","year":"1992","journal-title":"Annu Rev Neurosci"},{"key":"10.1111\/adb.12235-BIB2002|adb12235-cit-2002","doi-asserted-by":"crossref","first-page":"1519","DOI":"10.1038\/nn.2685","article-title":"Postsynaptic TRPV1 triggers cell type-specific long-term depression in the nucleus accumbens","volume":"13","author":"Grueter","year":"2010","journal-title":"Nat Neurosci"},{"key":"10.1111\/adb.12235-BIB0017|adb12235-cit-0017","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1038\/npp.2009.129","article-title":"The reward circuit: linking primate anatomy and human imaging","volume":"35","author":"Haber","year":"2010","journal-title":"Neuropsychopharmacology"},{"key":"10.1111\/adb.12235-BIB0018|adb12235-cit-0018","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1038\/npp.2008.174","article-title":"Metabolomics: a global biochemical approach to the study of central nervous system diseases","volume":"34","author":"Kaddurah-Daouk","year":"2009","journal-title":"Neuropsychopharmacology"},{"key":"10.1111\/adb.12235-BIB2003|adb12235-cit-2003","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1523\/JNEUROSCI.4287-10.2011","article-title":"Dopamine D2 receptor overexpression alters behavior and physiology in Drd2-EGFP mice","volume":"31","author":"Kramer","year":"2011","journal-title":"J Neurosci"},{"key":"10.1111\/adb.12235-BIB0019|adb12235-cit-0019","doi-asserted-by":"crossref","first-page":"816","DOI":"10.1038\/nn.3100","article-title":"Distinct roles for direct and indirect pathway striatal neurons in reinforcement","volume":"15","author":"Kravitz","year":"2012","journal-title":"Nat Neurosci"},{"key":"10.1111\/adb.12235-BIB2004|adb12235-cit-2004","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1038\/nature05506","article-title":"Endocannabinoid-mediated rescue of striatal LTD and motor deficits in Parkinson's disease models","volume":"445","author":"Kreitzer","year":"2007","journal-title":"Nature"},{"key":"10.1111\/adb.12235-BIB0020|adb12235-cit-0020","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1073\/pnas.87.1.230","article-title":"Dopamine receptor gene expression by enkephalin neurons in rat forebrain","volume":"87","author":"Le Moine","year":"1990","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1111\/adb.12235-BIB0021|adb12235-cit-0021","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/j.drugalcdep.2006.03.013","article-title":"Concentration-dependent conditioned place preference to inhaled toluene vapors in rats","volume":"85","author":"Lee","year":"2006","journal-title":"Drug Alcohol Depend"},{"key":"10.1111\/adb.12235-BIB0022|adb12235-cit-0022","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1016\/j.chroma.2006.11.091","article-title":"Quantitative structure-retention relationship studies with immobilized artificial membrane chromatography II: partial least squares regression","volume":"1140","author":"Li","year":"2007","journal-title":"J Chromatogr A"},{"key":"10.1111\/adb.12235-BIB0023|adb12235-cit-0023","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1016\/S0306-4522(97)00327-8","article-title":"Expression of D1 receptor, D2 receptor, substance P and enkephalin messenger RNAs in the neurons projecting from the nucleus accumbens","volume":"82","author":"Lu","year":"1998","journal-title":"Neuroscience"},{"key":"10.1111\/adb.12235-BIB0024|adb12235-cit-0024","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1038\/bjp.2008.76","article-title":"Inhalant abuse among adolescents: neurobiological considerations","volume":"154","author":"Lubman","year":"2008","journal-title":"Br J Pharmacol"},{"key":"10.1111\/adb.12235-BIB0025|adb12235-cit-0025","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1042\/AN20110063","article-title":"Regional and cell-type-specific effects of DAMGO on striatal D1 and D2 dopamine receptor-expressing medium-sized spiny neurons","volume":"4","author":"Ma","year":"2012","journal-title":"ASN Neuro"},{"key":"10.1111\/adb.12235-BIB0026|adb12235-cit-0026","doi-asserted-by":"crossref","first-page":"9119","DOI":"10.1523\/JNEUROSCI.0224-12.2012","article-title":"A comparison of striatal-dependent behaviors in wild-type and hemizygous Drd1a and Drd2 BAC transgenic mice","volume":"32","author":"Nelson","year":"2012","journal-title":"J Neurosci"},{"key":"10.1111\/adb.12235-BIB0027|adb12235-cit-0027","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1016\/0165-0173(94)00008-D","article-title":"Functional anatomy of the basal ganglia. II. The place of subthalamic nucleus and external pallidum in basal ganglia circuitry","volume":"20","author":"Parent","year":"1995","journal-title":"Brain Res Brain Res Rev"},{"key":"10.1111\/adb.12235-BIB0028|adb12235-cit-0028","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/j.alcohol.2012.01.002","article-title":"A review of the interactions between alcohol and the endocannabinoid system: implications for alcohol dependence and future directions for research","volume":"46","author":"Pava","year":"2012","journal-title":"Alcohol"},{"key":"10.1111\/adb.12235-BIB0029|adb12235-cit-0029","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1016\/j.aca.2007.09.014","article-title":"Review on modelling aspects in reversed-phase liquid chromatographic quantitative structure-retention relationships","volume":"602","author":"Put","year":"2007","journal-title":"Anal Chim Acta"},{"key":"10.1111\/adb.12235-BIB0030|adb12235-cit-0030","doi-asserted-by":"crossref","first-page":"8384","DOI":"10.1073\/pnas.122149199","article-title":"Endogenous cannabinoids mediate long-term synaptic depression in the nucleus accumbens","volume":"99","author":"Robbe","year":"2002","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1111\/adb.12235-BIB0031|adb12235-cit-0031","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1007\/s11306-005-4810-1","article-title":"Metabolomic analysis and signatures in motor neuron disease","volume":"1","author":"Rozen","year":"2005","journal-title":"Metabolomics"},{"key":"10.1111\/adb.12235-BIB0032|adb12235-cit-0032","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1126\/science.1231059","article-title":"Interactions between the nucleus accumbens and auditory cortices predict music reward value","volume":"403","author":"Salimpoor","year":"2013","journal-title":"Science"},{"key":"10.1111\/adb.12235-BIB0033|adb12235-cit-0033","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1038\/npp.2009.93","article-title":"Cortico-basal ganglia reward network: microcircuitry","volume":"35","author":"Sesack","year":"2010","journal-title":"Neuropsychopharmacology"},{"key":"10.1111\/adb.12235-BIB0034|adb12235-cit-0034","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1016\/j.conb.2013.01.026","article-title":"Cocaine-induced adaptations in D1 and D2 accumbens projection neurons (a dichotomy not necessarily synonymous with direct and indirect pathways)","volume":"23","author":"Smith","year":"2013","journal-title":"Curr Opin Neurobiol"},{"key":"10.1111\/adb.12235-BIB0035|adb12235-cit-0035","doi-asserted-by":"crossref","first-page":"14484","DOI":"10.1523\/JNEUROSCI.1768-09.2009","article-title":"Adult-born hippocampal neurons are more numerous, faster maturing, and more involved in behavior in rats than in mice","volume":"29","author":"Snyder","year":"2009","journal-title":"J Neurosci"},{"key":"10.1111\/adb.12235-BIB0036|adb12235-cit-0036","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/j.chemolab.2014.08.005","article-title":"Interpretation of variable importance in partial least squares with significance multivariate correlation (sMC)","volume":"138","author":"Tran","year":"2014","journal-title":"Chemometr Intell Lab Syst"},{"key":"10.1111\/adb.12235-BIB0037|adb12235-cit-0037","doi-asserted-by":"crossref","first-page":"2249","DOI":"10.1038\/npp.2010.99","article-title":"Deficiency in endocannabinoid signaling in the nucleus accumbens induced by chronic unpredictable stress","volume":"35","author":"Wang","year":"2010","journal-title":"Neuropsychopharmacology"},{"key":"10.1111\/adb.12235-BIB0038|adb12235-cit-0038","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1289\/ehp.793039","article-title":"Behavioral toxicology of carbon disulfide and toluene","volume":"30","author":"Weiss","year":"1979","journal-title":"Environ Health Perspect"},{"key":"10.1111\/adb.12235-BIB0039|adb12235-cit-0039","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1038\/nrn1406","article-title":"Dopamine, learning and motivation","volume":"5","author":"Wise","year":"2004","journal-title":"Nat Rev Neurosci"}],"container-title":["Addiction Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fadb.12235","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fadb.12235","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/onlinelibrary.wiley.com\/wol1\/doi\/10.1111\/adb.12235\/fullpdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,20]],"date-time":"2025-05-20T19:31:31Z","timestamp":1747769491000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/adb.12235"}},"subtitle":["Toluene and D2 MSN plasticity"],"short-title":[],"issued":{"date-parts":[[2015,3,6]]},"references-count":43,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2016,5]]}},"URL":"https:\/\/doi.org\/10.1111\/adb.12235","archive":["Portico"],"relation":{},"ISSN":["1355-6215"],"issn-type":[{"type":"print","value":"1355-6215"}],"subject":[],"published":{"date-parts":[[2015,3,6]]}}}