{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T01:53:57Z","timestamp":1790819637919,"version":"4.1.0"},"reference-count":49,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2015,12,21]],"date-time":"2015-12-21T00:00:00Z","timestamp":1450656000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"The European Regional Development Fund, European Commission INTERREG IVA","award":["4096"],"award-info":[{"award-number":["4096"]}]},{"name":"Le Conseil r\u00e9gional de Picardie"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Addiction Biology"],"published-print":{"date-parts":[[2017,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Binge drinking is associated with impaired cognitive functioning, but the relationship of cognitive impairments and white matter integrity is less known. We used diffusion tensor imaging (DTI) to investigate the relationships of binge drinking, whole brain white matter integrity and cognitive performance during young adulthood (18 to 25\u2009years), a period of continued brain development in two sessions 1\u2009year apart. Binge drinkers (<jats:italic>n<\/jats:italic>\u2009=\u200920) and non\u2010binge drinkers (<jats:italic>n<\/jats:italic>\u2009=\u200920) underwent DTI and completed measures of spatial working memory and motor impulsivity. Fractional anisotropy (FA), a measure derived from DTI, was estimated from whole brain and from five segments of the corpus callosum (CC): prefrontal, premotor\/supplementary motor, motor, (SMA) sensory and parietal\/temporal\/occipital (PTO). FA was lower for binge than for non\u2010binge men but not women at Session 1 and 2 for all measurements except for FA in the motor segment, which was significantly increased from Session 1 to Session 2. Lower FA in the prefrontal and PTO CC segments was associated with higher binge score, whereas lower FA in all five segments was associated with greater drug use in men and worse spatial working memory both in men and women. These findings extend the literature by showing that in early adulthood, binge drinking and drug use are linked with degradations in neural white matter and that compromised white matter at this period of brain development is linked with impaired cognitive functioning.<\/jats:p>","DOI":"10.1111\/adb.12332","type":"journal-article","created":{"date-parts":[[2015,12,21]],"date-time":"2015-12-21T06:15:57Z","timestamp":1450678557000},"page":"490-501","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":48,"title":["Altered white matter integrity in whole brain and segments of corpus callosum, in young social drinkers with binge drinking pattern"],"prefix":"10.1111","volume":"22","author":[{"given":"Kathleen W.","family":"Smith","sequence":"first","affiliation":[{"name":"Behavioural and Clinical Neuroscience, School of Psychology University of Sussex  Brighton UK"},{"name":"Groupe de Recherche sur l'Alcool et les Pharmacod\u00e9pendances, Equipe R\u00e9gion INSERM 24 Universit\u00e9 de Picardie Jules Verne  Amiens France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabien","family":"Gierski","sequence":"additional","affiliation":[{"name":"Cognition, Health, Socialization Laboratory (C2S, EA6291) University of Reims  Reims France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Judith","family":"Andre","sequence":"additional","affiliation":[{"name":"Groupe de Recherche sur l'Alcool et les Pharmacod\u00e9pendances, Equipe R\u00e9gion INSERM 24 Universit\u00e9 de Picardie Jules Verne  Amiens France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicholas G.","family":"Dowell","sequence":"additional","affiliation":[{"name":"Clinical Imaging Sciences Centre, Brighton and Sussex Medical School University of Sussex  Brighton UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mara","family":"Cercignani","sequence":"additional","affiliation":[{"name":"Clinical Imaging Sciences Centre, Brighton and Sussex Medical School University of Sussex  Brighton UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Micka\u00ebl","family":"Naassila","sequence":"additional","affiliation":[{"name":"Groupe de Recherche sur l'Alcool et les Pharmacod\u00e9pendances, Equipe R\u00e9gion INSERM 24 Universit\u00e9 de Picardie Jules Verne  Amiens France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Theodora","family":"Duka","sequence":"additional","affiliation":[{"name":"Behavioural and Clinical Neuroscience, School of Psychology University of Sussex  Brighton UK"},{"name":"Clinical Imaging Sciences Centre, Brighton and Sussex Medical School University of Sussex  Brighton UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,12,21]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/cercor\/bhp282"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/cercor\/bhi062"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainres.2010.12.051"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1530-0277.2012.01920.x"},{"key":"e_1_2_7_6_1","volume-title":"Manual for the Beck Depression Inventory\u2013II","author":"Beck AT","year":"1996"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.10609"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.20281"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1369-1600.2007.00095.x"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1530-0277.2007.00603.x"},{"key":"e_1_2_7_11_1","unstructured":"European Union: Directorate General Communication(2010).Eurobarometer 72.3: EUcitizens' attitudes towards alcohol. Brussels Belgium: TNS Opinion & Social Special Eurobarometer 331. Retrieved from:http:\/\/ec.europa.eu\/public_opinion\/archives\/ebs\/ebs_331_en.pdf"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bandc.2008.01.009"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.2001.tb05772.x"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2007.07.043"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0402680101"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00429-009-0238-0"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1093\/cercor\/bhr246"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2006.05.044"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.A2785"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ntt.2009.07.006"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pscychresns.2013.07.014"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.3390\/brainsci3010396"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0038272"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2011.03.016"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2007.12.053"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1530-0277.2009.00953.x"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1530-0277.2007.00602.x"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ntt.2006.10.010"},{"key":"e_1_2_7_29_1","doi-asserted-by":"publisher","DOI":"10.2466\/pr0.1978.43.3.803"},{"key":"e_1_2_7_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2010.11.029"},{"key":"e_1_2_7_31_1","volume-title":"The National Adult Reading Test (NART)","author":"Nelson H","year":"1982"},{"key":"e_1_2_7_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsych.2008.10.039"},{"key":"e_1_2_7_33_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.1910360612"},{"key":"e_1_2_7_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pbb.2009.05.015"},{"key":"e_1_2_7_35_1","doi-asserted-by":"publisher","DOI":"10.1002\/hbm.20431"},{"key":"e_1_2_7_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mri.2006.03.012"},{"key":"e_1_2_7_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2013.12.044"},{"key":"e_1_2_7_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2006.02.024"},{"key":"e_1_2_7_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2004.07.051"},{"key":"e_1_2_7_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2008.03.061"},{"key":"e_1_2_7_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2005.03.016"},{"key":"e_1_2_7_42_1","doi-asserted-by":"publisher","DOI":"10.1006\/nimg.2002.1267"},{"key":"e_1_2_7_43_1","volume-title":"Spielberger State\u2010trait Anxiety Inventory","author":"Spielberger CD","year":"1970"},{"key":"e_1_2_7_44_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1530-0277.2011.01527.x"},{"key":"e_1_2_7_45_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11065-010-9148-4"},{"key":"e_1_2_7_46_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.drugalcdep.2010.02.004"},{"key":"e_1_2_7_47_1","doi-asserted-by":"publisher","DOI":"10.1093\/alcalc\/37.2.187"},{"key":"e_1_2_7_48_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.ALC.0000156453.05028.F5"},{"key":"e_1_2_7_49_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00213-002-1281-1"},{"key":"e_1_2_7_50_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrm.21965"}],"container-title":["Addiction Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fadb.12332","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fadb.12332","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/adb.12332","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,18]],"date-time":"2023-09-18T11:56:44Z","timestamp":1695038204000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/adb.12332"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,12,21]]},"references-count":49,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2017,3]]}},"alternative-id":["10.1111\/adb.12332"],"URL":"https:\/\/doi.org\/10.1111\/adb.12332","archive":["Portico"],"relation":{},"ISSN":["1355-6215","1369-1600"],"issn-type":[{"value":"1355-6215","type":"print"},{"value":"1369-1600","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,12,21]]},"assertion":[{"value":"2015-02-19","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2015-10-21","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2015-12-21","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}