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However, there is much less information on RPE in individuals at risk of alcohol misuse, prior to neurobiological adaptations that might result from sustained alcohol use. Here, participants (mean age 23.77 years, range 18\u201032 years) performed the electrophysiological monetary incentive delay task. This task involved responding to a target stimulus following reward incentive cues to win, or avoid losing, the cued reward while brain activity was recorded under 64\u2010channel EEG. The Alcohol Use Disorders Identification Test (AUDIT) was used to quantify at\u2010risk alcohol use, with high (n = 22, mean AUDIT score: 13.82) and low (n = 22, mean AUDIT score: 5.77) alcohol use groups. Trial\u2010by\u2010trial RPEs were estimated using a Rescorla\u2010Wagner reinforcement model based on behavioral data. A single\u2010trial analysis revealed that the feedback\u2010related negativity (FRN) and feedback P3 (fb\u2010P3) event\u2010related potential components were significantly modulated by RPEs. There was increased RPE\u2010related fb\u2010P3 amplitude for those in the high alcohol use group. Next, the mean amplitude of ERPs elicited by positive and negative RPEs were compared between groups. We found that high alcohol use participants had attenuated FRN amplitude in contrast with low alcohol use participants for both positive and negative RPEs but enhanced fb\u2010P3 for both positive and negative RPE. These results, with differences in RPE in an at\u2010risk group, suggest that RPE a potential vulnerability marker for alcohol use disorder.<\/jats:p>","DOI":"10.1111\/adb.12873","type":"journal-article","created":{"date-parts":[[2020,1,24]],"date-time":"2020-01-24T06:31:38Z","timestamp":1579847498000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Aberrant reward prediction errors in young adult at\u2010risk alcohol users"],"prefix":"10.1111","volume":"26","author":[{"given":"Zhipeng","family":"Cao","sequence":"first","affiliation":[{"name":"School of Psychology University College Dublin  Dublin Ireland"},{"name":"Institute of Neuroscience Trinity College Dublin  Dublin Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marc","family":"Bennett","sequence":"additional","affiliation":[{"name":"School of Psychology Trinity College Dublin  Dublin Ireland"},{"name":"Medical Research Council, 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