{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T09:17:11Z","timestamp":1791883031544,"version":"4.3.4"},"reference-count":93,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2020,4,14]],"date-time":"2020-04-14T00:00:00Z","timestamp":1586822400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000027","name":"National Institute on Alcohol Abuse and Alcoholism","doi-asserted-by":"publisher","award":["K24AA025704"],"award-info":[{"award-number":["K24AA025704"]}],"id":[{"id":"10.13039\/100000027","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Addiction Biology"],"published-print":{"date-parts":[[2021,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>In March 2019, a scientific meeting was held at the University of California, Los Angeles (UCLA) Luskin Center to discuss approaches to expedite the translation of neurobiological insights to advances in the treatment of alcohol use disorder (AUD). A guiding theme that emerged was that while translational research in AUD is clearly a challenge, it is also a field ripe with opportunities. Herein, we seek to summarize and disseminate the recommendations for the future of translational AUD research using four sections. First, we briefly review the current landscape of AUD treatment including the available evidence\u2010based treatments and their uptake in clinical settings. Second, we discuss AUD treatment development efforts from a translational science viewpoint. We review current hurdles to treatment development as well as opportunities for mechanism\u2010informed treatment. Third, we consider models of translational science and public health impact. Together, these critical insights serve as the bases for a series of recommendations and future directions. Towards the goal of improving clinical care and population health for AUD, scientists are tasked with bolstering the clinical applicability of their research findings so as to expedite the translation of knowledge into patient care.<\/jats:p>","DOI":"10.1111\/adb.12903","type":"journal-article","created":{"date-parts":[[2021,2,20]],"date-time":"2021-02-20T04:59:11Z","timestamp":1613797151000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":44,"title":["The future of translational research on alcohol use disorder"],"prefix":"10.1111","volume":"26","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5734-9444","authenticated-orcid":false,"given":"Lara A.","family":"Ray","sequence":"first","affiliation":[{"name":"Department of Psychology University of California Los Angeles  Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erica N.","family":"Grodin","sequence":"additional","affiliation":[{"name":"Department of Psychology University of California Los Angeles  Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7284-8754","authenticated-orcid":false,"given":"Lorenzo","family":"Leggio","sequence":"additional","affiliation":[{"name":"Section on Clinical Psychoneuroendocrinology and Neuropsychopharmacology, National Institute on Alcohol Abuse and Alcoholism Division of Intramural Clinical and Biological Research and National Institute on Drug Abuse Intramural Research Program, National Institutes of Health, Bethesda, MD; Medication Development Program, National Institute on Drug Abuse Intramural Research Program, National Institutes of Health, Baltimore, MD; Center for Alcohol and Addiction Studies, Department of Behavioral and..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anita J.","family":"Bechtholt","sequence":"additional","affiliation":[{"name":"Division of Treatment and Recovery Research, National Institutes of Health National Institute on Alcohol Abuse and Alcoholism  Bethesda Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Howard","family":"Becker","sequence":"additional","affiliation":[{"name":"Charleston Alcohol Research Center, Department of Psychiatry and Behavioral Science; Department of Neuroscience Medical University of South Carolina; Ralph H. Johnson VA Medical Center  Charleston South Carolina USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah W.","family":"Feldstein Ewing","sequence":"additional","affiliation":[{"name":"Department of Child and Adolescent Psychiatry Oregon Health and Science University  Portland Oregon USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James David","family":"Jentsch","sequence":"additional","affiliation":[{"name":"Department of Psychology Binghamton University  Binghamton New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea C.","family":"King","sequence":"additional","affiliation":[{"name":"Department of Psychiatry and Behavioral Neuroscience University of Chicago  Chicago Illinois USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barbara J.","family":"Mason","sequence":"additional","affiliation":[{"name":"Pearson Center for Alcoholism and Addiction Research The Scripps Research Institute  San 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