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Some evidence suggests that a period of isolation might have led to a spike in alcohol misuse, and in the case of patients with alcohol use disorder (AUD), social isolation can favour lapse and relapse. The aim of our position paper is to provide specialists in the alcohol addiction field, in psychopharmacology, gastroenterology and in internal medicine, with appropriate tools to better manage patients with AUD and COVID\u201019,considering some important topics: (a) the susceptibility of AUD patients to infection; (b) the pharmacological interaction between medications used to treat AUD and to treat COVID\u201019; (c) the reorganization of the Centre for Alcohol Addiction Treatment for the management of AUD patients in the COVID\u201019 era (group activities, telemedicine, outpatients treatment, alcohol\u2010related liver disease and liver transplantation, collecting samples); (d) AUD and SARS\u2010CoV\u20102 vaccination. Telemedicine\/telehealth will undoubtedly be useful\/practical tools even though it remains at an elementary level; the contribution of the family and of caregivers in the management of AUD patients will play a significant role; the multidisciplinary intervention involving experts in the treatment of AUD with specialists in the treatment of COVID\u201019 disease will need implementation. 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