{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,5]],"date-time":"2026-04-05T04:57:57Z","timestamp":1775365077241,"version":"3.50.1"},"reference-count":68,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2021,12,16]],"date-time":"2021-12-16T00:00:00Z","timestamp":1639612800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Addiction Biology"],"published-print":{"date-parts":[[2022,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Studies have shown that internet gaming disorder (IGD) has the potential to be a type of addiction; however, direct comparisons (similarities and differences) between IGD and traditional addictions remain scarce, especially at the neuroimaging level. Resting\u2010state functional magnetic resonance imaging (fMRI) data were collected from 92 individuals with IGD, 96 individuals with tobacco use disorders (TUDs) and 107 individuals who served as healthy controls (HCs). Independent component analysis (ICA) was performed to explore the similarities and differences among these three groups; Granger causality analysis (GCA) was further performed based on the ICA results to determine potential neural features underlying the differences and similarities among the groups. The ICA results indicated significant differences in the subcortical network and cerebellar network. GCA results found that significant differences in bilateral caudate among three groups, and the efferents of dorsal frontostriatal circuit showed significant differences in insula among three groups, whereas efferents of ventral frontostriatal circuit showed significant differences in the medial prefrontal cortex (mPFC). Two kinds of addiction showed differences in thalamus and frontostriatal circuits, and similar changes found in cerebellum and mPFC regions. It suggested that addiction disorders have psychopathology features, and the craving and reward dysfunctions may be the key reasons. Although both substance addiction and behaviour addiction showed craving dysfunction in cerebellum, however, the key reward dysfunction of substance addiction was found in subcortical regions, whereas behaviour addiction located in cortical regions.<\/jats:p>","DOI":"10.1111\/adb.13119","type":"journal-article","created":{"date-parts":[[2021,12,16]],"date-time":"2021-12-16T09:36:38Z","timestamp":1639647398000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Similarities and differences between internet gaming disorder and tobacco use disorder: A large\u2010scale network study"],"prefix":"10.1111","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0573-2679","authenticated-orcid":false,"given":"Yan\u2010Bin","family":"Zheng","sequence":"first","affiliation":[{"name":"Centre for Cognition and Brain disorders The Affiliated Hospital of Hangzhou Normal University  Hangzhou China"},{"name":"Institute of Psychological Science Hangzhou Normal University  Hangzhou China"},{"name":"Zhejiang Key Laboratory for Research in Assessment of Cognitive Impairments Hangzhou Normal University  Hangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hao\u2010Hao","family":"Dong","sequence":"additional","affiliation":[{"name":"Department of Psychology Zhejiang Normal University  Zhejiang China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Min","family":"Wang","sequence":"additional","affiliation":[{"name":"Institute of Psychological Science Hangzhou Normal University  Hangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Weiran","family":"Zhou","sequence":"additional","affiliation":[{"name":"Centre for Cognition and Brain disorders The Affiliated Hospital of Hangzhou Normal University  Hangzhou China"},{"name":"Institute of Psychological Science Hangzhou Normal University  Hangzhou China"},{"name":"Zhejiang Key Laboratory for Research in Assessment of Cognitive Impairments Hangzhou Normal University  Hangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiao","family":"Lin","sequence":"additional","affiliation":[{"name":"National Clinical Research Center for Mental Disorders Peking University Sixth Hospital  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8813-8730","authenticated-orcid":false,"given":"Guang\u2010Heng","family":"Dong","sequence":"additional","affiliation":[{"name":"Centre for Cognition and Brain disorders The Affiliated Hospital of Hangzhou Normal University  Hangzhou China"},{"name":"Institute of Psychological Science Hangzhou Normal University  Hangzhou China"},{"name":"Zhejiang Key Laboratory for Research in Assessment of Cognitive Impairments Hangzhou Normal University  Hangzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,12,16]]},"reference":[{"issue":"1","key":"e_1_2_10_2_1","article-title":"Different resting\u2010state functional connectivity alterations in smokers and nonsmokers with Internet gaming addiction","volume":"2014","author":"Chen X","year":"2014","journal-title":"Biomed Res Int"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpsychires.2014.07.005"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11920-015-0610-0"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-clinpsy-032816-045120"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/add.12162"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/scan\/nsy084"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1038\/s42003\u2010021\u201002395\u20105"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/ADM.0b013e318233d637"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/adb.12713"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pnpbp.2015.02.004"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/adb.13046"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1038\/tp.2015.124"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0059902"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1017\/S1092852917000360"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.addbeh.2014.09.006"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1089\/brain.2011.0008"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/adb.12985"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pnpbp.2020.110154"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/adb.12348"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/adb.13076"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1002\/hbm.23153"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1002\/hbm.23153"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpsc.2017.01.002"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1002\/hbm.23690"},{"issue":"288","key":"e_1_2_10_26_1","first-page":"1","article-title":"Internet addictive individuals share impulsivity and executive dysfunction with alcohol\u2010dependent patients","volume":"8","author":"Zhou Z","year":"2014","journal-title":"Front Behav Neurosci"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.drugalcdep.2012.02.020"},{"issue":"356","key":"e_1_2_10_28_1","first-page":"1","article-title":"Aberrant corticostriatal functional circuits in adolescents with Internet addiction disorder","volume":"9","author":"Lin F","year":"2015","journal-title":"Front Hum Neurosci"},{"key":"e_1_2_10_29_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41386\u2010018\u20100019\u20107"},{"key":"e_1_2_10_30_1","doi-asserted-by":"publisher","DOI":"10.1038\/npp.2014.318"},{"key":"e_1_2_10_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsych.2013.11.013"},{"key":"e_1_2_10_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pnpbp.2019.109656"},{"key":"e_1_2_10_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpsychires.2020.12.058"},{"key":"e_1_2_10_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0924-9338(97)83296-8"},{"issue":"20","key":"e_1_2_10_35_1","first-page":"22","article-title":"The Mini\u2010International Neuropsychiatric Interview (MINI): the development and validation of a structured diagnostic psychiatric interview for DSM\u2010IV and ICD\u201010","volume":"59","author":"Sheehan DV","year":"1998","journal-title":"J Clin Psychiatry"},{"key":"e_1_2_10_36_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.psy.43.5.386"},{"key":"e_1_2_10_37_1","doi-asserted-by":"publisher","DOI":"10.1097\/00002508-199706000-00011"},{"issue":"13","key":"e_1_2_10_38_1","first-page":"1","article-title":"DPARSF: a MATLAB toolbox for \u201cpipeline\u201d data analysis of resting\u2010state fMRI","volume":"4","author":"Chao\u2010Gan Y","year":"2010","journal-title":"Front Syst Neurosci"},{"key":"e_1_2_10_39_1","doi-asserted-by":"publisher","DOI":"10.1002\/hbm.1048"},{"issue":"237","key":"e_1_2_10_40_1","first-page":"1","article-title":"Age\u2010related changes in inter\u2010network connectivity by component analysis","volume":"7","author":"Christian L","year":"2015","journal-title":"Front Aging Neurosci"},{"key":"e_1_2_10_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2004.03.027"},{"issue":"2","key":"e_1_2_10_42_1","first-page":"1","article-title":"A baseline for the multivariate comparison of resting\u2010state networks","volume":"5","author":"Allen EA","year":"2011","journal-title":"Front Syst Neurosci"},{"key":"e_1_2_10_43_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nicl.2019.101970"},{"key":"e_1_2_10_44_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.braindev.2006.07.002"},{"key":"e_1_2_10_45_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2003.12.030"},{"key":"e_1_2_10_46_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jneumeth.2008.04.012"},{"key":"e_1_2_10_47_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0905267106"},{"key":"e_1_2_10_48_1","doi-asserted-by":"publisher","DOI":"10.1089\/brain.2014.0253"},{"key":"e_1_2_10_49_1","doi-asserted-by":"publisher","DOI":"10.3109\/10409238.2012.735642"},{"key":"e_1_2_10_50_1","doi-asserted-by":"publisher","DOI":"10.1093\/cercor\/bhp135"},{"issue":"137","key":"e_1_2_10_51_1","first-page":"1","article-title":"A resting state network in the motor control circuit of the basal ganglia","volume":"10","author":"Robinson S","year":"2009","journal-title":"BMC Neurosci"},{"key":"e_1_2_10_52_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.euroneuro.2010.03.008"},{"key":"e_1_2_10_53_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.drugalcdep.2016.12.028"},{"key":"e_1_2_10_54_1","doi-asserted-by":"publisher","DOI":"10.1111\/adb.12101"},{"key":"e_1_2_10_55_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.euroneuro.2016.06.013"},{"key":"e_1_2_10_56_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00429-011-0346-5"},{"issue":"116","key":"e_1_2_10_57_1","first-page":"1","article-title":"Seeking a unified framework for cerebellar function and dysfunction: from circuit operations to cognition","volume":"6","author":"D'Angelo E","year":"2013","journal-title":"Frontiers in Neural Circuits."},{"key":"e_1_2_10_58_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0104102"},{"key":"e_1_2_10_59_1","first-page":"1","article-title":"Disrupted prefrontal regulation of striatum\u2010related craving in Internet gaming disorder revealed by dynamic causal modeling: results from a cue\u2010reactivity task","volume":"2020","author":"Dong G\u2010H","year":"2020","journal-title":"Psychol Med"},{"key":"e_1_2_10_60_1","doi-asserted-by":"publisher","DOI":"10.1038\/nn.2703"},{"key":"e_1_2_10_61_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev\u2010neuro\u2010061010\u2010113641"},{"key":"e_1_2_10_62_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnana.2011.00041"},{"key":"e_1_2_10_63_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.0433-05.2005"},{"key":"e_1_2_10_64_1","doi-asserted-by":"publisher","DOI":"10.1093\/cercor\/bhn041"},{"key":"e_1_2_10_65_1","doi-asserted-by":"publisher","DOI":"10.1556\/2006.2020.00029"},{"key":"e_1_2_10_66_1","first-page":"1","article-title":"Altered effective connectivity from the pregenual anterior cingulate cortex to the laterobasal amygdala mediates the relationship between internet gaming disorder and loneliness","volume":"2020","author":"Wang M","year":"2020","journal-title":"Psychol Med"},{"key":"e_1_2_10_67_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tics.2011.08.003"},{"key":"e_1_2_10_68_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1010654108"},{"key":"e_1_2_10_69_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev\u2010pharmtox\u2010010611\u2010134625"}],"container-title":["Addiction Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/adb.13119","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/adb.13119","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/adb.13119","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,22]],"date-time":"2024-01-22T08:44:25Z","timestamp":1705913065000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/adb.13119"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,12,16]]},"references-count":68,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2022,3]]}},"alternative-id":["10.1111\/adb.13119"],"URL":"https:\/\/doi.org\/10.1111\/adb.13119","archive":["Portico"],"relation":{},"ISSN":["1355-6215","1369-1600"],"issn-type":[{"value":"1355-6215","type":"print"},{"value":"1369-1600","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,12,16]]},"assertion":[{"value":"2020-11-19","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-11-04","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-12-16","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e13119"}}