{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T18:39:08Z","timestamp":1770748748725,"version":"3.50.0"},"reference-count":45,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81971602"],"award-info":[{"award-number":["81971602"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82160327"],"award-info":[{"award-number":["82160327"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82271977"],"award-info":[{"award-number":["82271977"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Addiction Biology"],"published-print":{"date-parts":[[2023,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The temporal variability of the dynamic functional connectivity (dFC) has been suggested as a useful metric for studying abnormal cognitive function. This study aimed to explore the associations between the temporal properties of dFC and memory performance in betel quid dependence (BQD). Sixty\u2010four BQD individuals and 47 gender\u2010 and age\u2010matched healthy controls (HCs) underwent functional magnetic resonance imaging and a series of neuropsychological assessments. The dFC was constructed by calculating the Pearson correlation coefficients within a sliding window and was clustered into three functional connectivity states using k\u2010means clustering. The dFC temporal properties derived from the cluster results were compared between the BQD and HC groups. The results showed that States 1 and 3 featured more frequent and weak connectivity, and State 2 featured less frequent and strong connectivity. There were significant differences for mean dwell time (MDT) in State 3 (<jats:italic>p<\/jats:italic>\u2009=\u20090.022) and fraction of time in State 2 (<jats:italic>p<\/jats:italic>\u2009=\u20090.018) between the BQD and HC groups. Pearson correlation analyses showed that the MDT in State 1 was negatively correlated with long delay free recall and short delay free recall, and the MDT in State 3 was positively correlated with false positive of long delay recall. Our findings provide strong evidence that MDT match the memory performance and suggest new insights into the pathophysiological mechanism of memory disorders in BQD individuals.<\/jats:p>","DOI":"10.1111\/adb.13329","type":"journal-article","created":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T11:02:29Z","timestamp":1693566149000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Dynamic functional connectivity changes associated with decreased memory performance in betel quid dependence"],"prefix":"10.1111","volume":"28","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3294-4351","authenticated-orcid":false,"given":"Yihao","family":"Guo","sequence":"first","affiliation":[{"name":"Department of Radiology Hainan General Hospital (Hainan Affiliated Hospital of Hainan Medical University)  Haikou Hainan China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaoling","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Radiology Hainan General Hospital (Hainan Affiliated Hospital of Hainan Medical University)  Haikou Hainan China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tiansheng","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Radiology Hainan General Hospital (Hainan Affiliated Hospital of Hainan Medical University)  Haikou Hainan China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huijuan","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Radiology Hainan General Hospital (Hainan Affiliated Hospital of Hainan Medical University)  Haikou Hainan China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaoyi","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Radiology Hainan General Hospital (Hainan Affiliated Hospital of Hainan Medical University)  Haikou Hainan China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Weiyuan","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Radiology Hainan General Hospital (Hainan Affiliated Hospital of Hainan Medical University)  Haikou Hainan China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tao","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Geriatric Center Hainan General Hospital (Hainan Affiliated Hospital of Hainan Medical University)  Haikou Hainan China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qingle","family":"Kong","sequence":"additional","affiliation":[{"name":"MR Collaboration Siemens Healthineers Ltd.  Beijing China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Feng","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Radiology Hainan General Hospital (Hainan Affiliated Hospital of Hainan Medical University)  Haikou Hainan China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2023,9]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1080\/13556210120091464"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.drugalcdep.2017.06.039"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1080\/10826084.2018.1432652"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1080\/13556210020091437"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1186\/1747\u2010597X\u20106\u201023"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.drugalcdep.2014.02.022"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.psychres.2018.11.027"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyg.2017.00084"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1177\/0269881118806299"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1470\u20102045(17)30460\u20106"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.4103\/ijdr.IJDR_947_18"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00213\u2010016\u20104331\u20109"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyt.2022.830541"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.25322"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1159\/000453212"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12967\u2010016\u20100784\u20101"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000002638"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00213\u2010018\u20104841\u20108"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyt.2020.00198"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyt.2021.779878"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1002\/hbm.25225"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1002\/hbm.25285"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1002\/hbm.24770"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1093\/cercor\/bhs352"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11682\u2010018\u20109949\u20102"},{"key":"e_1_2_9_27_1","doi-asserted-by":"crossref","unstructured":"YanW ZhangH SuiJ ShenD.Deep Chronnectome Learning via Full Bidirectional Long Short\u2010Term Memory Networks for MCI Diagnosis. Med Image Comput Comput Assist Interv2018; 11072:249\u2013257 doi:10.1007\/978\u20103\u2010030\u201000931\u20101_29.","DOI":"10.1007\/978-3-030-00931-1_29"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nicl.2014.07.003"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnhum.2014.00897"},{"key":"e_1_2_9_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.drugalcdep.2011.07.027"},{"key":"e_1_2_9_31_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1194144"},{"key":"e_1_2_9_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jneumeth.2020.108651"},{"key":"e_1_2_9_33_1","doi-asserted-by":"publisher","DOI":"10.1080\/10826084.2021.1990338"},{"key":"e_1_2_9_34_1","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2022.913241"},{"key":"e_1_2_9_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbr.2022.114121"},{"key":"e_1_2_9_36_1","doi-asserted-by":"publisher","DOI":"10.1002\/hbm.24591"},{"key":"e_1_2_9_37_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awx233"},{"key":"e_1_2_9_38_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000007607"},{"key":"e_1_2_9_39_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467\u2010020\u201017788\u2010z"},{"key":"e_1_2_9_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2019.07.004"},{"key":"e_1_2_9_41_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1523980113"},{"key":"e_1_2_9_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2016.12.061"},{"key":"e_1_2_9_43_1","doi-asserted-by":"publisher","DOI":"10.1093\/cercor\/bhr099"},{"key":"e_1_2_9_44_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.4638\u201014.2015"},{"key":"e_1_2_9_45_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2015.09.010"},{"key":"e_1_2_9_46_1","doi-asserted-by":"publisher","DOI":"10.1109\/RBME.2012.2211076"}],"container-title":["Addiction Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/adb.13329","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,27]],"date-time":"2023-09-27T08:13:32Z","timestamp":1695802412000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/adb.13329"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,9]]},"references-count":45,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2023,10]]}},"alternative-id":["10.1111\/adb.13329"],"URL":"https:\/\/doi.org\/10.1111\/adb.13329","archive":["Portico"],"relation":{},"ISSN":["1355-6215","1369-1600"],"issn-type":[{"value":"1355-6215","type":"print"},{"value":"1369-1600","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,9]]},"assertion":[{"value":"2022-12-13","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-08-15","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-09-01","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e13329"}}