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In China, the most successful intervention for OUD is the community drug rehabilitation where methadone maintenance treatment (MMT) plays a key role. Even though methadone for the treatment of OUD can be helpful, it can cause severe somatic side\u2010effects, which limit its effectivity. Even worse, it can have detrimental effects on cognitive control, which is crucial to regain control over drug intake. Here, we consider the potential use of auricular transcutaneous vagus nerve stimulation (atVNS) as an addition to MMT for opioid withdrawal treatment. Compared to other non\u2010invasive brain stimulation methods, atVNS also targets the locus coeruleus (LC) important for noradrenaline (NA) synthesis. NA is an essential neurotransmitter impacted in opioid withdrawal and also critically involved in cognitive control processes. Its ADD\u2010ON to MMT might be a useful mean to improve mood and enhance cognitive control processes impacted in OUD. We discuss the translational advantages of atVNS in China such as the cultural acceptance of the modality of treatment similar to electroacupuncture. Additionally, the wearability of the ear electrode and at\u2010home self\u2010administration without intense medical supervision makes of atVNS a useful tool to enhance clinical and cognitive outcomes especially in everyday life situation. We discuss how atVNS can be integrated in tele\u2010medical health approaches allowing that innovative treatments can widely be disseminated and continued even in situations of restricted medical access.<\/jats:p>","DOI":"10.1111\/adb.13343","type":"journal-article","created":{"date-parts":[[2023,10,12]],"date-time":"2023-10-12T03:59:43Z","timestamp":1697083183000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Regaining control over opioid use? The potential application of auricular transcutaneous vagus nerve stimulation to improve opioid treatment in China"],"prefix":"10.1111","volume":"28","author":[{"given":"Lorenza","family":"Colzato","sequence":"first","affiliation":[{"name":"Cognitive Psychology, Faculty of Psychology Shandong Normal University  Jinan China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julia","family":"Elmers","sequence":"additional","affiliation":[{"name":"Cognitive Neurophysiology, Department of Child and Adolescent Psychiatry Faculty of Medicine  TU Dresden Germany"},{"name":"Center of Clinical Neuroscience, Department of Neurology University Hospital Carl Gustav Carus  TU Dresden Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaolei","family":"Xu","sequence":"additional","affiliation":[{"name":"Cognitive Psychology, Faculty of Psychology Shandong Normal University  Jinan 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