{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T00:06:28Z","timestamp":1790208388172,"version":"4.1.0"},"reference-count":69,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2024,3,22]],"date-time":"2024-03-22T00:00:00Z","timestamp":1711065600000},"content-version":"vor","delay-in-days":21,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001866","name":"Fonds National de la Recherche Luxembourg","doi-asserted-by":"publisher","award":["C18\/BM\/12552025"],"award-info":[{"award-number":["C18\/BM\/12552025"]}],"id":[{"id":"10.13039\/501100001866","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Addiction Biology"],"published-print":{"date-parts":[[2024,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>\n                    With the advent of digital technologies, online sports betting is spurring a fast\u2010growing expansion. In this study, we examined how sports betting availability modulates the brain connectivity of frequent sports bettors with [problem bettors (PB)] or without [non\u2010problem bettors (NPB)] problematic sports betting. We conducted functional connectivity analyses centred on the ventral anterior insular cortex (vAI), a brain region playing a key role in the dynamic interplay between reward\u2010based processes. We re\u2010analysed a dataset on sports betting availability undertaken in PB (\n                    <jats:italic>n<\/jats:italic>\n                    \u2009=\u200930) and NPB (\n                    <jats:italic>n<\/jats:italic>\n                    \u2009=\u200935). Across all participants, we observed that sports betting availability elicited positive vAI coupling with extended clusters of brain activation (encompassing the putamen, cerebellum, occipital, temporal, precentral and central operculum regions) and negative vAI coupling with the orbitofrontal cortex. Between\u2010group analyses showed increased positive vAI coupling in the PB group, as compared with the NPB group, in the left lateral occipital cortex, extending to the left inferior frontal gyrus, the anterior cingulate gyrus and the right frontal pole. Taken together, these results are in line with the central assumptions of triadic models of addictions, which posit that the insular cortex plays a pivotal role in promoting the drive and motivation to get a reward by \u2018hijacking\u2019 goal\u2010oriented processes toward addiction\u2010related cues. Taken together, these findings showed that vAI functional connectivity is sensitive not only to gambling availability but also to the status of problematic sport betting.\n                  <\/jats:p>","DOI":"10.1111\/adb.13389","type":"journal-article","created":{"date-parts":[[2024,3,22]],"date-time":"2024-03-22T05:59:45Z","timestamp":1711087185000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Increased ventral anterior insular connectivity to sports betting availability indexes problem gambling"],"prefix":"10.1111","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4503-0898","authenticated-orcid":false,"given":"Damien","family":"Brevers","sequence":"first","affiliation":[{"name":"Louvain for Experimental Psychopathology Research Group (LEP), Psychological Sciences Research Institute UCLouvain  Louvain\u2010la\u2010Neuve Belgium"},{"name":"Department of Behavioural and Cognitive Sciences, Institute for Health and Behaviour University of Luxembourg  Esch\u2010sur\u2010Alzette Luxembourg"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9885-3041","authenticated-orcid":false,"given":"Chris","family":"Baeken","sequence":"additional","affiliation":[{"name":"Department of Psychiatry UZ Brussel  Brussels Belgium"},{"name":"Department of Head and Skin, Ghent Experimental Psychiatry (GHEP) Lab Ghent University Hospital, Ghent University  Ghent Belgium"},{"name":"Department of Electrical Engineering Eindhoven University of Technology  Eindhoven The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5127-2549","authenticated-orcid":false,"given":"Antoine","family":"Bechara","sequence":"additional","affiliation":[{"name":"Department of Psychology University of Southern California  California Los Angeles 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