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It is of great practical importance to explore the underlying neural mechanisms behind the behaviour of young smokers. During cue\u2010induced craving, reward system in the brain generates neural oscillations at specific frequencies. The phase\u2013amplitude coupling (PAC) can capture interactions between these frequencies and may be a more sensitive quantitative indicator for characterizing abnormal neural oscillations in smokers. We monitored the electroencephalography (EEG) data of 30 young smokers during a cue task after 12\u2009h of abstinence, dividing the data into the neutral and smoking\u2010related groups based on different experimental stimuli to analyse the relationship between PAC and craving. In addition, we computed the functional connectivity (FC) under the PAC mechanism. The results showed that the young smokers exposed to smoking\u2010related cues under short\u2010term abstinence conditions had significantly lower PAC values and reduced FC strength in the right prefrontal cortex. In contrast, there was a significant increase in PAC values in the parietal cortex and enhanced FC strength. The correlation analysis showed significant correlations between PAC values and craving. These findings demonstrate for the first time that PAC abnormalities in young smokers exposed to smoking\u2010related cues under short\u2010term abstinence conditions may be related to craving and inhibitory control.<\/jats:p>","DOI":"10.1111\/adb.70048","type":"journal-article","created":{"date-parts":[[2025,5,20]],"date-time":"2025-05-20T09:09:34Z","timestamp":1747732174000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["The Phase\u2010Amplitude Coupling Changes Induced by Smoking Cue After 12\u2010H Abstinence in Young Smokers"],"prefix":"10.1111","volume":"30","author":[{"given":"Zhiwei","family":"Ren","sequence":"first","affiliation":[{"name":"School of Digital and Intelligent Industry Inner Mongolia University of Science and Technology  Baotou Inner Mongolia China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juan","family":"Wang","sequence":"additional","affiliation":[{"name":"School of 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