{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T02:51:27Z","timestamp":1777949487772,"version":"3.51.4"},"reference-count":60,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2026,4,14]],"date-time":"2026-04-14T00:00:00Z","timestamp":1776124800000},"content-version":"vor","delay-in-days":13,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81601467"],"award-info":[{"award-number":["81601467"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81871327"],"award-info":[{"award-number":["81871327"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["62106229"],"award-info":[{"award-number":["62106229"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Addiction Biology"],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>This study aims to explore alterations in cortical structure in young individuals with early Internet gaming disorder (IGD) and to provide novel insights for early detection and intervention of disease treatment. We investigated the brain structural magnetic resonance imaging data of 64 individuals with IGD and 47 healthy controls (HCs). The grey matter volume, cortical thickness, and cortical complexity of the two groups were compared separately, and the correlations between the brain regions with structural changes and clinical characteristics in IGD patients were analyzed. Compared to HCs, the IGD group showed no significant GMV differences. However, they exhibited a distinct pattern of right\u2010hemisphere dominant cortical thickening in regions spanning the default mode, dorsal attention, and visual networks (e.g., superior frontal gyrus [SFG], posterior cingulate and lateral occipital gyrus), concurrent with reduced cortical complexity in prefrontal and occipito\u2010parietal areas. Our study suggests that long\u2010term game stimulation is consistent with adaptive resource reallocation. Adolescents with mild IGD demonstrate a unique thickening\u2010complexity decoupling pattern, where cortical thickening in game\u2010related networks coexists with reduced complexity while GMV remains stable. This pattern could reflect a compensatory neuroadaptation phase, highlighting both a critical window for early intervention and specific neural targets for future therapeutic strategies.<\/jats:p>","DOI":"10.1111\/adb.70154","type":"journal-article","created":{"date-parts":[[2026,4,14]],"date-time":"2026-04-14T10:15:58Z","timestamp":1776161758000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Cortical Structure Alterations in Young People With Mild Internet Gaming Disorder"],"prefix":"10.1111","volume":"31","author":[{"given":"Bohui","family":"Mei","sequence":"first","affiliation":[{"name":"Department of Magnetic Resonance Imaging, the First Affiliated Hospital of Zhengzhou University  Zhengzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-7933-9168","authenticated-orcid":false,"given":"Longyao","family":"Ma","sequence":"additional","affiliation":[{"name":"Department of Magnetic Resonance Imaging, the First Affiliated Hospital of Zhengzhou University  Zhengzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qiuying","family":"Tao","sequence":"additional","affiliation":[{"name":"Department of Magnetic Resonance Imaging, the First Affiliated Hospital of Zhengzhou University  Zhengzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jinghan","family":"Dang","sequence":"additional","affiliation":[{"name":"Department of Magnetic Resonance Imaging, the First Affiliated Hospital of Zhengzhou University  Zhengzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jieping","family":"Sun","sequence":"additional","affiliation":[{"name":"Department of Magnetic Resonance Imaging, the First Affiliated Hospital of Zhengzhou University  Zhengzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mengzhe","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Magnetic Resonance Imaging, the First Affiliated Hospital of Zhengzhou University  Zhengzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jingliang","family":"Cheng","sequence":"additional","affiliation":[{"name":"Department of Magnetic Resonance Imaging, the First Affiliated Hospital of Zhengzhou University  Zhengzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4892-6614","authenticated-orcid":false,"given":"Yong","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Magnetic Resonance Imaging, the First Affiliated Hospital of Zhengzhou University  Zhengzhou China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,4,14]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1177\/2167702617723376"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/add.12849"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/dmcn.13754"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1556\/2006.4.2015.010"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph17020448"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.2196\/48439"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.2611-19.2020"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pnpbp.2023.110806"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1556\/2006.8.2019.75"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.dcn.2024.101472"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1186\/1744-9081-9-11"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamapsychiatry.2019.1676"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1503\/jpn.190137"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1006\/nimg.2000.0582"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1006\/nimg.1998.0395"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2010.01.071"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11682-018-9872-6"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1038\/mp.2013.120"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.3550-16.2017"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/cns.14874"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/cns.14582"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2012.09.050"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1556\/2006.7.2018.20"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1556\/2006.2024.00044"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0091506"},{"key":"e_1_2_10_27_1","doi-asserted-by":"publisher","DOI":"10.2463\/mrms.rev.2021-0096"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2014.12.006"},{"key":"e_1_2_10_29_1","doi-asserted-by":"publisher","DOI":"10.4306\/pi.2016.13.1.58"},{"key":"e_1_2_10_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2010.05.075"},{"key":"e_1_2_10_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2004.06.018"},{"key":"e_1_2_10_32_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyg.2013.00863"},{"key":"e_1_2_10_33_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41386-021-01156-6"},{"key":"e_1_2_10_34_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.neuro.29.051605.113009"},{"key":"e_1_2_10_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2018.03.048"},{"key":"e_1_2_10_36_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms23010290"},{"key":"e_1_2_10_37_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnsyn.2021.799274"},{"key":"e_1_2_10_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.conb.2025.103032"},{"key":"e_1_2_10_39_1","doi-asserted-by":"publisher","DOI":"10.2147\/SAR.S484167"},{"key":"e_1_2_10_40_1","doi-asserted-by":"publisher","DOI":"10.1111\/add.70163"},{"key":"e_1_2_10_41_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyt.2020.618319"},{"key":"e_1_2_10_42_1","doi-asserted-by":"publisher","DOI":"10.1196\/annals.1440.011"},{"key":"e_1_2_10_43_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00276-019-02371-z"},{"key":"e_1_2_10_44_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ibneur.2024.11.006"},{"key":"e_1_2_10_45_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chb.2025.108662"},{"key":"e_1_2_10_46_1","doi-asserted-by":"publisher","DOI":"10.3724\/SP.J.1042.2022.02518"},{"issue":"2","key":"e_1_2_10_47_1","first-page":"481","article-title":"The Withdrawal\u2010Related Affective, Gaming Urge, and Anhedonia Symptoms of Internet Gaming Disorder During Abstinence","volume":"11","author":"Yen J. Y.","year":"2022","journal-title":"Journal of Behavioral Addictions"},{"key":"e_1_2_10_48_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00429-021-02223-w"},{"key":"e_1_2_10_49_1","first-page":"433","volume-title":"The Brain's Default Mode Network","author":"Raichle M. E.","year":"2015"},{"key":"e_1_2_10_50_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-neuro-061010-113731"},{"key":"e_1_2_10_51_1","doi-asserted-by":"publisher","DOI":"10.1006\/nimg.2002.1330"},{"key":"e_1_2_10_52_1","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.00006.2019"},{"key":"e_1_2_10_53_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.copsyc.2018.12.023"},{"key":"e_1_2_10_54_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1302581110"},{"key":"e_1_2_10_55_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2014.03.017"},{"key":"e_1_2_10_56_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11682-020-00263-0"},{"key":"e_1_2_10_57_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neubiorev.2017.10.029"},{"key":"e_1_2_10_58_1","doi-asserted-by":"publisher","DOI":"10.1111\/ejn.13987"},{"key":"e_1_2_10_59_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.3302-16.2017"},{"key":"e_1_2_10_60_1","doi-asserted-by":"publisher","DOI":"10.1556\/2006.2021.00049"},{"key":"e_1_2_10_61_1","doi-asserted-by":"publisher","DOI":"10.1002\/hbm.20887"}],"container-title":["Addiction Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/adb.70154","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/adb.70154","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/adb.70154","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T00:14:00Z","timestamp":1777853640000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/adb.70154"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4]]},"references-count":60,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2026,4]]}},"alternative-id":["10.1111\/adb.70154"],"URL":"https:\/\/doi.org\/10.1111\/adb.70154","archive":["Portico"],"relation":{},"ISSN":["1355-6215","1369-1600"],"issn-type":[{"value":"1355-6215","type":"print"},{"value":"1369-1600","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4]]},"assertion":[{"value":"2025-03-24","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-03-26","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-04-14","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70154"}}