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After controlling for other variables, a history of severe CPA<\/jats:styled-content> was a significant independent correlate of an earlier age at first alcohol intoxication compared to both the NA<\/jats:styled-content> (\u03b2\u2009=\u2009\u22120.23, P<\/jats:italic>\u2009<\u20090.01) and MMA<\/jats:styled-content> (\u03b2\u2009=\u20090.20, P<\/jats:italic>\u2009<\u20090.01) groups. Severe CPA<\/jats:styled-content> was also a significant independent correlate of an earlier age at first illicit drug use compared to both the NA<\/jats:styled-content> (\u03b2\u2009=\u2009\u22120.16, P<\/jats:italic>\u2009<\u20090.05) and MMA<\/jats:styled-content> (\u03b2\u2009=\u2009\u22120.15, P<\/jats:italic>\u2009<\u20090.05) groups. In contrast, CPA<\/jats:styled-content> histories were not independently associated with the onset of injecting drug use. After controlling for potential confounders, both the MMA<\/jats:styled-content> (\u03b2\u2009=\u20090.28, P<\/jats:italic>\u2009<\u20090.001) and SA<\/jats:styled-content> (\u03b2\u2009=\u20090.27, P<\/jats:italic>\u2009<\u20090.001) groups were associated with more extensive life\u2010time polydrug use, but did not differ from each other (P<\/jats:italic>\u2009=\u20090.82). After controlling for potential confounders, both MMA<\/jats:styled-content> (\u03b2\u2009=\u20090.20, P<\/jats:italic>\u2009<\u20090.01) and SA<\/jats:styled-content> (\u03b2\u2009=\u20090.33, P<\/jats:italic>\u2009<\u20090.001) group membership were associated with more extensive recent polydrug use but, again, did not differ significantly from each other (P<\/jats:italic>\u2009=\u20090.08).<\/jats:p><\/jats:sec>Conclusions<\/jats:title>Severe childhood physical abuse severity is associated with an earlier initiation into drug use. Any level of abuse is associated with more extensive life\u2010time and recent polydrug use.<\/jats:p><\/jats:sec>","DOI":"10.1111\/add.12428","type":"journal-article","created":{"date-parts":[[2013,11,27]],"date-time":"2013-11-27T08:50:53Z","timestamp":1385542253000},"page":"610-616","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":25,"title":["The association of childhood physical abuse with the onset and extent of drug use among regular injecting drug users"],"prefix":"10.1111","volume":"109","author":[{"given":"Shane","family":"Darke","sequence":"first","affiliation":[{"name":"National Drug and Alcohol Research Centre University of New South Wales Sydney NSW Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michelle","family":"Torok","sequence":"additional","affiliation":[{"name":"National Drug and Alcohol Research Centre University of New South Wales Sydney NSW Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,2,9]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chiabu.2008.09.009"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1521\/suli.2010.40.6.587"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1521\/suli.2006.36.3.336"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1521\/suli.2010.40.1.50"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1360-0443.2001.9622275.x"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.drugalcdep.2013.06.026"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chiabu.2003.09.008"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.2190\/5R62-9PQY-0NEL-TLPA"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.2009.09030310"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.brat.2006.04.007"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1521\/suli.2010.40.4.416"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1360-0443.2012.04001.x"},{"key":"e_1_2_6_14_1","volume-title":"Understanding Addiction as Self\u2010medication. 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