{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T13:00:32Z","timestamp":1788872432869,"version":"build-2803163510"},"reference-count":46,"publisher":"Wiley","issue":"S1","license":[{"start":{"date-parts":[[2014,12,23]],"date-time":"2014-12-23T00:00:00Z","timestamp":1419292800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100004572","name":"National Health and Family Planning Commission of the People's Republic of China","doi-asserted-by":"crossref","award":["131-14-000-105-01"],"award-info":[{"award-number":["131-14-000-105-01"]}],"id":[{"id":"10.13039\/501100004572","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Addiction"],"published-print":{"date-parts":[[2015,1]]},"abstract":"Abstract<\/jats:title>\n \n Aims<\/jats:title>\n \n To describe the data collected by the\n C<\/jats:styled-content>\n hinese methadone maintenance treatment (\n MMT<\/jats:styled-content>\n ) system and the characteristics of clients entering the programme.\n <\/jats:p>\n <\/jats:sec>\n \n Design<\/jats:title>\n \n Descriptive study using routinely collected data from the\n MMT<\/jats:styled-content>\n data management system for the period\n M<\/jats:styled-content>\n arch 2004 and\n M<\/jats:styled-content>\n arch 2010.\n <\/jats:p>\n <\/jats:sec>\n \n Setting<\/jats:title>\n \n All\n MMT<\/jats:styled-content>\n clinics in\n C<\/jats:styled-content>\n hina.\n <\/jats:p>\n <\/jats:sec>\n \n Participants<\/jats:title>\n \n Clients who enrolled for services between\n M<\/jats:styled-content>\n arch 2004 and\n M<\/jats:styled-content>\n arch 2010.\n <\/jats:p>\n <\/jats:sec>\n \n Measurements<\/jats:title>\n \n Routinely collected data included: demographic information; drug use, sexual and criminal behaviours; status of infection with human immunodeficiency virus (\n HIV<\/jats:styled-content>\n ), hepatitis\n C<\/jats:styled-content>\n virus (\n HCV<\/jats:styled-content>\n ) and syphilis; random urine\u2010opiate test results; and the daily methadone dose received. Differences among clients by year were examined.\n <\/jats:p>\n <\/jats:sec>\n \n Findings<\/jats:title>\n \n During the period examined, there were 251\u2009974 clients attending 684 clinics in 27 provinces. Overall, the mean age was 34.4 years, 83.8% were male, 70.2% were unemployed, 75% had ever injected drugs, 17% had shared needles and 7.4% were\n HIV<\/jats:styled-content>\n \u2010positive. The profile of clients changed over time, with fewer\n HIV<\/jats:styled-content>\n \u2010positive individuals, fewer injecting drug users, fewer needle\u2010sharers, fewer females and fewer unemployed. Half the clients dropped out within 6 months. The average final dose received was 49.4\u2009mg. The estimated probability of interrupting treatment before 6 months was 52.5%.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n \n The profile of clients enrolling in methadone maintenance treatment in\n C<\/jats:styled-content>\n hina is continually changing and appears to be associated with reduced risk of\n HIV<\/jats:styled-content>\n . High dropout in the programme may limit its effectiveness. The availability of a centralized, real\u2010time data system was extremely useful for monitoring the progress of the\n C<\/jats:styled-content>\n hinese methadone maintenance treatment programme.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/add.12781","type":"journal-article","created":{"date-parts":[[2014,12,24]],"date-time":"2014-12-24T08:18:48Z","timestamp":1419409128000},"page":"29-39","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":27,"title":["Who uses methadone services in\n C<\/scp>\n hina? Monitoring the world's largest methadone programme"],"prefix":"10.1111","volume":"110","author":[{"given":"Sheena G.","family":"Sullivan","sequence":"first","affiliation":[{"name":"National Center for AIDS\/STD Control and Prevention Chinese Center for Disease Control and Prevention Beijing China"},{"name":"Department of Epidemiology University of California Los Angeles CA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zunyou","family":"Wu","sequence":"additional","affiliation":[{"name":"National Center for AIDS\/STD Control and Prevention Chinese Center for Disease Control and Prevention Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keming","family":"Rou","sequence":"additional","affiliation":[{"name":"National Center for AIDS\/STD Control and Prevention Chinese Center for Disease Control and Prevention Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lin","family":"Pang","sequence":"additional","affiliation":[{"name":"National Center for AIDS\/STD Control and Prevention Chinese Center for Disease Control and Prevention Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Luo","sequence":"additional","affiliation":[{"name":"National Center for AIDS\/STD Control and Prevention Chinese Center for Disease Control and Prevention Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Changhe","family":"Wang","sequence":"additional","affiliation":[{"name":"National Center for AIDS\/STD Control and Prevention Chinese Center for Disease Control and Prevention Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaobin","family":"Cao","sequence":"additional","affiliation":[{"name":"National Center for AIDS\/STD Control and Prevention Chinese Center for Disease Control and Prevention Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenyuan","family":"Yin","sequence":"additional","affiliation":[{"name":"National Center for AIDS\/STD Control and Prevention Chinese Center for Disease Control and Prevention Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Enwu","family":"Liu","sequence":"additional","affiliation":[{"name":"National Center for AIDS\/STD Control and Prevention Chinese Center for Disease Control and Prevention Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guodong","family":"Mi","sequence":"additional","affiliation":[{"name":"National Center for AIDS\/STD Control and Prevention Chinese Center for Disease Control and Prevention Beijing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"National Methadone Maintenance Treatment Working Group","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2014,12,23]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.aids.0000304704.71917.64"},{"key":"e_1_2_6_3_1","unstructured":"WuZ.2004Landmark government methadone maintenance program in mainland China Paper presented at the 15th International AIDS Conference Bangkok 11\u201316 July."},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/dyq210"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.drugpo.2006.11.014"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.drugpo.2009.09.002"},{"key":"e_1_2_6_7_1","unstructured":"Ministry of Health Ministry of Public Security China Food and Drug Administration.Implementation Protocol of the Community\u2010Based Methadone Maintenance Treatment Program for Opiate Addicts in China. 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