{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,13]],"date-time":"2026-06-13T12:38:37Z","timestamp":1781354317403,"version":"3.54.1"},"reference-count":11,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2015,3,15]],"date-time":"2015-03-15T00:00:00Z","timestamp":1426377600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2015,3,15]],"date-time":"2015-03-15T00:00:00Z","timestamp":1426377600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"name":"Australian National Health and Medical Research Council (NHMRC)","award":["1005668"],"award-info":[{"award-number":["1005668"]}]},{"name":"L.D.","award":["1041742"],"award-info":[{"award-number":["1041742"]}]},{"name":"S.L.","award":["1035149"],"award-info":[{"award-number":["1035149"]}]},{"name":"B.L.","award":["1073858"],"award-info":[{"award-number":["1073858"]}]},{"name":"R.P.M.","award":["1045318"],"award-info":[{"award-number":["1045318"]}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Addiction"],"published-print":{"date-parts":[[2015,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background and Aims<\/jats:title>\n                    <jats:p>To examine characteristics of first\u2010time methadone and buprenorphine clients and factors associated with risk of leaving first treatment in New South Wales (NSW), Australia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>Retrospective linkage study of opioid substitution therapy (OST) treatment, court, custody and mortality data.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting<\/jats:title>\n                    <jats:p>NSW, Australia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Participants<\/jats:title>\n                    <jats:p>First\u2010time OST entrants (August 2001\u2013December 2010).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Measurements<\/jats:title>\n                    <jats:p>Characteristics of clients were examined. Time\u2010dependent Cox models examined factors associated with the risk of leaving first treatment, with demographic, criminographic and treatment variables jointly considered. Interactions between medication and other variables upon risk of leaving treatment were examined.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Findings<\/jats:title>\n                    <jats:p>There were 15\u2009600 treatment entrants: 7183 (46%) commenced buprenorphine, 8417 (54%) commenced methadone; the proportion entering buprenorphine increased over time. Those starting buprenorphine switched medications more frequently and had more subsequent treatment episodes. Buprenorphine retention was also poorer. On average, 44% spent 3+ months in treatment compared with 70% of those commencing methadone; however, buprenorphine retention for first\u2010time entrants improved over time, whereas methadone retention did not. Multivariable Cox models indicated that in addition to sex, age, treatment setting and criminographic variables, the risk of leaving a first treatment episode was greater on any given day for those receiving buprenorphine, and was dependent on the year treatment was initiated. There was no interaction between any demographic variables and medication received, suggesting no clear evidence of any particular groups for whom each medication might be better suited in terms of improving retention.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Although retention rates for buprenorphine treatment have improved in New South Wales, Australia, individuals starting methadone treatment still show higher retention rates.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/add.12834","type":"journal-article","created":{"date-parts":[[2014,12,16]],"date-time":"2014-12-16T15:38:55Z","timestamp":1418744335000},"page":"646-655","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":64,"title":["A longitudinal comparison of retention in buprenorphine and methadone treatment for opioid dependence in New South Wales, Australia"],"prefix":"10.1111","volume":"110","author":[{"given":"Lucy","family":"Burns","sequence":"first","affiliation":[{"name":"National Drug and Alcohol Research Centre University of NSW  Sydney Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natasa","family":"Gisev","sequence":"additional","affiliation":[{"name":"National Drug and Alcohol Research Centre University of NSW  Sydney Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah","family":"Larney","sequence":"additional","affiliation":[{"name":"National Drug and Alcohol Research Centre University of NSW  Sydney Australia"},{"name":"Alpert Medical School Brown University  Providence Rhode Island USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timothy","family":"Dobbins","sequence":"additional","affiliation":[{"name":"National Centre for Epidemiology and Population Health Australian National University  Canberra Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amy","family":"Gibson","sequence":"additional","affiliation":[{"name":"Centre for Health Research University of Western Sydney  Sydney Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jo","family":"Kimber","sequence":"additional","affiliation":[{"name":"National Drug and Alcohol Research Centre University of NSW  Sydney Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Briony","family":"Larance","sequence":"additional","affiliation":[{"name":"National Drug and Alcohol Research Centre University of NSW  Sydney Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard P.","family":"Mattick","sequence":"additional","affiliation":[{"name":"National Drug and Alcohol Research Centre University of NSW  Sydney Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tony","family":"Butler","sequence":"additional","affiliation":[{"name":"Kirby Institute University of NSW  Sydney Australia"},{"name":"Australia School of Public Health and Community Medicine University of NSW  Sydney Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8513-2218","authenticated-orcid":false,"given":"Louisa","family":"Degenhardt","sequence":"additional","affiliation":[{"name":"National Drug and Alcohol Research Centre University of NSW  Sydney Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,3,15]]},"reference":[{"key":"e_1_2_6_2_1","volume-title":"Methadone Maintenance Treatment and Other Opioid Replacement Pharmacotherapies","author":"Ward J.","year":"1998"},{"key":"e_1_2_6_3_1","first-page":"1","article-title":"Methadone maintenance therapy versus no opioid replacement therapy for opioid dependence","volume":"2","author":"Mattick R. 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NSW Bureau of Crime Statistics and Research","author":"Goh D.","year":"2014"},{"key":"e_1_2_6_12_1","volume-title":"Drug and Alcohol Office Research Report","author":"Drug and Alcohol Office","year":"2014"}],"container-title":["Addiction"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fadd.12834","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fadd.12834","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/add.12834","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/add.12834","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/add.12834","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,9]],"date-time":"2026-06-09T03:03:36Z","timestamp":1780974216000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/add.12834"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,3,15]]},"references-count":11,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2015,4]]}},"alternative-id":["10.1111\/add.12834"],"URL":"https:\/\/doi.org\/10.1111\/add.12834","archive":["Portico"],"relation":{},"ISSN":["0965-2140","1360-0443"],"issn-type":[{"value":"0965-2140","type":"print"},{"value":"1360-0443","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,3,15]]},"assertion":[{"value":"2014-03-31","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2014-12-08","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2015-03-15","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}