{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T20:35:38Z","timestamp":1787171738645,"version":"build-2736575974"},"reference-count":71,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2015,11,19]],"date-time":"2015-11-19T00:00:00Z","timestamp":1447891200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Addiction"],"published-print":{"date-parts":[[2016,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>\n                      Aim\n                      <jats:styled-content>s<\/jats:styled-content>\n                    <\/jats:title>\n                    <jats:p>To identify promising intervention components intended to help smokers to attain and maintain abstinence in their quit smoking attempts.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>A fully crossed, six\u2010factor randomized fractional factorial experiment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting<\/jats:title>\n                    <jats:p>Eleven primary care clinics in southern Wisconsin, USA.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Participants<\/jats:title>\n                    <jats:p>A total of 637 adult smokers (55% women, 88% white) motivated to quit smoking who visited primary care clinics.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Interventions<\/jats:title>\n                    <jats:p>Six intervention components designed to prepare smokers to quit, and achieve and maintain abstinence (i.e. for the preparation, cessation and maintenance phases of smoking treatment): (1) preparation nicotine patch versus none; (2) preparation nicotine gum versus none; (3) preparation counseling versus none; (4) intensive cessation in\u2010person counseling versus minimal; (5) intensive cessation telephone counseling versus minimal; and (6) 16 versus 8\u2009weeks of combination nicotine replacement therapy (nicotine patch \u2009+\u2009 nicotine gum).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Measurements<\/jats:title>\n                    <jats:p>Seven\u2010day self\u2010reported point\u2010prevalence abstinence at 16\u2009weeks.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Findings<\/jats:title>\n                    <jats:p>\n                      Preparation counseling significantly improved week 16 abstinence rates (\n                      <jats:italic>P<\/jats:italic>\n                      = .04), while both forms of preparation nicotine replacement therapy interacted synergistically with intensive cessation in\u2010person counseling (\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u20090.05). Conversely, intensive cessation phone counseling and intensive cessation in\u2010person counseling interacted antagonistically (\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u20090.05)\u2014these components produced higher abstinence rates by themselves than in combination.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Preparation counseling and the combination of intensive cessation in\u2010person counseling with preparation nicotine gum or patch are promising intervention components for smoking and should be evaluated as an integrated treatment package.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/add.13162","type":"journal-article","created":{"date-parts":[[2015,11,19]],"date-time":"2015-11-19T01:47:05Z","timestamp":1447897625000},"page":"129-141","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":82,"title":["Identifying effective intervention components for smoking cessation: a factorial screening experiment"],"prefix":"10.1111","volume":"111","author":[{"given":"Megan E.","family":"Piper","sequence":"first","affiliation":[{"name":"Center for Tobacco Research and Intervention University of Wisconsin School of Medicine and Public Health  Madison WI USA"},{"name":"University of Wisconsin School of Medicine and Public Health Department of Medicine  Madison WI USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael C.","family":"Fiore","sequence":"additional","affiliation":[{"name":"Center for Tobacco Research and Intervention University of Wisconsin School of Medicine and Public Health  Madison WI USA"},{"name":"University of Wisconsin School of Medicine and Public Health Department of Medicine  Madison WI USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stevens S.","family":"Smith","sequence":"additional","affiliation":[{"name":"Center for Tobacco Research and Intervention University of Wisconsin School of Medicine and Public Health  Madison WI USA"},{"name":"University of Wisconsin School of Medicine and Public Health Department of Medicine  Madison WI USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Fraser","sequence":"additional","affiliation":[{"name":"Center for Tobacco Research and Intervention University of Wisconsin School of Medicine and Public Health  Madison WI USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel M.","family":"Bolt","sequence":"additional","affiliation":[{"name":"University of Wisconsin Department of Educational Psychology  Madison WI USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linda M.","family":"Collins","sequence":"additional","affiliation":[{"name":"The Methodology Center The Pennsylvania State University  University Park PA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robin","family":"Mermelstein","sequence":"additional","affiliation":[{"name":"University of Illinois at Chicago Institute for Health Research and Policy  Chicago IL USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tanya R.","family":"Schlam","sequence":"additional","affiliation":[{"name":"Center for Tobacco Research and Intervention University of Wisconsin School of Medicine and Public Health  Madison WI USA"},{"name":"University of Wisconsin School of Medicine and Public Health Department of Medicine  Madison WI USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jessica W.","family":"Cook","sequence":"additional","affiliation":[{"name":"Center for Tobacco Research and Intervention University of Wisconsin School of Medicine and Public Health  Madison WI USA"},{"name":"University of Wisconsin School of Medicine and Public Health Department of Medicine  Madison WI USA"},{"name":"William S. Middleton Memorial Veterans Hospital  Madison WI USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Douglas E.","family":"Jorenby","sequence":"additional","affiliation":[{"name":"Center for Tobacco Research and Intervention University of Wisconsin School of Medicine and Public Health  Madison WI USA"},{"name":"University of Wisconsin School of Medicine and Public Health Department of Medicine  Madison WI USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei\u2010Yin","family":"Loh","sequence":"additional","affiliation":[{"name":"University of Wisconsin Department of Statistics  Madison WI USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timothy B.","family":"Baker","sequence":"additional","affiliation":[{"name":"Center for Tobacco Research and Intervention University of Wisconsin School of Medicine and Public Health  Madison WI USA"},{"name":"University of Wisconsin School of Medicine and Public Health Department of Medicine  Madison WI USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,11,19]]},"reference":[{"key":"e_1_2_8_2_1","volume-title":"The Health Consequences Of Smoking\u201450 Years of Progress: A Report of the Surgeon General","author":"US Department of Health and Human Services (USDHHS)","year":"2014"},{"key":"e_1_2_8_3_1","volume-title":"Treating Tobacco Use and Dependence: 2008 Update","author":"Fiore M. 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