{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T04:55:08Z","timestamp":1785819308078,"version":"3.56.0"},"reference-count":31,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2017,4,7]],"date-time":"2017-04-07T00:00:00Z","timestamp":1491523200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2017,4,7]],"date-time":"2017-04-07T00:00:00Z","timestamp":1491523200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Addiction"],"published-print":{"date-parts":[[2017,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>To study the effectiveness of a brief intervention (BI) associated with the ASSIST (Alcohol Smoking and Substance Involvement Screening Test) for alcohol and illicit drug use as part of a systematic screening program implemented in primary care.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>A multi\u2010center randomized open\u2010label trial stratified using the ASSIST\u2010specific substance involvement score (for alcohol, scores ranged from 11 to 15 and 16 to 20; and for the other substances from 4 to 12 and 13 to 20).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting<\/jats:title>\n                    <jats:p>\n                      A total of 19 primary care centers (\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u00a0520), eight emergency rooms (\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u00a0195) and five police stations (\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u00a091) were evaluated.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Participants<\/jats:title>\n                    <jats:p>A total of 12\u00a0217 people aged between 19 and 55\u00a0years were screened for moderate alcohol and drug use risk as defined by the ASSIST Chilean version. A total of 806 non\u2010treatment\u2010seekers were randomized.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Intervention and comparison<\/jats:title>\n                    <jats:p>\n                      ASSIST\u2010linked BI (\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u00a0400) compared with an informational pamphlet on risk associated with substance use (\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u00a0406).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Measurements<\/jats:title>\n                    <jats:p>Total ASSIST alcohol and illicit involvement score (ASSIST\u2013AI), and ASSIST\u2010specific score for alcohol, cannabis and cocaine at baseline and at 3\u2010month follow\u2010up.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Findings<\/jats:title>\n                    <jats:p>Sixty\u2010two per cent of participants completed follow\u2010up. An intention\u2010to\u2010treat analysis showed no difference between the two groups for the ASSIST\u2013AI score [mean difference (MD)\u00a0=\u00a0\u2212\u00a00.17, confidence interval (CI)\u00a0=\u00a0\u22121.87, 2.20], either for specific scores alcohol (MD\u00a0=\u00a00.18, CI\u00a0=\u00a0\u22121.45, 1.10), cannabis (MD\u00a0=\u00a0\u20130.62, CI\u00a0=\u00a0\u22120.89, 2.14) or cocaine (MD\u00a0=\u00a0\u20130.79, CI\u00a0=\u00a0\u22122.89, 4.47).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>It is not clear whether a brief intervention associated with the Alcohol Smoking and Substance Involvement Screening Test is more effective than an informational pamphlet in reducing alcohol and illicit substance consumption in non\u2010treatment\u2010seeking, primary care users with moderate risk.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/add.13808","type":"journal-article","created":{"date-parts":[[2017,2,27]],"date-time":"2017-02-27T00:32:52Z","timestamp":1488155572000},"page":"1462-1469","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":26,"title":["A randomized controlled trial of a brief intervention for alcohol and drugs linked to the Alcohol, Smoking and Substance Involvement Screening Test (ASSIST) in primary health care in Chile"],"prefix":"10.1111","volume":"112","author":[{"given":"Fernando","family":"Poblete","sequence":"first","affiliation":[{"name":"School of Medicine, Department of Public Health Pontificia Universidad Cat\u00f3lica de Chile  Santiago Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicolas A.","family":"Barticevic","sequence":"additional","affiliation":[{"name":"School of Medicine, Department of Family Medicine Pontificia Universidad Cat\u00f3lica de Chile  Santiago Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Soledad","family":"Zuzulich","sequence":"additional","affiliation":[{"name":"School of Medicine, Nursing School Pontificia Universidad Cat\u00f3lica de Chile  Santiago Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rodrigo","family":"Portilla","sequence":"additional","affiliation":[{"name":"Research Department National Service for Prevention and Rehabilitation of Drug and Alcohol Consumption  Santiago Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alvaro","family":"Castillo\u2010Carniglia","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, UC Davis School of Medicine Violence Prevention Research Program  Sacramento CA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jaime C.","family":"Sapag","sequence":"additional","affiliation":[{"name":"School of Medicine, Department of Family Medicine Pontificia Universidad Cat\u00f3lica de Chile  Santiago Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luis","family":"Villarroel","sequence":"additional","affiliation":[{"name":"School of Medicine, Department of Public Health Pontificia Universidad Cat\u00f3lica de Chile  Santiago Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brena F.","family":"Sena","sequence":"additional","affiliation":[{"name":"Columbia University School of Public Health  New York NY USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Magdalena","family":"Galarce","sequence":"additional","affiliation":[{"name":"School of Medicine, Center for Study of Addiction Pontificia Universidad Catolica de Chile  Santiago Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,4,7]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1300\/J465v28n03_03"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amepre.2007.09.035"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.drugalcdep.2008.08.003"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1360-0443.2002.00185.x"},{"key":"e_1_2_6_6_1","unstructured":"World Health Organization Working Group.Intervenci\u00f3n breve vinculada a ASSIST para el consumo problem\u00e1tico de sustancias \u2010 Manual para uso en la atenci\u00f3n primaria [The ASSIST\u2010linked brief intervention for hazardous and harmful substance use: a manual for use in primary care].2010; [internet]. 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