{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,9]],"date-time":"2026-06-09T05:59:17Z","timestamp":1780984757129,"version":"3.54.1"},"reference-count":47,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2017,5,22]],"date-time":"2017-05-22T00:00:00Z","timestamp":1495411200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2017,5,22]],"date-time":"2017-05-22T00:00:00Z","timestamp":1495411200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"name":"The Centre for ADR monitoring of Guangdong","award":["GZSW11175FT4055"],"award-info":[{"award-number":["GZSW11175FT4055"]}]},{"name":"Centre for ADR monitoring of Guangdong","award":["GZSW11175FT4055"],"award-info":[{"award-number":["GZSW11175FT4055"]}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Addiction"],"published-print":{"date-parts":[[2017,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>To test, among Chinese adolescents: (1) whether childhood maltreatment is associated with non\u2010medical use of prescription drugs (NMUPD) and (2) whether there are interaction effects of childhood maltreatment and depressive symptoms on NMUPD.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>A secondary analysis of the cross\u2010sectional data collected from 7th\u2010 and 12th\u2010graders who were sampled using a multi\u2010stage, stratified\u2010cluster, random\u2010sampling method in the 2015 School\u2010based Chinese Adolescents Health Survey (SCAHS).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting<\/jats:title>\n                    <jats:p>Surveys conducted in high schools in six cities of China in 2015.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Participants<\/jats:title>\n                    <jats:p>There were 24\u2009457 students who were invited to participate and 23\u2009039 students\u2019 questionnaires were completed and qualified for our survey.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Measurements<\/jats:title>\n                    <jats:p>The outcomes comprised self\u2010report of NMUPD (prior 30\u00a0days); a history of childhood maltreatment was our main predictor. Other covariates included depressive symptoms, smoking, drinking and demographics. Data were analysed using multi\u2010level regression modelling.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Findings<\/jats:title>\n                    <jats:p>Our final multivariable logistic regression models demonstrated that after adjusting for other variables, physical abuse was associated positively with non\u2010medical use of opioids [adjusted odds ratio (AOR)\u00a0=\u00a01.13, 95% confidence interval (CI)\u00a0=\u00a01.10\u20131.22], sedatives (AOR\u00a0=\u00a01.11, 95% CI\u00a0=\u00a01.10\u20131.21) and any prescription drugs (AOR\u00a0=\u00a01.13, 95% CI\u00a0=\u00a01.09\u20131.20); emotional abuse, sexual abuse and emotional neglect were also associated with an increased risk of opioids, sedatives and any prescription drugs misuse; students who reported that they had experienced childhood physical neglect were more likely to be involved in the non\u2010medical use of sedatives (AOR\u00a0=\u00a01.08, 95% CI\u00a0=\u00a01.04\u20131.12) and any prescription drugs (AOR\u00a0=\u00a01.06, 95% CI\u00a0=\u00a01.03\u20131.10). Additionally, there was no evidence of interaction effects on NMUPD between depressive symptoms and each of physical abuse, emotional abuse, sexual abuse, physical neglect and emotional neglect, respectively.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Maltreatment while a child is associated with an increased risk of non\u2010medical use of prescription drugs (NMUPD) among Chinese adolescents. The interactions of maltreatment while a child and depressive symptoms do not appear to be associated significantly with NMUPD among Chinese adolescents.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/add.13850","type":"journal-article","created":{"date-parts":[[2017,4,21]],"date-time":"2017-04-21T09:11:38Z","timestamp":1492765898000},"page":"1600-1609","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":24,"title":["Associations between childhood maltreatment and non\u2010medical use of prescription drugs among Chinese adolescents"],"prefix":"10.1111","volume":"112","author":[{"given":"Lan","family":"Guo","sequence":"first","affiliation":[{"name":"Department of Medical statistics and Epidemiology, School of Public Health Sun Yat\u2010sen University  Guangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Medical statistics and Epidemiology, School of Public Health Sun Yat\u2010sen University  Guangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianxiong","family":"Deng","sequence":"additional","affiliation":[{"name":"Center for ADR monitoring of Guangdong  Guangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xue","family":"Gao","sequence":"additional","affiliation":[{"name":"Center for ADR monitoring of Guangdong  Guangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guoliang","family":"Huang","sequence":"additional","affiliation":[{"name":"Center for ADR monitoring of Guangdong  Guangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinghui","family":"Huang","sequence":"additional","affiliation":[{"name":"Center for ADR monitoring of Guangdong  Guangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xueqing","family":"Deng","sequence":"additional","affiliation":[{"name":"Department of Medical statistics and Epidemiology, School of Public Health Sun Yat\u2010sen University  Guangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei\u2010Hong","family":"Zhang","sequence":"additional","affiliation":[{"name":"Epidemiology, Biostatistics and Clinical Research Centre, School of Public Health Universit\u00e9 Libre de Bruxelles (ULB)  Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ciyong","family":"Lu","sequence":"additional","affiliation":[{"name":"Department of Medical statistics and Epidemiology, School of Public Health Sun Yat\u2010sen University  Guangzhou China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2017,5,22]]},"reference":[{"key":"e_1_2_9_2_1","volume-title":"Report of the Consultation on Child Abuse Prevention","author":"World Health Organization","year":"1999"},{"key":"e_1_2_9_3_1","volume-title":"Preventing Child Maltreatment: a Guide to Taking Action and Generating Evidence","author":"World Health Organization","year":"2006"},{"key":"e_1_2_9_4_1","first-page":"353","article-title":"Child maltreatment in the worldwide: a review article","volume":"3","author":"Abbasi M. 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