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Instead, increases in conduct problems predicted increases in cannabis use and ultimately CUD, with some of the effect mediated by increases in the prevalence of peer cannabis use [\u03b2\u00a0=\u00a00.12, 95% confidence interval (CI)\u00a0=\u00a00.07, 0.20]. Additionally, affiliation with peers who used cannabis predicted subsequent CUD via increased personal cannabis use (\u03b2\u00a0=\u00a00.08, 95% CI\u00a0=\u00a00.04, 0.14). Significant within\u2010person betas for the cross\u2010lagged effects ranged between 0.20 and 0.27.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Cannabis use in adolescence does not appear to lead to greater conduct problems or association with cannabis\u2010using peers apart from pre\u2010existing conduct problems. Instead, adolescents who (1) increasingly affiliate with cannabis\u2010using peers or (2) have increasing levels of conduct problems are more likely to use cannabis, and this cascading chain of events appears to predict cannabis use disorder in emerging adulthood.<\/jats:p><\/jats:sec>","DOI":"10.1111\/add.14456","type":"journal-article","created":{"date-parts":[[2018,11,20]],"date-time":"2018-11-20T12:00:26Z","timestamp":1542715226000},"page":"485-493","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":39,"title":["Disentangling longitudinal relations between youth cannabis use, peer cannabis use, and conduct problems: developmental cascading links to cannabis use disorder"],"prefix":"10.1111","volume":"114","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0072-1276","authenticated-orcid":false,"given":"Ivy N.","family":"Defoe","sequence":"first","affiliation":[{"name":"Annenberg Public Policy Center The University of Pennsylvania  Philadelphia PA USA"},{"name":"Psychology of Conflict, Risk and Safety, University of Twente  Enschede the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Atika","family":"Khurana","sequence":"additional","affiliation":[{"name":"College of Education University of Oregon  Eugene OR USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura M.","family":"Betancourt","sequence":"additional","affiliation":[{"name":"The Children's Hospital of Philadelphia Division of Neonatology  Philadelphia PA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hallam","family":"Hurt","sequence":"additional","affiliation":[{"name":"The Children's Hospital of Philadelphia Division of Neonatology  Philadelphia PA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Romer","sequence":"additional","affiliation":[{"name":"Annenberg Public Policy Center The University of Pennsylvania  Philadelphia PA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,11,20]]},"reference":[{"key":"e_1_2_8_2_1","unstructured":"RolleI. 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