{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T21:50:22Z","timestamp":1791669022121,"version":"4.3.4"},"reference-count":34,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2019,12,11]],"date-time":"2019-12-11T00:00:00Z","timestamp":1576022400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Addiction"],"published-print":{"date-parts":[[2020,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background and aims<\/jats:title><jats:p>Fetal alcohol spectrum disorder (FASD) is a preventable condition that imposes a significant financial burden on societies. Funding of FASD prevention is a small portion of the total expenditures associated with FASD. This paper aimed to review the literature on the costs of and savings from prevention of FASD and present a model for the United States and Canada of projected savings based on expansion of existing evidence\u2010based prevention models.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A systematic review of published literature on the cost of FASD prevention was conducted and experts in the field were interviewed. Studies that reported the cost of primary prevention of FASD were eligible for further consideration.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Applying evidenced\u2010based prevention programs to women at highest risk to have a future child with FASD greatly reduces the cost of prevention. In the United States, one case of FASD can be prevented for as little as USD $20 200 \u2013 47 615. Cost of prevention is considerably less expensive than cost of care for a case of FASD.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Expansion of risk\u2010based prevention strategies for fetal alcohol spectrum disorder in the United States and Canada would be an economically efficient and worthwhile investment for society.<\/jats:p><\/jats:sec>","DOI":"10.1111\/add.14841","type":"journal-article","created":{"date-parts":[[2019,10,19]],"date-time":"2019-10-19T11:08:18Z","timestamp":1571483298000},"page":"409-417","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":37,"title":["Fetal alcohol spectrum disorder: a systematic review of the cost of and savings from prevention in the United States and Canada"],"prefix":"10.1111","volume":"115","author":[{"given":"Jacob R.","family":"Greenmyer","sequence":"first","affiliation":[{"name":"Department of Pediatrics University of North Dakota School of Medicine and Health Sciences  Grand Forks ND USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Svetlana","family":"Popova","sequence":"additional","affiliation":[{"name":"Institute for Mental Health Policy Research, Centre for Addiction and Mental Health, Dalla Lana School of Public Health University of Toronto  Toronto Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marilyn G.","family":"Klug","sequence":"additional","affiliation":[{"name":"Department of Population Health University of North Dakota School of Medicine and Health Sciences  Grand forks ND USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7199-2711","authenticated-orcid":false,"given":"Larry","family":"Burd","sequence":"additional","affiliation":[{"name":"Department of Pediatrics University of North Dakota School of Medicine and Health Sciences  Grand Forks ND USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,12,11]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/ADM.0000000000000438"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/alcalc\/agr029"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ntt.2010.10.008"},{"key":"e_1_2_8_5_1","volume-title":"Fetal alcohol syndrome\u2014diagnosis, epidemiology, prevention, and treatment","author":"Stratton K. 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