{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T00:34:45Z","timestamp":1747182885764,"version":"3.40.5"},"reference-count":22,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2020,7,18]],"date-time":"2020-07-18T00:00:00Z","timestamp":1595030400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Addiction"],"published-print":{"date-parts":[[2021,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aims<\/jats:title><jats:p>To compare success rates and characteristics of smokers treated a second time by a smokers\u2019 clinic with success rates of their first treatment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>Retrospective cohort study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>Tobacco Dependence Treatment clinic in Prague, Czech Republic, between 2005 and 2017.<\/jats:p><\/jats:sec><jats:sec><jats:title>Participants<\/jats:title><jats:p>A total of 5225 smokers treated either once (<jats:italic>n<\/jats:italic>\u00a0=\u00a05006, single treatment sample, SS) or also second time (<jats:italic>n<\/jats:italic>\u00a0=\u00a0219, re\u2010treated sample, RS), on average 4.47\u00a0years after the first visit.<\/jats:p><\/jats:sec><jats:sec><jats:title>Intervention<\/jats:title><jats:p>Smokers received intensive treatment of tobacco dependence with pharmacotherapy options. Outcomes were evaluated after 1\u00a0year. In case of failure or relapse, participants could undergo re\u2010treatment in the same setting at least 1\u00a0year after the start of the first treatment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Measurements<\/jats:title><jats:p>Twelve\u2010month self\u2010reported continuous abstinence; CO\u2010validated (\u2264\u00a06\u00a0parts per million); number of visits; type of pharmacotherapy; mental health history; Fagerstr\u00f6m Test for Cigarette Dependence; time between first and second treatment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The abstinence rate in the SS was 34.8% [95% confidence interval (CI)\u00a0=\u00a033.4%, 36.1%] and in the RS was 37% (95% CI\u00a0=\u00a030.6%, 43.8%) and 39.7% (95% CI\u00a0=\u00a033.2%, 45.5%) for their first and second treatments, respectively. The samples were comparable on smoking and socio\u2010demographic characteristics and pharmacotherapy used, but the RS in the second treatment had a higher prevalence of diagnosed mental health disorder at 39.3% (95% CI\u00a0=\u00a032.8%; 46.1%) compared with 23.7% (95% CI\u00a0=\u00a022.5%; 24.9%) in the SS. Participants who initiated their second quit attempt 1 to 2\u00a0years after the first one were less successful than those who initiated their second quit attempt later (25 versus 43%; <jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.05). The results of the first treatment cycle were not found to be a reliable predictor for outcomes of the second cycle of treatment in univariate or multivariate logistic regression (odds ratio\u00a0=\u00a01.35, 95% CI\u00a0=\u00a00.70\u20132.63, <jats:italic>P<\/jats:italic>\u00a0=\u00a00.373).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>In Prague, Czech Republic, smokers re\u2010attending stop\u2010smoking treatment more than 2\u00a0years after their previous quit attempt appear to achieve similar success rates to those being treated for the first time.<\/jats:p><\/jats:sec>","DOI":"10.1111\/add.15175","type":"journal-article","created":{"date-parts":[[2020,6,27]],"date-time":"2020-06-27T10:24:56Z","timestamp":1593253496000},"page":"346-355","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Comparison between success rates for smokers re\u2010treated by a smokers\u2019 clinic and success rates for smokers treated for the first time"],"prefix":"10.1111","volume":"116","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4085-2390","authenticated-orcid":false,"given":"Lenka","family":"Stepankova","sequence":"first","affiliation":[{"name":"Centre for Tobacco Dependence, 3rd Medical Department, Department of Endocrinology and Metabolism, First Faculty of Medicine Charles University in Prague and General University Hospital in Prague  Czech Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0190-926X","authenticated-orcid":false,"given":"Eva","family":"Kralikova","sequence":"additional","affiliation":[{"name":"Centre for Tobacco Dependence, 3rd Medical Department, Department of Endocrinology and Metabolism, First Faculty of Medicine Charles University in Prague and General University Hospital in Prague  Czech Republic"},{"name":"Institute of Hygiene and Epidemiology, First Faculty of Medicine Charles University and General University Hospital Prague  Czech Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5408-0144","authenticated-orcid":false,"given":"Kamila","family":"Zvolska","sequence":"additional","affiliation":[{"name":"Centre for Tobacco Dependence, 3rd Medical Department, Department of Endocrinology and Metabolism, First Faculty of Medicine Charles University in Prague and General University Hospital in Prague  Czech Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4134-3870","authenticated-orcid":false,"given":"Alexandra","family":"Pankova","sequence":"additional","affiliation":[{"name":"Centre for Tobacco Dependence, 3rd Medical Department, Department of Endocrinology and Metabolism, First Faculty of Medicine Charles University in Prague and General University Hospital in Prague  Czech Republic"},{"name":"Institute of Hygiene and Epidemiology, First Faculty of Medicine Charles University and General University Hospital Prague  Czech Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zuzana","family":"Adamcekova","sequence":"additional","affiliation":[{"name":"Centre for Tobacco Dependence, 3rd Medical Department, Department of Endocrinology and Metabolism, First Faculty of Medicine Charles University in Prague and General University Hospital in Prague  Czech Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matyas","family":"Kuhn","sequence":"additional","affiliation":[{"name":"Institute of Biostatistics and Analyses at the Faculty of Medicine and the Faculty of Science Masaryk University  Brno Czech Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9184-0069","authenticated-orcid":false,"given":"Derek","family":"Noland","sequence":"additional","affiliation":[{"name":"Behavioral Health and Wellness Program University of Colorado  Anschutz Medical Campus Aurora CO USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,7,18]]},"reference":[{"key":"e_1_2_10_2_1","unstructured":"American Cancer Society. 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