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Self\u2010reported current (past 30\u00a0days) and computed cumulative life\u2010time marijuana use (one \u2018marijuana\u2010year\u2019 corresponds to 365\u00a0days of use) through assessments every 2\u20135\u00a0years. We fitted logistic regression models adjusting for sex, race, center, education, age, tobacco smoking, physical activity, alcohol use and body mass index.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Findings<\/jats:title>\n                    <jats:p>Among the 2585 participants with an ECG at year 20, mean age was 46, 57% were women, 45% were black; 83% had past exposure to marijuana and 11% were using marijuana currently. One hundred and seventy\u2010three participants (7%) had major abnormalities and 944 (37%) had minor abnormalities. Comparing current with never use in multivariable\u2010adjusted models, the odds ratio (OR) for major ECG abnormalities was 0.60 [95% confidence interval (CI)\u00a0=\u00a00.32\u20131.15] and for minor ECG abnormalities 1.21 (95% CI\u00a0=\u00a00.87\u20131.68). Results did not change after stratifying by sex and race. Cumulative marijuana use was not associated with ECG abnormalities.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>In a middle\u2010aged US population, life\u2010time cumulative and occasional current marijuana use were not associated with increases in electrocardiogram abnormalities. This adds to the growing body of evidence that occasional marijuana use and cardiovascular disease events and markers of subclinical atherosclerosis are not associated.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/add.15188","type":"journal-article","created":{"date-parts":[[2020,7,10]],"date-time":"2020-07-10T10:55:37Z","timestamp":1594378537000},"page":"583-595","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Association between marijuana use and electrocardiographic abnormalities by middle age: the Coronary Artery Risk Development in Young Adults (CARDIA) study"],"prefix":"10.1111","volume":"116","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8429-3231","authenticated-orcid":false,"given":"Julian","family":"Jakob","sequence":"first","affiliation":[{"name":"Institute of Primary Health Care (BIHAM) University of Bern  Bern, Switzerland"},{"name":"Department of Paediatrics University Hospital 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