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This laboratory study (2013\u201317) examined whether individual differences in perceived exposure to discrimination in one's daily life predicted tobacco withdrawal symptoms and smoking lapse behavior following acute tobacco deprivation in African American smokers.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>Mixed design with the between\u2010subjects continuous variable of perceived discrimination crossed with the within\u2010subject variable of tobacco deprivation status (deprived versus non\u2010deprived).<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>Academic medical center in Los Angeles, CA, USA.<\/jats:p><\/jats:sec><jats:sec><jats:title>Participants<\/jats:title><jats:p>African American non\u2010treatment seeking daily cigarette smokers (<jats:italic>n<\/jats:italic>\u00a0=\u00a0607, \u2265\u00a010 cig\/day).<\/jats:p><\/jats:sec><jats:sec><jats:title>Measurements<\/jats:title><jats:p>At a baseline visit, self\u2010reported frequency of perceived exposure to discrimination in one's daily life was measured [everyday discrimination scale (EDDS)]. At two subsequent counterbalanced experimental visits (16\u2010hour tobacco deprivation versus <jats:italic>ad\u2010libitum<\/jats:italic> smoking), self\u2010report assessments of various tobacco withdrawal symptom domains [Brief Questionnaire of Smoking Urges), Wisconsin Smoking Withdrawal Scale (WSWS), Profile of Mood States (POMS), Snaith\u2013Hamilton Pleasure Scale (SHAPS) and Current Impulsivity Scale (CIS)) and a behavioral smoking lapse analogue task were measured.<\/jats:p><\/jats:sec><jats:sec><jats:title>Findings<\/jats:title><jats:p>Adjusted models demonstrated that greater frequency of perceived exposure to discrimination was associated with larger deprivation\u2010induced increases in acute urges to smoke to alleviate negative mood, several negative mood states and subjective cognitive functioning\u2014effect sizes were small in magnitude (<jats:italic>\u03b2<\/jats:italic>s\u00a0=\u00a00.09\u20130.13; <jats:italic>P<\/jats:italic>s\u00a0&lt;\u00a00.02). Data were inconclusive for associations between perceived exposure to discrimination and deprivation\u2010induced changes in cravings, urges to smoke for pleasure, positive mood reduction, other symptoms or smoking reinstatement behavior.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Frequency of perceived exposure to discrimination appears to be modestly associated with increased severity of some deprivation\u2010induced tobacco withdrawal symptoms in African American smokers.<\/jats:p><\/jats:sec>","DOI":"10.1111\/add.15238","type":"journal-article","created":{"date-parts":[[2020,8,29]],"date-time":"2020-08-29T11:53:44Z","timestamp":1598702024000},"page":"914-925","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Association of frequency of perceived exposure to discrimination with tobacco withdrawal symptoms and smoking lapse behavior in African Americans"],"prefix":"10.1111","volume":"116","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5322-046X","authenticated-orcid":false,"given":"Mariel S.","family":"Bello","sequence":"first","affiliation":[{"name":"Department of Psychology University of Southern California  Los Angeles CA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Madalyn M.","family":"Liautaud","sequence":"additional","affiliation":[{"name":"Department of Preventive Medicine, Keck School of Medicine University of Southern California  Los Angeles CA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julianne T.","family":"De La Cerda","sequence":"additional","affiliation":[{"name":"Department of Preventive Medicine, Keck School of Medicine University of Southern California  Los Angeles CA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raina D.","family":"Pang","sequence":"additional","affiliation":[{"name":"Department of Preventive Medicine, Keck School of Medicine University of Southern California  Los Angeles CA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5734-9444","authenticated-orcid":false,"given":"Lara A.","family":"Ray","sequence":"additional","affiliation":[{"name":"Department of Psychology University of California Los Angeles  Los Angeles CA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jasjit A.","family":"Ahluwalia","sequence":"additional","affiliation":[{"name":"Department of Behavioral and Social Sciences Brown University School of Public Health  Providence RI USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1217-525X","authenticated-orcid":false,"given":"Adam M.","family":"Leventhal","sequence":"additional","affiliation":[{"name":"Department of Psychology University of Southern California  Los Angeles CA USA"},{"name":"Department of Preventive Medicine, Keck School of Medicine University of Southern California  Los Angeles CA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,10]]},"reference":[{"key":"e_1_2_8_2_1","unstructured":"SchoenbornC. 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