{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T21:14:33Z","timestamp":1791580473372,"version":"4.3.4"},"reference-count":32,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2021,1,11]],"date-time":"2021-01-11T00:00:00Z","timestamp":1610323200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["HHSN271201400028C"],"award-info":[{"award-number":["HHSN271201400028C"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["HHSN271201500065C"],"award-info":[{"award-number":["HHSN271201500065C"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["UG1DA040317"],"award-info":[{"award-number":["UG1DA040317"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Addiction"],"published-print":{"date-parts":[[2021,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background and Aims<\/jats:title>\n                    <jats:p>Physician and pharmacist collaboration may help address the shortage of buprenorphine\u2010waivered physicians and improve care for patients with opioid use disorder (OUD). This study investigated the feasibility and acceptability of a new collaborative care model involving buprenorphine\u2010waivered physicians and community pharmacists.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>Nonrandomized, single\u2010arm, open\u2010label feasibility trial.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting<\/jats:title>\n                    <jats:p>Three office\u2010based buprenorphine treatment (OBBT) clinics and three community pharmacies in the United States.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Participants<\/jats:title>\n                    <jats:p>Six physicians, six pharmacists, and 71 patients aged \u226518\u00a0years with Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM\u20105) OUD on buprenorphine maintenance.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Intervention<\/jats:title>\n                    <jats:p>After screening, eligible patients\u2019 buprenorphine care was transferred from their OBBT physician to a community pharmacist for 6\u00a0months.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Measurements<\/jats:title>\n                    <jats:p>Primary outcomes included recruitment, treatment retention and adherence, and opioid use. Secondary outcomes were intervention fidelity, pharmacists' use of prescription drug monitoring program (PDMP), participant safety, and satisfaction with treatment delivery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Findings<\/jats:title>\n                    <jats:p>A high proportion (93.4%, 71\/76) of eligible participants enrolled into the study. There were high rates of treatment retention (88.7%) and adherence (95.3%) at the end of the study. The proportion of opioid\u2010positive urine drug screens (UDSs) among complete cases (i.e. those with all six UDSs collected during 6\u00a0months) at month 6 was (4.9%, 3\/61). Intervention fidelity was excellent. Pharmacists used PDMP at 96.8% of visits. There were no opioid\u2010related safety events. Over 90% of patients endorsed that they were \u201cvery satisfied with their experience and the quality of treatment offered,\u201d that \u201ctreatment transfer from physician's office to the pharmacy was not difficult at all,\u201d and that \u201cholding buprenorphine visits at the same place the medication is dispensed was very or extremely useful\/convenient.\u201d Similarly, positive ratings of satisfaction were found among physicians\/pharmacists.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>A collaborative care model for people with opioid use disorder that involves buprenorphine\u2010waivered physicians and community pharmacists appears to be feasible to operate in the United States and have high acceptability to patients.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/add.15353","type":"journal-article","created":{"date-parts":[[2021,1,15]],"date-time":"2021-01-15T01:00:51Z","timestamp":1610672451000},"page":"1805-1816","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":55,"title":["Buprenorphine physician\u2013pharmacist collaboration in the management of patients with opioid use disorder: results from a multisite study of the National Drug Abuse Treatment Clinical Trials Network"],"prefix":"10.1111","volume":"116","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5909-2259","authenticated-orcid":false,"given":"Li\u2010Tzy","family":"Wu","sequence":"first","affiliation":[{"name":"Department of Psychiatry and Behavioral Sciences Duke University School of Medicine  Durham NC USA"},{"name":"Department of Medicine, Division of General Internal Medicine Duke University School of Medicine  Durham NC USA"},{"name":"Duke Clinical Research Institute Duke University School of Medicine  Durham NC USA"},{"name":"Center for Child and Family Policy, Sanford School of Public Policy Duke University  Durham NC USA"},{"name":"Duke Institute For Brain Sciences Duke University  Durham NC USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William S.","family":"John","sequence":"additional","affiliation":[{"name":"Department of Psychiatry and Behavioral Sciences Duke University School of Medicine  Durham NC USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9964-8066","authenticated-orcid":false,"given":"Udi E.","family":"Ghitza","sequence":"additional","affiliation":[{"name":"National Institute on Drug Abuse  Bethesda MD USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aimee","family":"Wahle","sequence":"additional","affiliation":[{"name":"The Emmes Company, LLC  Rockville MD USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abigail G.","family":"Matthews","sequence":"additional","affiliation":[{"name":"The Emmes Company, LLC  Rockville MD USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mitra","family":"Lewis","sequence":"additional","affiliation":[{"name":"The Emmes Company, LLC  Rockville MD USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brett","family":"Hart","sequence":"additional","affiliation":[{"name":"The Emmes Company, LLC  Rockville MD USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zach","family":"Hubbard","sequence":"additional","affiliation":[{"name":"The Emmes Company, LLC  Rockville MD USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lynn A.","family":"Bowlby","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of General Internal Medicine Duke University School of Medicine  Durham NC USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lawrence H.","family":"Greenblatt","sequence":"additional","affiliation":[{"name":"Department of Medicine, Division of General Internal Medicine Duke University School of Medicine  Durham NC USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7834-6138","authenticated-orcid":false,"given":"Paolo","family":"Mannelli","sequence":"additional","affiliation":[{"name":"Department of Psychiatry and Behavioral Sciences Duke University School of Medicine  Durham NC USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Pharm\u2010OUD\u2010Care Collaborative Investigators","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,1,11]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.7326\/M19-2403"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.drugalcdep.2016.10.015"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMp1402780"},{"key":"e_1_2_12_5_1","unstructured":"BlileyT.Drug Addiction Treatment Act of 2000. 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