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Participants could request cessation treatment at any time.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Measurements<\/jats:title>\n                    <jats:p>The primary outcome was 7\u2010day point\u2010prevalence abstinence at 52\u00a0weeks post enrollment; secondary outcomes were point\u2010prevalence abstinence at 26\u00a0weeks and making a quit attempt by weeks 26 and 52.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Findings<\/jats:title>\n                    <jats:p>\n                      No abstinence main effects were found but a mini\u2010lozenge \u00d7 reduction counseling \u00d7 BA interaction was found at 52\u00a0weeks;\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0=\u00a00.03. Unpacking this interaction showed that the mini\u2010lozenge alone produced the highest abstinence rate (16.7%); combining it with reduction counseling produced an especially low abstinence rate (4.1%). Reduction counseling decreased the likelihood of making a quit attempt by 52\u00a0weeks relative to no reduction counseling (\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0=\u00a00.01).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Nicotine mini\u2010lozenges may increase smoking abstinence in people initially unwilling to quit smoking, but their effectiveness declines when used with smoking reduction counseling or other behavioral interventions. Reduction counseling decreases the likelihood of making a quit attempt in people initially unwilling to quit smoking.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/add.15528","type":"journal-article","created":{"date-parts":[[2021,4,28]],"date-time":"2021-04-28T11:16:06Z","timestamp":1619608566000},"page":"3167-3179","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Evaluating four motivation\u2010phase intervention components for use with primary care patients unwilling to quit smoking: a randomized factorial experiment"],"prefix":"10.1111","volume":"116","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9631-6637","authenticated-orcid":false,"given":"Jessica W.","family":"Cook","sequence":"first","affiliation":[{"name":"Center for Tobacco Research and Intervention University of Wisconsin School of Medicine and Public Health  Madison WI USA"},{"name":"Department of Medicine University of Wisconsin School of Medicine and Public Health  Madison WI USA"},{"name":"William S. Middleton Memorial Veterans Hospital  Madison WI USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timothy B.","family":"Baker","sequence":"additional","affiliation":[{"name":"Center for Tobacco Research and Intervention University of Wisconsin School of Medicine and Public Health  Madison WI USA"},{"name":"Department of Medicine University of Wisconsin School of Medicine and Public Health  Madison WI USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael C.","family":"Fiore","sequence":"additional","affiliation":[{"name":"Center for Tobacco Research and Intervention University of Wisconsin School of Medicine and Public Health  Madison WI USA"},{"name":"Department of Medicine University of Wisconsin School of Medicine and Public Health  Madison WI USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4282-8722","authenticated-orcid":false,"given":"Linda M.","family":"Collins","sequence":"additional","affiliation":[{"name":"Department of Social and Behavioral Sciences, School of Global Public Health New York University  New York NY USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Megan E.","family":"Piper","sequence":"additional","affiliation":[{"name":"Center for Tobacco Research and Intervention University of Wisconsin School of Medicine and Public Health  Madison WI USA"},{"name":"Department of Medicine University of Wisconsin School of Medicine and Public Health  Madison WI USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4947-8051","authenticated-orcid":false,"given":"Tanya R.","family":"Schlam","sequence":"additional","affiliation":[{"name":"Center for Tobacco Research and Intervention University of Wisconsin School of Medicine and Public Health  Madison WI USA"},{"name":"Department of Medicine University of Wisconsin School of Medicine and Public Health  Madison WI USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel M.","family":"Bolt","sequence":"additional","affiliation":[{"name":"Department of Educational Psychology University of Wisconsin  WI USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stevens S.","family":"Smith","sequence":"additional","affiliation":[{"name":"Center for Tobacco Research and Intervention University of Wisconsin School of Medicine and Public Health  Madison WI USA"},{"name":"Department of Medicine University of Wisconsin School of Medicine and Public Health  Madison WI USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deejay","family":"Zwaga","sequence":"additional","affiliation":[{"name":"Center for Tobacco Research and Intervention University of Wisconsin School of Medicine and Public Health  Madison WI USA"},{"name":"Department of Medicine University of Wisconsin School of Medicine and Public Health  Madison WI USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Douglas E.","family":"Jorenby","sequence":"additional","affiliation":[{"name":"Center for Tobacco Research and Intervention University of Wisconsin School of Medicine and Public Health  Madison WI USA"},{"name":"Department of Medicine University of Wisconsin School of Medicine and Public Health  Madison WI USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robin","family":"Mermelstein","sequence":"additional","affiliation":[{"name":"Institute for Health Research and Policy University of Illinois at Chicago  Chicago IL USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,5,19]]},"reference":[{"key":"e_1_2_10_2_1","unstructured":"Centers for Disease Control and Prevention.Health effects of cigarette smoking202020 July2020. 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