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Primary outcome was SARS\u2010CoV\u20102 seroconversion since baseline, assessed with two SARS\u2010CoV\u20102 antibody tests, at baseline (September 2020) and end\u2010line (November 2020). Secondary outcomes were (a) self\u2010reported new SARS\u2010CoV\u20102 infection at the study end\u2010line and (b) self\u2010reported symptomatic COVID\u201019 at baseline.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Findings<\/jats:title>\n                    <jats:p>Prevalence of high\u2010risk alcohol consumption was 32 %. In models adjusted for demographics, students with high\u2010risk alcohol consumption status had 2.44 [95% confidence interval (CI)\u2009=\u20091.35, 4.25] times the risk of SARS\u2010CoV\u20102 seroconversion and 1.84 (95% CI\u2009=\u20091.04, 3.28) times the risk of self\u2010reporting a positive SARS\u2010CoV\u20102 infection, compared with students with no such risk. We did not identify any association between high\u2010risk alcohol consumption and symptomatic COVID\u201019 (prevalence ratio\u2009=\u20091.17, 95% CI\u2009=\u20090.93, 1.47). Findings from sensitivity analyses corroborated these results and suggested potential for a dose\u2013response relationship.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Among American college students, high\u2010risk alcohol consumption appears to be associated with higher risk for severe acute respiratory syndrome coronavirus 2 seroconversion\/infection.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/add.15835","type":"journal-article","created":{"date-parts":[[2022,2,7]],"date-time":"2022-02-07T05:16:00Z","timestamp":1644210960000},"page":"1908-1919","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":12,"title":["Relationship between high\u2010risk alcohol consumption and severe acute respiratory syndrome coronavirus 2 (SARS\u2010CoV\u20102) seroconversion: a prospective sero\u2010epidemiological cohort study among American college students"],"prefix":"10.1111","volume":"117","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0950-2675","authenticated-orcid":false,"given":"Sina","family":"Kianersi","sequence":"first","affiliation":[{"name":"Department of Epidemiology and Biostatistics Indiana University School of Public Health\u2010Bloomington  Bloomington IN USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0779-810X","authenticated-orcid":false,"given":"Christina","family":"Ludema","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Biostatistics Indiana University School of Public Health\u2010Bloomington  Bloomington IN USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2925-8585","authenticated-orcid":false,"given":"Jonathan T.","family":"Macy","sequence":"additional","affiliation":[{"name":"Department of Applied Health Science Indiana University School of Public Health\u2010Bloomington  Bloomington IN USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chen","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Biostatistics Indiana University School of Public Health\u2010Bloomington  Bloomington IN USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6679-6791","authenticated-orcid":false,"given":"Molly","family":"Rosenberg","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Biostatistics Indiana University School of Public Health\u2010Bloomington  Bloomington IN USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,2,22]]},"reference":[{"key":"e_1_2_11_2_1","unstructured":"The New York Times. 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