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Lab\u2010based studies have investigated the alcohol priming effect; however, heterogeneity in designs has resulted in some inconsistent findings. The aims of this meta\u2010analysis were to (i) determine the pooled effect size for motivation to drink following priming, measured by alcohol consumption and craving, and (ii) examine whether design characteristics influenced any priming effect.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Literature searches of PsycINFO, PubMed and Scopus in October 2020 (updated October 2021) identified lab\u2010based alcohol priming studies that assessed effect of priming on motivation to drink. A tailored risk\u2010of\u2010bias tool assessed quality of lab\u2010based studies. Random effects meta\u2010analyses were computed on outcome data from 38 studies comparing the effect of a priming dose of alcohol against control on subsequent alcohol consumption\/self\u2010reported craving. Study characteristics that might have affected outcomes were design type (within\/between\u2010participant), dose of prime, time of motivation assessment, type of control drink (placebo alcohol\/soft drink).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Relative to control, alcohol had a small\u2010to\u2010moderate priming effect on subsequent alcohol consumption (standardised mean difference [SMD]\u2009=\u20090.336 [95% CI, 0.171, 0.500]) and craving (SMD\u2009=\u20090.431 [95% CI, 0.306, 0.555]). Aspects of study design differentially affected consumption and craving. The size of the priming dose had no effect on consumption, but larger doses were sometimes associated with greater craving (with craving generally following the blood alcohol curve). Alcohol priming effects for consumption, but not craving, were smaller when compared with placebo, relative to soft drink, control.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Lab\u2010based alcohol priming studies are a valid paradigm from which to investigate the impact of acute intoxication on alcohol motivation. Designs are needed that assess the impact of acute consumption on motivation to drink in more varied and realistic ways.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/add.15962","type":"journal-article","created":{"date-parts":[[2022,5,31]],"date-time":"2022-05-31T04:49:08Z","timestamp":1653972548000},"page":"2986-3003","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["The impact of alcohol priming on craving and motivation to drink: a meta\u2010analysis"],"prefix":"10.1111","volume":"117","author":[{"given":"Lauren","family":"Halsall","sequence":"first","affiliation":[{"name":"Department of Psychology, Institute of Population Health University of Liverpool  Liverpool United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5951-889X","authenticated-orcid":false,"given":"Andrew","family":"Jones","sequence":"additional","affiliation":[{"name":"Department of Psychology, Institute of Population Health University of Liverpool  Liverpool United Kingdom"},{"name":"Liverpool Centre for Alcohol Research  Liverpool United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4275-601X","authenticated-orcid":false,"given":"Carl","family":"Roberts","sequence":"additional","affiliation":[{"name":"Department of Psychology, Institute of Population Health University of Liverpool  Liverpool United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9974-834X","authenticated-orcid":false,"given":"Graeme","family":"Knibb","sequence":"additional","affiliation":[{"name":"Department of Psychology Edge Hill University  Ormskirk United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3267-7318","authenticated-orcid":false,"given":"Abigail K.","family":"Rose","sequence":"additional","affiliation":[{"name":"Liverpool Centre for Alcohol Research  Liverpool United Kingdom"},{"name":"School of Psychology Liverpool John Moore's University  Liverpool United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,6,21]]},"reference":[{"key":"e_1_2_9_2_1","unstructured":"Organisation WH.Global status report on alcohol and health 2018. 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