{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T15:35:13Z","timestamp":1784561713667,"version":"3.55.0"},"reference-count":16,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2023,6,7]],"date-time":"2023-06-07T00:00:00Z","timestamp":1686096000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000026","name":"National Institute on Drug Abuse","doi-asserted-by":"publisher","award":["R01DA001411"],"award-info":[{"award-number":["R01DA001411"]}],"id":[{"id":"10.13039\/100000026","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000026","name":"National Institute on Drug Abuse","doi-asserted-by":"publisher","award":["R01DA016575"],"award-info":[{"award-number":["R01DA016575"]}],"id":[{"id":"10.13039\/100000026","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["pericles.pericles-gcp.literatumonline.com"],"crossmark-restriction":true},"short-container-title":["Addiction"],"published-print":{"date-parts":[[2023,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background and aims<\/jats:title><jats:p>Given the shifting landscape of hallucinogen use, particularly with increased therapeutic use, understanding current changes in use is a necessary part of examining the potential risk hallucinogens pose to vulnerable populations, such as young adults. This study aimed to measure hallucinogen use among young adults aged 19\u201330\u2009years from 2018 to 2021.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design, setting and participants<\/jats:title><jats:p>This was a longitudinal cohort study among young adults aged 19\u201330\u2009years from the US general population, interviewed between 2018 and 2021. Participants comprised 11\u00a0304 unique respondents, with an average number of follow\u2010ups of 1.46 (standard deviation\u2009=\u20090.50). Of the observed data points, 51.9% were among females.<\/jats:p><\/jats:sec><jats:sec><jats:title>Measurements<\/jats:title><jats:p>We examined past 12\u2010month self\u2010reported use of lysergic acid diethylamide (LSD), as well as hallucinogens besides LSD (e.g. psilocybin), monitoring any use as well as frequency, overall and by sex.<\/jats:p><\/jats:sec><jats:sec><jats:title>Findings<\/jats:title><jats:p>From 2018 to 2021, past 12\u2010month use of LSD among young adults in the US remained relatively unchanged, from 3.7% [95% confidence interval (CI)\u2009=\u20093.1\u20134.3] in 2018 to 4.2% in 2021 (95% CI\u2009=\u20093.4\u20135.0). Non\u2010LSD hallucinogen [e.g. \u2018shrooms\u2019, psilocybin or PCP (phenylcyclohexyl piperidine)] use, however, increased in prevalence from 3.4% (95% CI\u2009=\u20092.8\u20134.1) to 6.6% from 2018 to 2021 (95% CI\u2009=\u20095.5\u20137.6). Across years, the odds of non\u2010LSD use were higher for males [odds ratio (OR)\u2009=\u20091.86, 95% CI\u2009=\u20091.52\u20132.26] and lower for black than white participants (OR\u2009=\u20090.29, 95% CI\u2009=\u20090.19\u20130.47) and those without a college\u2010educated parent (OR\u2009=\u20090.80, 95% CI\u2009=\u20090.64\u20130.99). Demographic disparities were similar for LSD use.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Prevalence of past\u2010year use non\u2010lysergic acid diethylamide (LSD) hallucinogen was twice as high in 2021 as in 2018 among US young adults. Correlates of non\u2010LSD hallucinogen use included being male, white and from higher socio\u2010economic status backgrounds.<\/jats:p><\/jats:sec>","DOI":"10.1111\/add.16259","type":"journal-article","created":{"date-parts":[[2023,6,8]],"date-time":"2023-06-08T04:01:21Z","timestamp":1686196881000},"page":"2449-2454","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":42,"title":["Hallucinogen use among young adults ages 19\u201330 in the United States: Changes from 2018 to 2021"],"prefix":"10.1111","volume":"118","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5624-021X","authenticated-orcid":false,"given":"Katherine M.","family":"Keyes","sequence":"first","affiliation":[{"name":"Department of Epidemiology, Mailman School of Public Health Columbia University  New York NY USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3594-4944","authenticated-orcid":false,"given":"Megan E.","family":"Patrick","sequence":"additional","affiliation":[{"name":"Survey Research Center, Institute for Social Research University of Michigan  Ann Arbor MI USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,6,7]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.addbeh.2018.09.020"},{"key":"e_1_2_9_3_1","series-title":"Monitoring the Future Monograph Series","volume-title":"Monitoring the Future Panel Study Annual Report: National Data on Substance Use among Adults Ages 19 to 60, 1976\u20132021","author":"Patrick ME","year":"2022"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/add.15987"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.psychres.2020.112749"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.drugalcdep.2020.108071"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.abrep.2022.100454"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1177\/13634615221129115"},{"key":"e_1_2_9_9_1","series-title":"Monitoring the Future Monograph Series","volume-title":"An updated weighting strategy for the monitoring the future panel study","author":"Patrick ME","year":"2022"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.15288\/jsad.2012.73.772"},{"key":"e_1_2_9_11_1","series-title":"Secondary School Students. 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