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When the monograph came to the attention of the authors in 2006, there existed no known translation of it in any modern language. In 2014, it was translated and published in French. This paper analyses the monograph\u2019s key content elements and its place in the history of the concept of addiction.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A contextual analysis of the late Italian Renaissance, followed by key excerpts from the text and commentaries on the meaning and significance of the monograph.<\/jats:p><\/jats:sec><jats:sec><jats:title>Findings and conclusions<\/jats:title><jats:p>Pascasius Justus Turq\u2019s 1561 monograph on pathological gambling outlines a disease view of gambling, identifies cognitive processes and biological vulnerabilities as aetiological factors, avoids religious or moral judgements and recommends cognitive treatment to change the beliefs and expectancies of gamblers. This study shows that a \u2018disease formulation\u2019 of addiction was enunciated as early as the 16th century, and its contemporary resonance suggests that current clinical features of addictive disorders have existed for centuries.<\/jats:p><\/jats:sec>","DOI":"10.1111\/add.16298","type":"journal-article","created":{"date-parts":[[2023,7,22]],"date-time":"2023-07-22T07:36:40Z","timestamp":1690011400000},"page":"2235-2241","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Addiction: A treatise from 1561"],"prefix":"10.1111","volume":"118","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3340-8614","authenticated-orcid":false,"given":"Louise","family":"Nadeau","sequence":"first","affiliation":[{"name":"Department of Psychology Universit\u00e9 de Montr\u00e9al Montr\u00e9al QC Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marc","family":"Valleur","sequence":"additional","affiliation":[{"name":"H\u00f4pital Marmottan Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,7,22]]},"reference":[{"key":"e_1_2_13_2_1","volume-title":"Alea sive de curanda ludendi in pecuniam cupiditate: Die zwei B\u00fccher des P\u00e2quier Joostens aus Eeklo, Doktors der Philosophie und der Medizin \u00fcber das Gl\u00fccksspiel oder Die Heilung der Spielleidenschaft","author":"Kronegger\u2010Roth SV","year":"2014"},{"key":"e_1_2_13_3_1","doi-asserted-by":"crossref","DOI":"10.1515\/9782760633445","volume-title":"Pascasius ou comprendre les addictions","author":"Nadeau L","year":"2014"},{"key":"e_1_2_13_4_1","unstructured":"D\u2019EekloPJ.Alea Sive De Curanda in pecuniam ludendi cupiditate libri duo.Amsterdam Nethelands:Elsevier;1642."},{"key":"e_1_2_13_5_1","first-page":"2","volume-title":"Res publica litterarum. 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