{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,6]],"date-time":"2026-07-06T20:26:58Z","timestamp":1783369618848,"version":"3.54.6"},"reference-count":31,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2023,8,13]],"date-time":"2023-08-13T00:00:00Z","timestamp":1691884800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003554","name":"Lundbeck Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003554","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["pericles.pericles-gcp.literatumonline.com"],"crossmark-restriction":true},"short-container-title":["Addiction"],"published-print":{"date-parts":[[2023,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background and aims<\/jats:title><jats:p>Substance\u2010induced psychosis has previously been linked to an excess risk of suicide; however, the association between substance\u2010induced psychosis and suicide attempt has hitherto not been investigated. We investigated whether substance\u2010induced psychosis was associated with a higher risk of subsequent suicide attempt.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>Nation\u2010wide prospective register\u2010based cohort study.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>Denmark.<\/jats:p><\/jats:sec><jats:sec><jats:title>Participants<\/jats:title><jats:p>All people living in Denmark aged 13\u2009years or more during 1995 to 2017.<\/jats:p><\/jats:sec><jats:sec><jats:title>Measurements<\/jats:title><jats:p>Substance\u2010induced psychosis and suicide attempts were identified through hospital records as ICD\u201010 codes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Findings<\/jats:title><jats:p>A total of 8900 (78.8% males) individuals were diagnosed with a substance\u2010induced psychosis, and 740 of these had a suicide attempt during follow\u2010up. People with a substance\u2010induced psychosis had a higher risk of a subsequent suicide attempt [hazard ratio (HR)\u2009=\u200913.4, 95% confidence interval (CI)\u2009=\u200912.4\u201314.4] when compared with the general population. The highest hazard ratios were found for psychosis induced by opioids (HR\u2009=\u200926.4, 95% CI\u2009=\u200918.2\u201338.2); alcohol (HR\u2009=\u200917.7, 95% CI\u2009=\u200915.2\u201320.6); sedatives (HR\u2009=\u200917.2, 95% CI\u2009=\u20098.9\u201333.0); and cocaine (HR\u2009=\u200915.6, 95% CI\u2009=\u200910.7\u201322.8), while cannabis\u2010induced psychosis was linked to an HR of 8.9 (95% CI\u2009=\u20097.7\u201310.3). Approximately 15% of patients with substance\u2010induced psychosis had had a suicide attempt within 20\u2009years of their substance\u2010induced psychosis diagnosis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>In Denmark, substance\u2010induced psychosis appears to be strongly associated with subsequent suicide attempt, underscoring the importance of attention and better follow\u2010up for this patient group.<\/jats:p><\/jats:sec>","DOI":"10.1111\/add.16311","type":"journal-article","created":{"date-parts":[[2023,8,14]],"date-time":"2023-08-14T03:09:46Z","timestamp":1691982586000},"page":"2440-2448","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Association between substance\u2010induced psychosis and suicide attempt: A Danish nation\u2010wide register\u2010based study"],"prefix":"10.1111","volume":"118","author":[{"given":"Solvejg Dam","family":"Munch","sequence":"first","affiliation":[{"name":"Copenhagen Research Center for Mental Health\u2014CORE, Mental Health Center Copenhagen Mental Health Services in the Capital Region of Denmark  Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Trine","family":"Madsen","sequence":"additional","affiliation":[{"name":"Copenhagen Research Center for Mental Health\u2014CORE, Mental Health Center Copenhagen Mental Health Services in the Capital Region of Denmark  Copenhagen Denmark"},{"name":"Danish Research Institute of Suicide Prevention Mental Health Center Copenhagen  Copenhagen Denmark"},{"name":"Department of Public Health, Section of Epidemiology University of Copenhagen  Copenhagen Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Merete","family":"Nordentoft","sequence":"additional","affiliation":[{"name":"Copenhagen Research Center for Mental Health\u2014CORE, Mental Health Center Copenhagen Mental Health 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