{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,10]],"date-time":"2026-11-10T21:07:49Z","timestamp":1794344869237,"version":"4.9.0"},"reference-count":48,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2023,9,24]],"date-time":"2023-09-24T00:00:00Z","timestamp":1695513600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100011000","name":"Mission Interminist\u00e9rielle de Lutte Contre les Drogues et les Conduites Addictives","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100011000","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001677","name":"Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001677","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Addiction"],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aims<\/jats:title><jats:p>The primary aim of this study was to evaluate the impact of drug consumption rooms (DCRs) in France on injection equipment\u2010sharing, while the secondary aims focused upon their impact on access to hepatitis C virus (HCV) testing and opioid agonist treatment (OAT).<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>The COhort to identify Structural and INdividual factors associated with drug USe (COSINUS cohort) was a 12\u2010month longitudinal study of 665 people who inject drugs (PWID), conducted in Bordeaux, Marseille, Paris and Strasbourg. We used data from face\u2010to\u2010face interviews at enrolment and at 6\u2010month and 12\u2010month visits.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting and participants<\/jats:title><jats:p>The participants were recruited in harm reduction programmes in Bordeaux and Marseille and in DCRs in Strasbourg and Paris. Participants were aged more than 18\u2009years, French\u2010speaking and had injected substances the month before enrolment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Measurements<\/jats:title><jats:p>We measured the impact of DCR exposure on injection equipment sharing, HCV testing and the use of medications for opioid use disorder, after adjustment for significant correlates. We used a two\u2010step Heckman mixed\u2010effects probit model, which allowed us to take into account the correlation of repeated measures and to control for potential bias due to non\u2010randomization between the two groups (DCR\u2010exposed versus DCR\u2010unexposed participants).<\/jats:p><\/jats:sec><jats:sec><jats:title>Findings<\/jats:title><jats:p>The difference of declared injection equipment sharing between PWID exposed to DCRs versus non\u2010exposed was 10% (1% for those exposed versus 11% for those non\u2010exposed, marginal effect\u2009=\u2009\u22120.10; 95% confidence interval\u2009=\u2009\u22120.18, \u22120.03); there was no impact of DCRs on HCV testing and OAT.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>In the French context, drug consumption rooms appear to have a positive impact on at\u2010risk practices for infectious diseases such as human immunodeficiency virus (HIV) and hepatitis C virus.<\/jats:p><\/jats:sec>","DOI":"10.1111\/add.16320","type":"journal-article","created":{"date-parts":[[2023,9,25]],"date-time":"2023-09-25T06:14:21Z","timestamp":1695622461000},"page":"180-199","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Drug consumption rooms are effective to reduce at\u2010risk practices associated with HIV\/HCV infections among people who inject drugs: Results from the COSINUS cohort study"],"prefix":"10.1111","volume":"119","author":[{"given":"Laurence","family":"Lalanne","sequence":"first","affiliation":[{"name":"INSERM 1114, Department of Psychiatry and Addictology University Hospital of Strasbourg, F\u00e9d\u00e9ration de M\u00e9decine Translationnelle de Strasbourg (FMTS)  Strasbourg France"},{"name":"Department of Psychiatry and Addictology University Hospital of Strasbourg, F\u00e9d\u00e9ration de M\u00e9decine Translationnelle de Strasbourg (FMTS)  Strasbourg France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5069-4982","authenticated-orcid":false,"given":"Perrine","family":"Roux","sequence":"additional","affiliation":[{"name":"Aix Marseille Univ, INSERM, IRD, SESSTIM, Sciences Economiques &amp; Sociales de la Sant\u00e9 &amp; Traitement de l'Information M\u00e9dicale, ISSPAM  Marseille France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C\u00e9cile","family":"Donadille","sequence":"additional","affiliation":[{"name":"Aix Marseille Univ, INSERM, IRD, SESSTIM, Sciences Economiques &amp; Sociales de la Sant\u00e9 &amp; Traitement de l'Information M\u00e9dicale, ISSPAM  Marseille France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laelia","family":"Briand Madrid","sequence":"additional","affiliation":[{"name":"Aix Marseille Univ, INSERM, IRD, SESSTIM, Sciences Economiques &amp; Sociales de la Sant\u00e9 &amp; Traitement de l'Information M\u00e9dicale, ISSPAM  Marseille France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabelle","family":"C\u00e9lerier","sequence":"additional","affiliation":[{"name":"ORS PACA, Observatoire r\u00e9gional de la sant\u00e9 Provence\u2010Alpes\u2010C\u00f4te d'Azur  Marseille France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carole","family":"Chauvin","sequence":"additional","affiliation":[{"name":"Centre d'\u00e9tude des Mouvements Sociaux (Inserm U1276\/CNRS UMR8044\/EHESS)  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naomi","family":"Hamelin","sequence":"additional","affiliation":[{"name":"INSERM 1114, Department of Psychiatry and Addictology University Hospital of Strasbourg, F\u00e9d\u00e9ration de M\u00e9decine Translationnelle de Strasbourg (FMTS)  Strasbourg France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charlotte","family":"Kervran","sequence":"additional","affiliation":[{"name":"Addiction Team, SANPSY, CNRS UMR 6033  Bordeaux France"},{"name":"CH Charles Perrens and CHU de Bordeaux P\u00f4le inter\u2010\u00e9tablissement Addictologie  Bordeaux France"},{"name":"Universit\u00e9 Bordeaux  Bordeaux France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gwena\u00eblle","family":"Maradan","sequence":"additional","affiliation":[{"name":"ORS PACA, Observatoire r\u00e9gional de la sant\u00e9 Provence\u2010Alpes\u2010C\u00f4te d'Azur  Marseille France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8938-8683","authenticated-orcid":false,"given":"Marc","family":"Auriacombe","sequence":"additional","affiliation":[{"name":"Addiction Team, SANPSY, CNRS UMR 6033  Bordeaux France"},{"name":"CH Charles Perrens and CHU de Bordeaux P\u00f4le inter\u2010\u00e9tablissement Addictologie  Bordeaux France"},{"name":"Universit\u00e9 Bordeaux  Bordeaux France"},{"name":"Department of Psychiatry, Perelman School of Medicine 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