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This particulate material will naturally pass to the lungs where it will be largely filtered out in the pulmonary vascular bed, and in turn, it can result in a range of pathological processes in the lungs including pulmonary arterial hypertension, granulomatous lung disease, and pulmonary fibrosis. On rare occasions, a rapid increase in pulmonary vascular resistance can result in sudden death of the injecting drug user.<\/jats:p>","DOI":"10.1111\/add.70012","type":"journal-article","created":{"date-parts":[[2025,2,6]],"date-time":"2025-02-06T03:35:56Z","timestamp":1738812956000},"page":"1276-1279","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Rare but relevant: The injection of tablet preparations and pulmonary hypertension"],"prefix":"10.1111","volume":"120","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5863-635X","authenticated-orcid":false,"given":"Johan","family":"Duflou","sequence":"first","affiliation":[{"name":"National Drug and Alcohol Research Centre, UNSW Sydney  Sydney Australia"},{"name":"Sydney Medical School The University of Sydney  Sydney Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,2,6]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.2174\/157488612803251298"},{"volume-title":"Non\u2010medical and illicit use of psychoactive drugs","year":"2017","author":"McLean S","key":"e_1_2_9_3_1"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1201\/b18962"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/0013-9351(80)90011-0"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.revmed.2018.03.017"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005792-197905000-00003"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-642-20659-7"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1972.03200210053014"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/add.12930"},{"volume-title":"Sydney: national drug and alcohol research Centre","year":"2014","author":"Peacock A","key":"e_1_2_9_11_1"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(21)02252-2"},{"key":"e_1_2_9_13_1","unstructured":"Endone.MIMS Online. 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