{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,19]],"date-time":"2026-03-19T19:02:29Z","timestamp":1773946949136,"version":"3.50.1"},"reference-count":35,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T00:00:00Z","timestamp":1762819200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T00:00:00Z","timestamp":1762819200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Addiction"],"published-print":{"date-parts":[[2026,3]]},"abstract":"Abstract<\/jats:title>\n \n Background and aims<\/jats:title>\n Smoking is the leading preventable cause of premature death in China, yet less than 10% of smokers seeking to quit receive treatment. This study aimed to test the efficacy of a cognitive behavioral therapy (CBT)\u2010based smoking cessation intervention (\u2018Smokefree Life\u2019) via a smartphone app in China.<\/jats:p>\n <\/jats:sec>\n \n Design<\/jats:title>\n A digital, parallel, single\u2010blind, two\u2010arm (1:1) randomized controlled trial.<\/jats:p>\n <\/jats:sec>\n \n Setting<\/jats:title>\n This trial was conducted via \u2018Smokefree Life\u2019 app in the whole of mainland of China between 13 December 2021 and 15 April 2023.<\/jats:p>\n <\/jats:sec>\n \n Participants<\/jats:title>\n Chinese\u2010speaking adult smokers (925 males, 102 females, mean age 35.0\u2009\u00b1\u20096.7) willing to quit within one month were recruited via WeChat, survey sampling and referral from doctors, friends and family and randomized in a 1:1 ratio.<\/jats:p>\n <\/jats:sec>\n \n Intervention<\/jats:title>\n \n The intervention group (\n n<\/jats:italic>\n \u2009=\u2009523) received a 13\u201314\u2009week CBT\u2010based smoking cessation intervention via smartphone app and the control group (\n n<\/jats:italic>\n \u2009=\u2009504) received only control messages. All participants were followed for 26\u2009weeks post\u2010quit date.\n <\/jats:p>\n <\/jats:sec>\n \n Measurements<\/jats:title>\n The primary outcome was biochemically validated continuous abstinence at 26\u2009weeks. Secondary outcomes were self\u2010reported 7\u2010day abstinence and continuous abstinence at 26\u2009weeks.<\/jats:p>\n <\/jats:sec>\n \n Findings<\/jats:title>\n \n By intention\u2010to\u2010treat analysis, the biochemically verified 26\u2010week continuous abstinence rate was statistically significantly higher in the intervention group (6.50%) compared with the control group (2.58%) (odds ratio\u2009=\u20092.63, 95% confidence interval = 1.40\u20135.22,\n P<\/jats:italic>\n \u2009=\u20090.0037). Self\u2010reported 7\u2010day and continuous abstinence rates were also consistently higher in the intervention group across follow\u2010ups (all\n P<\/jats:italic>\n \u2009<\u20090.05).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n The \u2018Smokefree Life\u2019 app\u2010based smoking cessation intervention statistically significantly improved 6\u2010month biochemically confirmed quit rates among adult smokers in China.<\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/add.70239","type":"journal-article","created":{"date-parts":[[2025,11,12]],"date-time":"2025-11-12T02:30:24Z","timestamp":1762914624000},"page":"575-585","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Efficacy of cognitive behavioral therapy\u2010based smartphone app for smoking cessation in China: A randomized controlled trial"],"prefix":"10.1111","volume":"121","author":[{"given":"Jinsong","family":"Tang","sequence":"first","affiliation":[{"name":"Department of Psychiatry Sir Run Run Shaw Hospital, Zhejiang University School of Medicine Zhejiang China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaocong","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Big Data in Health Science School of Public Health Zhejiang University School of Medicine Zhejiang China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shanshan","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Psychiatry Sir Run Run Shaw Hospital, Zhejiang University School of Medicine Zhejiang China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yunkai","family":"Sun","sequence":"additional","affiliation":[{"name":"Department of Psychiatry Sir Run Run Shaw Hospital, Zhejiang University School of Medicine Zhejiang 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