{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T04:04:34Z","timestamp":1783915474487,"version":"3.55.0"},"reference-count":23,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T00:00:00Z","timestamp":1779235200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T00:00:00Z","timestamp":1779235200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100007165","name":"University of Missouri","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007165","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Addiction"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background and aims<\/jats:title>\n                    <jats:p>Memory loss from alcohol use (\u2018blackout\u2019) is a prevalent and costly indicator of substance\u2010related harm. While alcohol\u2010induced blackouts can be assessed retrospectively via self\u2010report, no tool exists to identify blackouts objectively in real time, hindering progress in research as well as intervention efforts. This study tested the feasibility and diagnostic accuracy of real\u2010time memory tasks in identifying alcohol\u2010induced blackouts in situ.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>Prospective diagnostic study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting<\/jats:title>\n                    <jats:p>United States.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Participants<\/jats:title>\n                    <jats:p>\n                      Young adults (18\u201330 years of age;\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200963) reporting recurrent memory loss as a result of alcohol use were recruited from across the United States between December 2022 and January 2024.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Measurements<\/jats:title>\n                    <jats:p>Participants completed a baseline survey and orientation interview, followed by 30\u2009days of ecological momentary assessments (EMA). EMA included recall and recognition tests for visual stimuli during drinking events (index tests) and subsequent self\u2010reports of blackout (reference standard). At the end of the protocol, participants also completed a Timeline Followback interview of blackout events during the assessment period. Primary outcomes, which were specified prior to data collection, were (a) feasibility of memory task completion during drinking events and (b) diagnostic accuracy of memory tasks in identifying blackout at the event level. Data were analyzed using Bayesian logistic multilevel models.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Findings<\/jats:title>\n                    <jats:p>Of the 63 participants included [mean age\u2009=\u200923.2, standard deviation (SD)\u2009=\u20093.3; 78% female, 51% White], 38 (60%) self\u2010reported a blackout during the assessment protocol. On average, participants completed 85% of memory tests prompted (SD\u2009=\u200916.42). Within days, both greater\u2010than\u2010average number of drinks [odds ratio (OR)\u2009=\u20091.74;\u00a095% confidence interval (CI) = 1.41\u20132.19] and failure of 1\u2009+\u2009recall memory test (OR\u2009=\u200915.53; 95% CI = 5.96\u201336.27) were associated with increased odds of blackout. In model\u2010predicted probabilities, blackout probability was ~0.01 if a person consumed their average number of drinks, ~0.21 if they had five more drinks than average and ~0.34 if they failed 1\u2009+\u2009recall test. Participants self\u2010reported blackout on 39% of the days that they failed 1\u2009+\u2009recall memory test (positive predictive value; 95% CI = 30\u201349); however, they reported not having a blackout on 92% of days that they correctly recalled all memory tests (negative predictive value; 95% CI = 89\u201395).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Objective measures of alcohol\u2010induced blackout can be implemented in real\u2010life contexts. Failing a visual memory test while intoxicated is not necessarily indicative of blackout; however, correct recall indicates that blackout is highly unlikely.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/add.70446","type":"journal-article","created":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T13:00:46Z","timestamp":1779282046000},"page":"2166-2175","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Predictive value of real\u2010time memory tests in identifying alcohol\u2010induced blackouts in situ"],"prefix":"10.1111","volume":"121","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0624-1414","authenticated-orcid":false,"given":"Mary Beth","family":"Miller","sequence":"first","affiliation":[{"name":"Department of Psychiatry University of Missouri  Columbia MO USA"},{"name":"Department of Psychological Sciences University of Missouri  Columbia MO USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4286-7070","authenticated-orcid":false,"given":"Sydney D.","family":"Shoemaker","sequence":"additional","affiliation":[{"name":"Department of Psychological Sciences University of Missouri  Columbia MO USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lindsey K.","family":"Freeman","sequence":"additional","affiliation":[{"name":"Department of Psychological Sciences University of Missouri  Columbia MO USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2311-5674","authenticated-orcid":false,"given":"Ashley F.","family":"Curtis","sequence":"additional","affiliation":[{"name":"College of Nursing University of South Florida  Tampa FL USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8310-140X","authenticated-orcid":false,"given":"Jennifer E.","family":"Merrill","sequence":"additional","affiliation":[{"name":"Center for Alcohol and Addiction Studies Brown University  Providence RI USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edgar C.","family":"Merkle","sequence":"additional","affiliation":[{"name":"Department of Psychological Sciences University of Missouri  Columbia MO USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,5,20]]},"reference":[{"issue":"2","key":"e_1_2_10_2_1","first-page":"186","article-title":"What happened? 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