{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T05:07:20Z","timestamp":1789535240260,"version":"build-2803163510"},"reference-count":53,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T00:00:00Z","timestamp":1780444800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T00:00:00Z","timestamp":1780444800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Addiction"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background and aims<\/jats:title>\n                    <jats:p>Increased risk of alcohol dependence is recognised following bariatric surgery. Modified gastrointestinal anatomy and neurohormonal profiles lead to altered alcohol metabolism, peak blood alcohol concentrations and enhanced reward circuits and cravings. For patients with metabolic associated fatty liver disease, bariatric surgery has been shown to reduce liver fibrosis; however, the impact of bariatric surgery on alcohol consumption and consequent liver fibrosis has not been well\u2010characterised using validated measures. This study examined the changes in alcohol consumption patterns, alcohol dependence and validated liver fibrosis measures before and after bariatric surgery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design, setting and participants<\/jats:title>\n                    <jats:p>A retrospective cohort study assessing patients seeking treatment for alcohol problems with a history of gastric sleeve (GS) or Roux\u2010en\u2010Y Gastric Bypass (RYGB) in a quaternary hospital in Brisbane, Australia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Measurements<\/jats:title>\n                    <jats:p>Validated measures of alcohol dependence [Alcohol Use Disorders Identification Test (AUDIT) and brief Michigan Alcohol Screening Test (bMAST)] and non\u2010invasive liver fibrosis (FIB4 and APRI) were compared pre\u2010 and post\u2010surgery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Findings<\/jats:title>\n                    <jats:p>\n                      Twenty patients were identified with prior GS and 10 patients with RYGB. Following bariatric surgery, body mass index was reduced by 14.5 (\u00b19.39) kg\/m\n                      <jats:sup>2<\/jats:sup>\n                      . Metabolic co\u2010morbidities were less frequent post\u2010surgery. Pre\u2010surgery, the mean AUDIT score was 10.2\u2009\u00b1\u20098.9, with 9 patients having scores indicative of alcohol dependence. Mean AUDIT increased statistically significantly post\u2010surgery (18.1, standard deviation \u00b111.4;\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u20090.001) with 29 patients meeting criteria for alcohol dependence. AUDIT components relating to both consumption (volume, frequency) and harmful consequences of alcohol increased following surgery. Despite surgery lowering metabolic liver fibrosis risk, worsened liver fibrosis was observed [mean FIB4 (0.98\u2009\u00b1\u20091.8) and APRI (0.41\u2009\u00b1\u20090.83) increased;\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u20090.05].\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Within a cohort of adults seeking treatment for alcohol problems, increases in alcohol consumption and alcohol\u2010related harm were observed following bariatric surgery. Despite improvement in risk factors for metabolic\u2010associated fatty liver disease after surgery, non\u2010invasive markers for hepatic fibrosis worsened, likely in the setting of harmful alcohol intake and associated liver injury. This supports the role of bariatric surgery pre\u2010operative assessment and post\u2010operative follow\u2010up to identify and manage alcohol\u2010related problems and associated liver disease risk.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/add.70487","type":"journal-article","created":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T09:59:33Z","timestamp":1780480773000},"page":"2682-2690","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Impact of bariatric surgery on alcohol\u2010use disorder and alcohol\u2010related liver disease: A retrospective study"],"prefix":"10.1111","volume":"121","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5506-8008","authenticated-orcid":false,"given":"Thomas J.","family":"Williams","sequence":"first","affiliation":[{"name":"Department of Gastroenterology and Hepatology Princess Alexandra Hospital  Brisbane Queensland Australia"},{"name":"Faculty of Health, Medicine and Behavioural Sciences The University of Queensland  Brisbane Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1795-6554","authenticated-orcid":false,"given":"Andrew J.","family":"Palmer","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology Princess Alexandra Hospital  Brisbane Queensland Australia"},{"name":"Faculty of Health, Medicine and Behavioural Sciences The University of Queensland  Brisbane Australia"},{"name":"Alcohol and Drug Assessment Unit Princess Alexandra Hospital  Brisbane Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7020-1196","authenticated-orcid":false,"given":"Jason P.","family":"Connor","sequence":"additional","affiliation":[{"name":"Faculty of Health, Medicine and Behavioural Sciences The University of Queensland  Brisbane Australia"},{"name":"Alcohol and Drug Assessment Unit Princess 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