{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T08:40:00Z","timestamp":1792485600731,"version":"4.5.0"},"reference-count":39,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T00:00:00Z","timestamp":1792454400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T00:00:00Z","timestamp":1792454400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Addiction"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>This study examined e\u2010cigarette flavor use and its prospective association with short\u2010term e\u2010cigarette abstinence among youth (12\u201317\u2009years old), young adults (18\u201324\u2009years old) and adults (25+\u2009years old) using United States (US)\u2010representative data.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Design<\/jats:title>\n                    <jats:p>Observational study using longitudinal data obtained from the Population Assessment of Tobacco and Health (PATH) study, waves 4\u20137 (2016\u20132023). A lagged design assessed three wave\u2010pairings per participant.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting<\/jats:title>\n                    <jats:p>Household computer\u2010assisted self\u2010interviews of US youth and adults from 2016 to 2023.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Participants<\/jats:title>\n                    <jats:p>\n                      A total of\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u20098418 non\u2010institutionalized youth and adults in the US.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Measurements<\/jats:title>\n                    <jats:p>The primary exposure was past 30\u2010day e\u2010cigarette flavor use at the previous wave using the following mutually exclusive flavor groupings: exclusive tobacco flavor or flavorless e\u2010cigarette use, exclusive menthol\/mint flavor, exclusive sweet flavors (e.g. candy, fruit, chocolate, clove\/spice) or use of multiple e\u2010cigarette flavors (defined as individuals vaping multiple flavor combinations from: tobacco\/flavorless, menthol\/mint and sweet flavors); the primary outcome was past 30\u2010day e\u2010cigarette abstinence at the subsequent wave (yes\/no). Generalized estimating equation (GEE) models examined prospective association between e\u2010cigarette flavor type and covariates [e.g. demographics, e\u2010cigarette dependence (time to first e\u2010cigarette: \u2264 30\u2009minutes of waking vs. &gt; 30\u2009minutes), dual cigarette and e\u2010cigarette use (yes\/no)], on e\u2010cigarette abstinence (primary outcome). We ran an overall GEE model adjusting for age group and three individual GEE models stratified by age group. All estimates were weighted.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Exclusive sweet flavors were the most common e\u2010cigarette flavor used among youth (46%), young adults (44%) and adults (41%). In the adjusted model, young adults [adjusted odds ratio (AOR) = 3.63, 95% confidence interval (CI) = 3.0\u20134.3,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u20090.001] and adults (AOR = 4.58, 95% CI = 3.8\u20135.6,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u20090.001) who vaped in the past 30\u2009days had higher odds of subsequent e\u2010cigarette abstinence compared with youth who vaped in the past 30\u2009days. Across ages, among past 30\u2010day vapers, exclusive tobacco\/flavorless e\u2010cigarette use was prospectively associated with increased e\u2010cigarette abstinence (AOR = 2.2, 95% CI = 1.9\u20132.5,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u20090.001), multiple\u2010flavor\u2010use was associated with decreased e\u2010cigarette abstinence (AOR = 0.61, 95% CI = 0.53\u20130.71,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u20090.001), compared with exclusive menthol or sweet\u2010flavored e\u2010cigarette use. Dual e\u2010cigarette and cigarette use was prospectively associated with reduced e\u2010cigarette abstinence in young adults (AOR = 0.60, 95% CI = 0.50\u20130.80,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u20090.001), yet increased e\u2010cigarette abstinence in adults (AOR = 1.4, 95% CI = 1.1\u20131.6,\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u20090.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Summary<\/jats:title>\n                    <jats:p>Among adults and youth in the United States, exclusive vaping of sweet, menthol or multiple flavors, compared with tobacco\/flavorless products, appears to decrease odds of later short\u2010term e\u2010cigarette abstinence.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/add.70674","type":"journal-article","created":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T08:06:08Z","timestamp":1792483568000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Flavored e\u2010cigarette use and its association with subsequent short\u2010term e\u2010cigarette abstinence among youth, young adults and adults: Findings from the United States longitudinal population assessment of tobacco use and health, 2016 to 2023"],"prefix":"10.1111","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7842-9080","authenticated-orcid":false,"given":"Joanna M.","family":"Streck","sequence":"first","affiliation":[{"name":"Center for Addiction Medicine, Department of Psychiatry Massachusetts General Hospital  Boston MA USA"},{"name":"Harvard Medical School  Boston MA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1135-6195","authenticated-orcid":false,"given":"Andrew S.","family":"Hyatt","sequence":"additional","affiliation":[{"name":"Harvard Medical School  Boston MA USA"},{"name":"Health Evaluation Research Lab, Department of Psychiatry Cambridge Health Alliance  Cambridge MA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5710-9301","authenticated-orcid":false,"given":"Randi M.","family":"Schuster","sequence":"additional","affiliation":[{"name":"Center for Addiction Medicine, Department of Psychiatry Massachusetts General Hospital  Boston MA USA"},{"name":"Harvard Medical School  Boston MA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jodi","family":"Gilman","sequence":"additional","affiliation":[{"name":"Center for Addiction Medicine, Department of Psychiatry Massachusetts General Hospital  Boston MA USA"},{"name":"Harvard Medical School  Boston MA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sharon","family":"Levy","sequence":"additional","affiliation":[{"name":"Harvard Medical School  Boston MA USA"},{"name":"Division of Addiction Medicine Boston Children's Hospital  Boston MA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathan P.","family":"Winickoff","sequence":"additional","affiliation":[{"name":"Harvard Medical School  Boston MA USA"},{"name":"Department of Pediatrics Massachusetts General Hospital  Boston MA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A. 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