{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,20]],"date-time":"2026-06-20T13:54:45Z","timestamp":1781963685128,"version":"3.54.5"},"reference-count":7,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2015,7,24]],"date-time":"2015-07-24T00:00:00Z","timestamp":1437696000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Australian Dental Journal"],"published-print":{"date-parts":[[2015,9]]},"abstract":"Abstract<\/jats:title>Oral squamous cell carcinoma (OSCC<\/jats:styled-content>) is one of the most common solid tumours occurring after haematopoietic stem cell transplantation (HSCT<\/jats:styled-content>), especially in patients with chronic graft\u2010versus\u2010host\u2010disease (cGVHD<\/jats:styled-content>). We describe a case of OSCC<\/jats:styled-content> that developed in a 51\u2010year\u2010old male 22\u00a0years after he had received allogeneic HSCT<\/jats:styled-content> from his human leukocyte antigen\u2010identical sister as a treatment for acute myelocytic leukaemia. The patient had presented with multiple white patchy lesions on the palatal gingiva and mucosa 16\u00a0years after HSCT<\/jats:styled-content>; these lesions were consistent with the clinical features of cGVHD<\/jats:styled-content>. Six years later, oral examination and biopsy revealed upper gingival squamous cell carcinoma (SCC<\/jats:styled-content>) in areas of cGVHD<\/jats:styled-content>, and he underwent tumour excision. Follow\u2010up examination at 2\u00a0years and 4\u00a0months after the operation revealed no evidence of recurrence of local SCC<\/jats:styled-content> or metastasis of the cervical lymph node. The current case highlights the susceptibility of patients with cGVHD<\/jats:styled-content> to the development of OSCC<\/jats:styled-content> even two decades after HSCT<\/jats:styled-content>. Therefore, we recommend careful long\u2010term follow\u2010up of the oral cavity for patients with cGVHD<\/jats:styled-content>.<\/jats:p>","DOI":"10.1111\/adj.12343","type":"journal-article","created":{"date-parts":[[2015,7,24]],"date-time":"2015-07-24T08:24:54Z","timestamp":1437726294000},"page":"404-407","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["A case of upper gingiva carcinoma with chronic graft\u2010versus\u2010host disease after allogenic bone marrow transplantation"],"prefix":"10.1111","volume":"60","author":[{"given":"F","family":"Tsushima","sequence":"first","affiliation":[{"name":"Oral and Maxillofacial Surgery Department of Oral Health Sciences Graduate School of Medical and Dental Sciences Tokyo Medical and Dental University Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J","family":"Sakurai","sequence":"additional","affiliation":[{"name":"Oral and Maxillofacial Surgery Department of Oral Health Sciences Graduate School of Medical and Dental Sciences Tokyo Medical and Dental University Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H","family":"Harada","sequence":"additional","affiliation":[{"name":"Oral and Maxillofacial Surgery Department of Oral Health Sciences Graduate School of Medical and Dental Sciences Tokyo Medical and Dental University Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,7,24]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V91.6.1833"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199703273361301"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/bmt.2011.23"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.oraloncology.2005.02.001"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbmt.2005.09.004"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2004-09-3411"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1038\/bmt.2011.77"}],"container-title":["Australian Dental Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fadj.12343","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/adj.12343","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,5]],"date-time":"2023-10-05T08:50:29Z","timestamp":1696495829000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/adj.12343"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,7,24]]},"references-count":7,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2015,9]]}},"alternative-id":["10.1111\/adj.12343"],"URL":"https:\/\/doi.org\/10.1111\/adj.12343","archive":["Portico"],"relation":{},"ISSN":["0045-0421","1834-7819"],"issn-type":[{"value":"0045-0421","type":"print"},{"value":"1834-7819","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,7,24]]},"assertion":[{"value":"2014-08-17","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2015-07-24","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}