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Following random allocation of either quadrants of the selected jaw to test or control treatment, conventional non\u2010surgical periodontal therapy (<jats:styled-content style=\"fixed-case\">NSPT<\/jats:styled-content>) was performed. In addition, the test side received adjunct photodynamic therapy. Probing depth (<jats:styled-content style=\"fixed-case\">PD<\/jats:styled-content>), clinical attachment level, bleeding on probing (BoP) and plaque scores (<jats:styled-content style=\"fixed-case\">PS<\/jats:styled-content>%) were recorded at phase 0 (baseline), phase 1 (immediately after <jats:styled-content style=\"fixed-case\">NSPT<\/jats:styled-content>), phase 2 (7\u00a0days following <jats:styled-content style=\"fixed-case\">NSPT<\/jats:styled-content>), phase 3 (1\u00a0month following <jats:styled-content style=\"fixed-case\">NSPT<\/jats:styled-content>) and phase 4 (3\u00a0months following <jats:styled-content style=\"fixed-case\">NSPT<\/jats:styled-content>). Subgingival plaque samples for quantification of Aa by real\u2010time polymerase chain reaction was performed at phases 0, 1, 2 and 4.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There was a significant clinical improvement at phases 3 and 4 compared with baseline while BoP reduced significantly only in the test group at phase 4. However, no difference in the quantification of Aa was detected between the groups.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Within the limits of the study, <jats:styled-content style=\"fixed-case\">PDT<\/jats:styled-content> adjunct to scaling and root planing does not lead to quantitative reduction of Aa in periodontitis patients.<\/jats:p><\/jats:sec>","DOI":"10.1111\/adj.12409","type":"journal-article","created":{"date-parts":[[2016,1,18]],"date-time":"2016-01-18T14:40:49Z","timestamp":1453128049000},"page":"440-445","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":31,"title":["Effect of photodynamic therapy adjunct to scaling and root planing in periodontitis patients: A randomized clinical 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