{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,27]],"date-time":"2026-07-27T17:41:17Z","timestamp":1785174077632,"version":"3.55.0"},"reference-count":12,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2016,12,23]],"date-time":"2016-12-23T00:00:00Z","timestamp":1482451200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Australian Dental Journal"],"published-print":{"date-parts":[[2017,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Granulomatosis with polyangiitis (<jats:styled-content style=\"fixed-case\">GPA<\/jats:styled-content>) is a potentially lethal disease characterized by systemic necrotizing vasculitis, which affects small\u2010 and medium\u2010sized blood vessels and is often associated with serum cytoplasmic antineutrophil cytoplasmic antibody. The upper and lower respiratory tract and kidney are the most involved sites, but oral lesions can be identified in 6\u201313% of the cases, whereas in only 2% of the cases, oral manifestations represent the first signal of the disease usually as gingival swellings or unspecific ulcerations. Without treatment, the mainstay of which is the combination of immunosuppressants and systemic corticosteroids, <jats:styled-content style=\"fixed-case\">GPA<\/jats:styled-content> may run a fatal course. In this report we describe an original case of <jats:styled-content style=\"fixed-case\">GPA<\/jats:styled-content> affecting a 75\u2010year\u2010old female patient referred to our service due to a gingival swelling with 3\u2010month duration. Although the patient was correctly diagnosed and promptly treated, she died 3\u00a0months after the initial diagnosis.<\/jats:p>","DOI":"10.1111\/adj.12441","type":"journal-article","created":{"date-parts":[[2016,7,21]],"date-time":"2016-07-21T07:42:48Z","timestamp":1469086968000},"page":"102-106","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Gingival granulomatosis with polyangiitis (Wegener's granulomatosis) as a primary manifestation of the disease"],"prefix":"10.1111","volume":"62","author":[{"given":"FP","family":"Fonseca","sequence":"first","affiliation":[{"name":"Department of Oral Diagnosis Piracicaba Dental School University of Campinas Piracicaba Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"BM","family":"Benites","sequence":"additional","affiliation":[{"name":"Oral Medicine Department S\u00edrio\u2010Liban\u00eas Hospital S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"ALV","family":"Ferrari","sequence":"additional","affiliation":[{"name":"Department of Rheumatology School of Medical Sciences University of Campinas Campinas Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Z","family":"Sachetto","sequence":"additional","affiliation":[{"name":"Department of Rheumatology School of Medical Sciences University of Campinas Campinas Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"GV","family":"de Campos","sequence":"additional","affiliation":[{"name":"Periodontist at Private Practice S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"OP","family":"de Almeida","sequence":"additional","affiliation":[{"name":"Department of Oral Diagnosis Piracicaba Dental School University of Campinas Piracicaba Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"ER","family":"Fregnani","sequence":"additional","affiliation":[{"name":"Oral Medicine Department S\u00edrio\u2010Liban\u00eas Hospital S\u00e3o Paulo Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,12,23]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaut.2014.01.028"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tripleo.2005.04.018"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.autrev.2014.08.017"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/jop.12030"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejim.2009.09.013"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0714.2012.01141.x"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.4317\/medoral.15.e601"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejim.2009.04.007"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.24328"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1067\/S0190-9622(03)00556-5"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.lpm.2015.04.008"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncprheum0269"}],"container-title":["Australian Dental Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fadj.12441","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fadj.12441","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/adj.12441","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,23]],"date-time":"2023-09-23T13:32:08Z","timestamp":1695475928000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/adj.12441"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,12,23]]},"references-count":12,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2017,3]]}},"alternative-id":["10.1111\/adj.12441"],"URL":"https:\/\/doi.org\/10.1111\/adj.12441","archive":["Portico"],"relation":{},"ISSN":["0045-0421","1834-7819"],"issn-type":[{"value":"0045-0421","type":"print"},{"value":"1834-7819","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,12,23]]},"assertion":[{"value":"2016-07-17","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2016-12-23","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}