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Both present similarly with loss of supporting soft and hard tissue around dental implants; therefore, a careful differential diagnosis is required. The present case concerns a 62\u2010year\u2010old Japanese man who had a dental implant which had been in the left maxillary incisor region for 4 years who apparently developed peri\u2010implantitis. This did not respond to localized therapy and antibiotics so was referred for specialist surgical management. A biopsy confirmed it to be a squamous cell carcinoma rather than an inflammatory lesion. A literature review shows that this is an unusual presentation without a previous history of malignancy, mucosal disease or risk factors for cancers. Although rare, the possibility of peri\u2010implant squamous cell carcinoma should be borne in mind by all practitioners who monitor implant patients.<\/jats:p>","DOI":"10.1111\/adj.12581","type":"journal-article","created":{"date-parts":[[2017,12,27]],"date-time":"2017-12-27T18:54:08Z","timestamp":1514400848000},"page":"261-264","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Peri\u2010implant squamous cell carcinoma"],"prefix":"10.1111","volume":"63","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3879-1963","authenticated-orcid":false,"given":"K","family":"Ito","sequence":"first","affiliation":[{"name":"Oral and Maxillofacial Surgery Unit Faculty of Health Science University of Adelaide Adelaide South Australia Australia"},{"name":"Department of Maxillofacial Surgery Nihon University School of Dentistry at Matsudo Matsudo 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