{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T14:46:40Z","timestamp":1740149200918,"version":"3.37.3"},"reference-count":38,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2018,10,15]],"date-time":"2018-10-15T00:00:00Z","timestamp":1539561600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Australian Dental Journal"],"published-print":{"date-parts":[[2019,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The aim of the study was to evaluate the use of enamel matrix derivative (<jats:styled-content style=\"fixed-case\">EMD<\/jats:styled-content>) alone or in association with deproteinized bovine bone mineral (<jats:styled-content style=\"fixed-case\">DBBM<\/jats:styled-content>) for the treatment of partially contained intrabony defects.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A total of 20 two\u2010walled intrabony defects belonging to nine patients were included. Ten defects were treated with <jats:styled-content style=\"fixed-case\">EMD<\/jats:styled-content> alone (test group 1) and the other 10 were treated with <jats:styled-content style=\"fixed-case\">EMD<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">DBBM<\/jats:styled-content> (test group 2), applying either modified papilla preservation technique or simplified papilla preservation technique.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Twelve months after surgery, in the test group 1, <jats:styled-content style=\"fixed-case\">PD<\/jats:styled-content> was 2.8 \u00b1 0.8 mm, <jats:styled-content style=\"fixed-case\">REC<\/jats:styled-content> was 2.3 \u00b1 2.4 mm and <jats:styled-content style=\"fixed-case\">CAL<\/jats:styled-content> was 5.0 \u00b1 2.8 mm, significantly reduced from baseline values (<jats:italic>P<\/jats:italic> &lt; 0.05). Likewise, in test group 2, <jats:styled-content style=\"fixed-case\">PD<\/jats:styled-content>,<jats:styled-content style=\"fixed-case\"> REC<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">CAL<\/jats:styled-content> reduced to 3.0 \u00b1 0.7 mm, 3.9 \u00b1 1.5 mm and 6.9 \u00b1 1.1 mm respectively, from baseline values at 12 months (<jats:italic>P<\/jats:italic> &lt; 0.05). No significant differences between groups were found.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The results showed that the use of <jats:styled-content style=\"fixed-case\">EMD<\/jats:styled-content> alone and the use of a combination of <jats:styled-content style=\"fixed-case\">EMD<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">DBBM<\/jats:styled-content> for the treatment of partially contained defects showed comparable clinical and radiographic outcomes after 12 months.<\/jats:p><\/jats:sec>","DOI":"10.1111\/adj.12654","type":"journal-article","created":{"date-parts":[[2018,9,26]],"date-time":"2018-09-26T19:48:50Z","timestamp":1537991330000},"page":"27-34","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Enamel matrix derivative for the treatment of partially contained intrabony defects: 12\u2010month results"],"prefix":"10.1111","volume":"64","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8428-8811","authenticated-orcid":false,"given":"S","family":"Corbella","sequence":"first","affiliation":[{"name":"Department of Biomedical, Surgical and Dental Sciences Universit\u00e0 degli Studi di Milano Milan Italy"},{"name":"IRCCS Istituto Ortopedico Galeazzi Milan Italy"},{"name":"Institute of Dentistry I. 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Sechenov First Moscow state medical University Moscow Russia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5017-1340","authenticated-orcid":false,"given":"A","family":"Alberti","sequence":"additional","affiliation":[{"name":"Department of Biomedical, Surgical and Dental Sciences Universit\u00e0 degli Studi di Milano Milan Italy"},{"name":"IRCCS Istituto Ortopedico Galeazzi Milan Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8781-1997","authenticated-orcid":false,"given":"E","family":"Calciolari","sequence":"additional","affiliation":[{"name":"Centre for Oral Clinical Research &amp; Centre for Oral Immunobiology and Regenerative Medicine Institute of Dentistry, Barts and The London School of Medicine and Dentistry Queen Mary University of London London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7866-5024","authenticated-orcid":false,"given":"S","family":"Taschieri","sequence":"additional","affiliation":[{"name":"Department of Biomedical, Surgical and Dental Sciences Universit\u00e0 degli Studi di Milano Milan Italy"},{"name":"IRCCS Istituto Ortopedico Galeazzi Milan Italy"},{"name":"Institute of Dentistry I. 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