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Occasionally, the clinical features of these more common benign lesions, or others nonrelated to implants, might be similar to oral malignancies, leading to misdiagnosis. The objective of this study was to present a case series of oral cancer located adjacent to dental implants, aimed to identify the reasons for initial misinterpretation of diagnosis. Thirteen patients, 10 females and 3 males, aged 59 to 90, were assessed. Among the differential diagnoses established, a malignant or premalignant lesion was not considered in 10 out of the 13 patients. Peri\u2010implantitis was the most common preliminary diagnosis, followed by fungal infection, viral infections, and traumatic ulcers. The meantime for the diagnosis of oral cancer was 21.5\u00a0months. The clinical presentation of peri\u2010implant malignancy, such as ulceration, white and red plaques, and exophytic lesions, might mimic benign diseases that are more common in the oral cavity. Suspicious lesions with treatment failure that persist for more than 2\u00a0weeks require biopsy and histopathological analysis to establish an early definitive diagnosis to improve the prognosis and quality of life of the patients.<\/jats:p>","DOI":"10.1111\/adj.12793","type":"journal-article","created":{"date-parts":[[2020,9,17]],"date-time":"2020-09-17T05:37:20Z","timestamp":1600321040000},"page":"112-118","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Oral cancer adjacent to dental implants mimicking benign lesions: a case series study"],"prefix":"10.1111","volume":"66","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4798-584X","authenticated-orcid":false,"given":"Marisol","family":"Miranda Galvis","sequence":"first","affiliation":[{"name":"Department of Oral Diagnosis Piracicaba Dental School University of Campinas Piracicaba Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7542-476X","authenticated-orcid":false,"given":"Isabel","family":"Schausltz Pereira Faustino","sequence":"additional","affiliation":[{"name":"Department of Oral Diagnosis Piracicaba Dental School University of Campinas Piracicaba Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7640-0719","authenticated-orcid":false,"given":"Joab","family":"Cabral Ramos","sequence":"additional","affiliation":[{"name":"Department of Oral Diagnosis Piracicaba Dental School University of Campinas Piracicaba Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2040-6617","authenticated-orcid":false,"given":"Alan Roger","family":"dos Santos Silva","sequence":"additional","affiliation":[{"name":"Department of Oral Diagnosis Piracicaba Dental School University of Campinas Piracicaba Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3372-1536","authenticated-orcid":false,"given":"F\u00e1bio","family":"de Abreu Alves","sequence":"additional","affiliation":[{"name":"Department of Stomatology A.C. 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