{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T23:35:15Z","timestamp":1792452915454,"version":"4.5.0"},"reference-count":30,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2021,3,13]],"date-time":"2021-03-13T00:00:00Z","timestamp":1615593600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100004263","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado do Rio Grande do Sul","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004263","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Australian Dental Journal"],"published-print":{"date-parts":[[2021,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Syphilis is an infectious, sexually transmitted disease with varied oral manifestations, that can mimic other lesions. This study aimed to conduct an epidemiological survey of cases of syphilis, diagnosed from oral manifestations, establishing the sociodemographic profile of patients and clinical characteristics of oral lesions.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The medical records of patients with oral lesions of syphilis acquired were reviewed, and 109 cases were selected.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The mean age of the patients was 34.4\u00a0years and, of these, 51% were male. In 105 cases, the disease was diagnosed in the secondary stage; in three cases, in the primary stage; and, in one case, in the tertiary stage. The cases of primary syphilis presented as single and ulcerated nodules, and the case of tertiary syphilis, as a necrotic lesion in the palate. In 86% of cases of secondary syphilis, there were multicentric lesions, presenting as grayish\u2010white plaques (85%), associated or not with erosive and\/or ulcerated lesions (33%), mostly affecting the labial mucosa and tongue. In 91.7% of cases painful symptoms were reported.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Considering the increase in syphilis, it is extremely important that dentists recognize its oral manifestations, because early diagnosis and treatment can minimize the risks of complications and transmission.<\/jats:p><\/jats:sec>","DOI":"10.1111\/adj.12834","type":"journal-article","created":{"date-parts":[[2021,3,3]],"date-time":"2021-03-03T16:56:04Z","timestamp":1614790564000},"page":"289-294","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["Oral manifestations of syphilis: an epidemiological study in southern Brazil"],"prefix":"10.1111","volume":"66","author":[{"given":"MA","family":"Thums","sequence":"first","affiliation":[{"name":"Oral Medicine Division Pontifical Catholic University of Rio Grande do Sul\u2010PUCRS Porto Alegre Rio Grande do Sul Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5119-7347","authenticated-orcid":false,"given":"VS","family":"Koth","sequence":"additional","affiliation":[{"name":"Oral Medicine Division Pontifical Catholic University of Rio Grande do Sul\u2010PUCRS Porto Alegre Rio Grande do Sul Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"MAZ","family":"de Figueiredo","sequence":"additional","affiliation":[{"name":"Oral Medicine Division Pontifical Catholic University of Rio Grande do Sul\u2010PUCRS Porto Alegre Rio Grande do Sul Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K","family":"Cherubini","sequence":"additional","affiliation":[{"name":"Oral Medicine Division Pontifical Catholic University of Rio Grande do Sul\u2010PUCRS Porto Alegre Rio Grande do Sul Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"FG","family":"Salum","sequence":"additional","affiliation":[{"name":"Oral Medicine Division Pontifical Catholic University of Rio Grande do Sul\u2010PUCRS Porto Alegre Rio Grande do Sul Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,3,13]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1590\/S1807-59322006000200012"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cnur.2020.06.009"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrdp.2017.73"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12105-016-0703-z"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.spid.2005.06.005"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1086\/429626"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12105-009-0127-0"},{"key":"e_1_2_8_9_1","first-page":"e138","article-title":"Oral findings in secondary syphilis","volume":"23","author":"De Andrade RS","year":"2018","journal-title":"Med Oral Patol Oral y Cir Bucal"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/00007435-199704000-00002"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2230.2006.02163.x"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra1901593"},{"key":"e_1_2_8_13_1","first-page":"71","article-title":"The great imitator revealed: syphilis","volume":"27","author":"Klausner JD","year":"2019","journal-title":"Top Antivir Med"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/odi.12058"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.2471\/BLT.18.228486"},{"key":"e_1_2_8_16_1","first-page":"1","article-title":"Trends of syphilis in Brazil: a growth portrait of the treponemic epidemic","volume":"15","author":"Dos Santos MM","year":"2020","journal-title":"PLoS One"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2020.04.089"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjorl.2018.12.010"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijom.2018.10.023"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1177\/2324709618820355"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijid.2015.04.007"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.oooo.2015.09.022"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.oooo.2012.04.028"},{"key":"e_1_2_8_24_1","unstructured":"PetruccelliJL SaboiaAL.Caracter\u00edsticas \u00e9tnico\u2010raciais da popula\u00e7\u00e3o. Classifica\u00e7\u00f5es e identidades. Estudos e an\u00e1lises. Informa\u00e7\u00e3o demogr\u00e1fica e socioecon\u00f4mica. Instituto Brasileiro de Geografia e Estat\u00edstica\u2014IBGE: Rio de Janeiro2013."},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1093\/jalm\/jfaa163"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.26633\/RPSP.2019.17"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12939-017-0589-8"},{"key":"e_1_2_8_28_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1445-5994.2012.02814.x"},{"key":"e_1_2_8_29_1","doi-asserted-by":"publisher","DOI":"10.1071\/SH11102"},{"key":"e_1_2_8_30_1","unstructured":"BRASIL_Ministerio da Saude_ Secretaria de Vigil\u00e2ncia em Sa\u00fade.Boletim Epidemiol\u00f3gico.2020. URL:http:\/\/www.aids.gov.br\/pt\u2010br\/pub\/2020\/boletim\u2010sifilis\u20102020. Accessed 10 February 2021."},{"key":"e_1_2_8_31_1","first-page":"2011","article-title":"Underreporting of gestational, congenital and acquired syphilis among indigenous peoples in Mato Grosso do Sul State, Brazil, 2011\u20132014","volume":"26","author":"Graeff SV","year":"2014","journal-title":"Epidemiologia e Servi\u00e7os de Sa\u00fade"}],"container-title":["Australian Dental Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/adj.12834","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/adj.12834","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/adj.12834","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,29]],"date-time":"2023-08-29T20:10:19Z","timestamp":1693339819000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/adj.12834"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,3,13]]},"references-count":30,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2021,9]]}},"alternative-id":["10.1111\/adj.12834"],"URL":"https:\/\/doi.org\/10.1111\/adj.12834","archive":["Portico"],"relation":{},"ISSN":["0045-0421","1834-7819"],"issn-type":[{"value":"0045-0421","type":"print"},{"value":"1834-7819","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,3,13]]},"assertion":[{"value":"2021-02-26","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-03-13","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}